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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Key result
Water solubility:
308 mg/L
Temp.:
20 °C
pH:
>= 7.58 - <= 7.66
Details on results:
Preliminary test
Through the serial volume addition of water to the test item, it was shown that the water solubility of the test item was estimated between 500 and 1000 mg/L at 20 °C.

The following concentrations were obtained in the solutions prepared for the hydrosolubility determination.

 

 

Reference of

Test solutions

Peak area

(area units)

Peak area (area units) mean

Conc.

(mg/L)

Dilution

factor

Final conc.

(mg/L)

A

C= (A-b)/a (cal)

Df

Cf= C x Df

After 24h

12-218 A6-A dil50

12-218 A6-A dil50

7.5083

7.4756

7.4920

6.10

50

305

12-218 A6-B dil50

12-218 A6-B dil50

7.6138

7.5796

7.5967

6.18

50

309

After 48h

12-218 A6-C dil50

12-218 A6-C dil50

7.5232

7.5625

7.5429

6.14

50

307

12-218 A6-D dil50

12-218 A6-D dil50

7.5100

7.5128

7.5114

6.11

50

306

After 72h

12-218 A6-E dil50

12-218 A6-E dil50

7.6717

7.6491

7.6604

6.24

50

312

12-218 A6-F dil50

12-218 A6-F dil50

7.6534

7.6547

7.6541

6.23

50

312

 

The measured pH of the aqueous phases were between 7.58 and 7.66 at 20°C +/- 1 °C.

 

mean

308

SD

2.99

RSD

0.97%

 

The mean concentration in silicate is equal to 308 mg/L with an RSD of 0.97%. As the RSD is lower than 15%, the result is acceptable.

 

Conclusions:
Interpretation of results (migrated information): moderately soluble (100-1000 mg/L)
the solubility in water of tetramethylthiuram monosulphide is equal to 308 mg/L at 20°C ± 1 °C.
Executive summary:

The solubility in water of tetramethylthiuram monosulphide was determined in a GLP study according to the OECD 105 guideline. Using the shake-flask method, its solubility is equal to 308 mg/L at 20°C ± 1 °C.

Description of key information

Key value for chemical safety assessment

Water solubility:
308 mg/L
at the temperature of:
20 °C

Additional information

The solubility in water of tetramethylthiuram monosulphide was determined in a GLP study according to the OECD 105 guideline. Using the shake-flask method, its solubility is equal to 308 mg/L at 20°C ± 1 °C.