Information from the Existing Substances Regulation (ESR)
Information from the Existing Substances Regulation (ESR)
Before REACH entered into force, chemicals were regulated by a number of different regulations and directives. The Council Regulation (EEC) No 793/93 -- also known as the Existing Substances Regulation (ESR) -- was one of these. It introduced a comprehensive framework for the evaluation and control of "existing substances" (substances on the market before 1982).
The ESR stated that the Commission, in consultation with the Member States, would regularly draw up lists of priority substances which require immediate attention because of their potential effects to human health or the environment. Between 1994 and 2007 (the entry into force of REACH), four such priority lists were published, with a total of 141 substances.
Ethylbenzene | 202-849-4 | 100-41-4 | 1 |
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Styrene | 202-851-5 | 100-42-5 | 1 |
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Methenamine | 202-905-8 | 100-97-0 | 2 |
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Bis(hydroxylammonium) | 233-118-8 | 10039-54-0 | 3 |
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Boric acid, crude natural | 233-139-2 | 10043-35-3 | 4 |
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4,4'- Diaminodiphenylmethane (MDA) | 202-974-4 | 101-77-9 | 1 |
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Cobalt(II) dinitrate | 233-402-1 | 10141-05-6 | ||||||
2-ethylhexyl acrylate | 203-080-7 | 103-11-7 | 1 |
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1,4-Dichlorobenzene (p-dichlorobenzene) | 203-400-5 | 106-46-7 | 1 |
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Buta-1,3-diene | 203-450-8 | 106-99-0 | 1 |
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Acrolein | 203-453-4 | 107-02-8 | 1 |
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Acrylonitrile | 203-466-5 | 107-13-1 | 1 |
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Dimethyldioctadecylammonium chloride | 203-508-2 | 107-64-2 | 1 |
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1-methoxypropan-2-ol (PGME) | 203-539-1 | 107-98-2 | 4 |
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Vinyl acetate | 203-545-4 | 108-05-4 | 1 |
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2-methoxy-1-methylethyl acetate (PGMA) | 203-603-9 | 108-65-6 | 4 |
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Toluene | 203-625-9 | 108-88-3 | 2 |
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Phenol | 203-632-7 | 108-95-2 | 1 |
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Pentane | 203-692-4 | 109-66-0 | 2 |
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2-methoxyethyl acetate | 203-772-9 | 110-49-6 | 1 | |||||
But-2-yne-1,4-diol | 203-788-6 | 110-65-6 | 1 |
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2-Ethoxyethanol | 203-804-1 | 110-80-5 | 2 |
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Cyclohexane | 203-806-2 | 110-82-7 | 1 |
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Piperazine | 203-808-3 | 110-85-0 | 3 |
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2-Ethoxyethyl acetate | 203-839-2 | 111-15-9 | 2 |
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2-butoxyethanol | 203-905-0 | 111-76-2 | 4 |
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2-(2-methoxyethoxy)ethanol (DEGME) | 203-906-6 | 111-77-3 | 1 |
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Boric acid | 234-343-4 | 11113-50-1 | 4 |
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Perboric acid, sodium salt | 234-390-0 | 11138-47-9 | 3 |
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2-butoxyethyl acetate | 203-933-3 | 112-07-2 | 4 |
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2-(2-butoxyethoxy)ethanol | 203-961-6 | 112-34-5 | 1 |
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(Z)-octadec-9-enylamine | 204-015-5 | 112-90-3 | 4 |
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Tris(2-chloroethyl)phosphate (TCEP) | 204-118-5 | 115-96-8 | 2 |
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Bis(pentabromophenyl) ether (decabromodiphenyl ether) (DecaBDE) | 214-604-9 | 1163-19-5 | 1 |
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Bis(2-ethylhexyl) phthalate (DEHP) | 204-211-0 | 117-81-7 | 2 |
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Dioctyl phthalate | 204-214-7 | 117-84-0 | 1 | |||||
Anthracene | 204-371-1 | 120-12-7 | 3 |
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1,2,4 Trichlorobenzene | 204-428-0 | 120-82-1 | 2 |
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2,4-Dinitrotoluene | 204-450-0 | 121-14-2 | 4 |
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Diphenylamine | 204-539-4 | 122-39-4 | 3 |
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1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylin-deno[5,6-c]pyran | 214-946-9 | 1222-05-5 | 4 |
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1,4-dioxane | 204-661-8 | 123-91-1 | 2 |
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Octadecylamine | 204-695-3 | 124-30-1 | 4 |
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Tetrachloroethylene | 204-825-9 | 127-18-4 | 1 |
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Cadmium oxide | 215-146-2 | 1306-19-0 | 3 |
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Diantimony trioxide | 215-175-0 | 1309-64-4 | 4 |
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Sodium hydroxide | 215-185-5 | 1310-73-2 | 4 |
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Nickel dinitrate | 236-068-5 | 13138-45-9 | 4 |
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Zinc oxide | 215-222-5 | 1314-13-2 | 2 |
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Disodium tetraborate, anhydrous | 215-540-4 | 1330-43-4 | 4 |
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Chromium trioxide | 215-607-8 | 1333-82-0 | 3 |
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tris(2-chloro-1-methylethyl) phosphate (TCPP) | 237-158-7 | 13674-84-5 | 4 |
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Tris[2-chloro-1-(chloromethyl)ethyl] phosphate (TDCP) | 237-159-2 | 13674-87-8 | 4 |
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Cryolite (Trisodium hexafluoroaluminate) | 237-410-6 | 13775-53-6 | 3 |
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Ethyl acetoacetate | 205-516-1 | 141-97-9 | 1 |
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1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naph-thyl)ethan-1-one | 216-133-4 | 1506-02-1 | 4 |
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Cryolite (Trisodium hexafluoroaluminate) | 239-148-8 | 15096-52-3 | 3 |
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4-chloro-o-cresol | 216-381-3 | 1570-64-5 | 1 |
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Tert-butyl methyl ether | 216-653-1 | 1634-04-4 | 3 |
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Nonylphenol | 246-672-0 | 25154-52-3 | 2 |
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Reaction mass of 2,4,4-Trimethylpent-1-ene and 2,4,4-Trimethylpent-2-ene | 246-690-9 | 25167-70-8 | 2 |
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Hexabromocyclododecane (HBCDD) | 247-148-4 | 25637-99-4 | 2 |
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Methylenediphenyl diisocyanate | 247-714-0 | 26447-40-5 | 3 |
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Tris(nonylphenyl) phosphite (TNPP) | 247-759-6 | 26523-78-4 | 4 |
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Di-isodecyl phthalate | 247-977-1 | 26761-40-0 | 2 |
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Di-isononyl phthalate | 249-079-5 | 28553-12-0 | 2 |
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2,3-epoxypropyltrimethylammonium chloride | 221-221-0 | 3033-77-0 | 3 |
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Pentanol | 250-378-8 | 30899-19-5 | 3 | |||||
Diphenyl ether, pentabromo derivative | 251-084-2 | 32534-81-9 | 2 |
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Diphenyl ether, octabromo derivative | 251-087-9 | 32536-52-0 | 1 |
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(3-chloro-2-hydroxypropyl) | 222-048-3 | 3327-22-8 | 3 |
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Nickel carbonate | 222-068-2 | 3333-67-3 | 4 |
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V6 (2,2-bis(chloromethyl) trimethylene bis[bis(2-chloroethyl)phosphate]) | 253-760-2 | 38051-10-4 | 4 |
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Trisodium nitrilotriacetate | 225-768-6 | 5064-31-3 | 3 |
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Zinc distearate, Fatty acids, C16-18, zinc salts |
209-151-9 293-049-4 |
557-05-1 91051-01-3 |
2 |
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Edetic acid | 200-449-4 | 60-00-4 | 1 |
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Amines, hydrogenated tallow alkyl | 262-976-6 | 61788-45-2 | 4 |
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Amines, coco alkyl | 262-977-1 | 61788-46-3 | 4 |
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Amines, tallow alkyl | 263-125-1 | 61790-33-8 | 2 |
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Aniline | 200-539-3 | 62-53-3 | 1 |
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Tetrasodium ethylenediaminetetraacetate | 200-573-9 | 64-02-8 | 1 |
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Distillates (coal tar) | 266-027-7 | 65996-92-1 | 1 | |||||
Pitch, coal tar, high temp. | 266-028-2 | 65996-93-2 | 3 |
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Chloroform | 200-663-8 | 67-66-3 | 2 |
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Benzene, C10-13-alkyl derivs | 267-051-0 | 67774-74-7 | 1 |
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1,2-Benzenedicarboxylic acid, di-C8-10-branched alkyl esters, C9-rich | 271-090-9 | 68515-48-0 | 2 |
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1,2-Benzenedicarboxylic acid, di-C9-11-branched alkyl esters, C10-rich | 271-091-4 | 68515-49-1 | 2 |
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Propan-1-ol | 200-746-9 | 71-23-8 | 2 |
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Benzene | 200-753-7 | 71-43-2 | 1 |
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Nickel | 231-111-4 | 7440-02-0 | 3 |
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Cadmium | 231-152-8 | 7440-43-9 | 3 |
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Zinc | 231-175-3 | 7440-66-6 | 2 |
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Acetonitrile | 200-835-2 | 75-05-8 | 1 |
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Chlorodifluoromethane | 200-871-9 | 75-45-6 | 2 |
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Methyloxirane (Propylene oxide) | 200-879-2 | 75-56-9 | 2 |
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TBHP (Hydroperoxide, 1,1-Dimethylethyl) | 200-915-7 | 75-91-2 | 3 |
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Zinc chloride | 231-592-0 | 7646-85-7 | 2 |
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Hydrogen fluoride | 231-634-8 | 7664-39-3 | 1 |
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Sodium hypochlorite | 231-668-3 | 7681-52-9 | 2 |
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Hexachlorocyclopentadiene | 201-029-3 | 77-47-4 | 4 |
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Dimethyl sulphate | 201-058-1 | 77-78-1 | 2 |
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Nickel dichloride | 231-743-0 | 7718-54-9 | 4 |
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Hydrogen peroxide | 231-765-0 | 7722-84-1 | 2 |
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Zinc sulphate | 231-793-3 | 7733-02-0 | 2 |
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Sodium chromate | 231-889-5 | 7775-11-3 | 3 |
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Potassium dichromate | 231-906-6 | 7778-50-9 | 3 |
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Trizinc bis(orthophosphate) | 231-944-3 | 7779-90-0 | 2 |
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Chlorine | 231-959-5 | 7782-50-5 | 3 |
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Aluminium fluoride | 232-051-1 | 7784-18-1 | 4 |
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Nickel sulphate | 232-104-9 | 7786-81-4 | 3 |
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Ammonium dichromate | 232-143-1 | 7789-09-5 | 3 |
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Sodium dichromate | 234-190-3 |
7789-12-0 10588-01-9 |
3 |
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Calcium fluoride | 232-188-7 | 7789-75-5 | 4 |
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Trichloroethylene | 201-167-4 | 79-01-6 | 1 |
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Acrylamide | 201-173-7 | 79-06-1 | 1 |
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Acrylic acid | 201-177-9 | 79-10-7 | 1 |
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Chloroacetic acid | 201-178-4 | 79-11-8 | 3 |
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Methyl acetate | 201-185-2 | 79-20-9 | 1 |
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Methacrylic acid | 201-204-4 | 79-41-4 | 1 |
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2,2,6,6-tetrabromo-4,4-isopropylidenediphenol | 201-236-9 | 79-94-7 | 4 |
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Bisphenol A,4,4'-isopropylidenediphenol | 201-245-8 | 80-05-7 | 3 |
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Methyl methacrylate | 201-297-1 | 80-62-6 | 1 |
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4-tert-butyl-2,6-dimethyl-3,5-dinitroacetophenone | 201-328-9 | 81-14-1 | 3 |
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5-tert-butyl-2,4,6-trinitro-m-xylene (Musk xylene) | 201-329-4 | 81-15-2 | 3 |
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Dibutyl phthalate | 201-557-4 | 84-74-2 | 1 |
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Phenol, 4-nonyl-, branched | 284-325-5 | 84852-15-3 | 2 |
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Benzyl butyl phthalate (BBP) | 201-622-7 | 85-68-7 | 3 |
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Alkanes, C10-13, chloro (Short Chain Chlorinated Paraffins) | 287-476-5 | 85535-84-8 | 1 |
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Alkanes, C14-17, chloro (MCCP, Medium chained chlorinated paraffins) | 287-477-0 | 85535-85-9 | 3 |
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1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | 2 |
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2-nitrotoluene | 201-853-3 | 88-72-2 | 4 |
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2-Methoxyaniline,o-Anisidine | 201-963-1 | 90-04-0 | 2 |
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Naphthalene | 202-049-5 | 91-20-3 | 1 |
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N-cyclohexylbenzothiazole- 2-sulphenamide | 202-411-2 | 95-33-0 | 2 |
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3,4-dichloroaniline | 202-448-4 | 95-76-1 | 1 |
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4-methyl-m-phenylenediamine (toluene-2,4-diamine) | 202-453-1 | 95-80-7 | 1 |
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2-furaldehyde | 202-627-7 | 98-01-1 | 2 |
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p-tert-butylphenol | 202-679-0 | 98-54-4 | 4 |
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4-tert-butylbenzoic acid | 202-696-3 | 98-73-7 | 4 |
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Cumene | 202-704-5 | 98-82-8 | 1 |
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Nitrobenzene | 202-716-0 | 98-95-3 | 3 |
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2-methoxy-2-methylbutane | 213-611-4 | 994-05-8 | 4 |
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