Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
supporting study

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Unnamed
Year:
2009
Report date:
2009
Reference Type:
secondary source
Title:
Unnamed
Year:
2001

Materials and methods

Principles of method if other than guideline:
Method data are not available as the report details are unpublished.
GLP compliance:
yes
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Warfarin
EC Number:
201-377-6
EC Name:
Warfarin
Cas Number:
81-81-2
Molecular formula:
C19H16O4
IUPAC Name:
4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one

Results and discussion

Partition coefficientopen allclose all
Type:
log Pow
Partition coefficient:
2.9
pH:
4
Remarks on result:
other: 30-35 °C
Type:
log Pow
Partition coefficient:
0.7
pH:
7
Remarks on result:
other: 30-35 °C
Type:
log Pow
Partition coefficient:
0.6
pH:
9
Remarks on result:
other: 30-35 °C

Applicant's summary and conclusion