Summary of Classification and Labelling
Harmonised classification - Annex VI of Regulation (EC) No 1272/2008 (CLP Regulation)
General Information
Index Number EC / List no. CAS Number International Chemical Identification
603-076-00-9 203-788-6 110-65-6 but-2-yne-1,4-diol
2-butyne-1,4-diol

ATP Inserted / Updated: CLP00
CLP Classification (Table 3)
Classification Labelling Specific Concentration limits, M-Factors, Acute Toxicity Estimates (ATE) Notes
Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
Acute Tox. 3 * H301 H301 GHS08
GHS05
GHS06
Dgr
Eye Irrit. 2; H319: 25 % ≤ C < 50 %
Skin Corr. 1B; H314: C ≥ 50 %
Skin Irrit. 2; H315: 25 % ≤ C < 50 %
Note D
Acute Tox. 4 * H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 * H331 H331
STOT RE 2 * H373 ** H373 **

Signal Words Pictograms
Danger
GHS08
Health hazard
GHS05
Corrosion
GHS06
Skull and crossbones
Seveso III Data
Disclaimer: Please note that some of the substances covered by the Seveso Directive can belong to more than one Seveso categories. It will be up to the users to decide whether their substance or mixture fall in one or in more of these classification categories depending on the tonnage bands and the concentrations.
Please also note that ECHA is not an authority for the Seveso Directive and that the Seveso categorisation below is provided for information only. The Seveso III Directive (Directive 2012/18/EU repealing Directive 96/82/EC (Seveso II) from 1 June 2015) is the only authentic legal reference and that the information in this inventory does not constitute legal advice. For further information on Seveso, please ask your national authority.

Seveso Data
Seveso Substance Seveso Categories
Yes H2
Notified classification and labelling
General Information
EC / List no.
Name CAS Number
203-788-6 But-2-yne-1,4-diol 110-65-6

Notified classification and labelling according to CLP criteria
Classification Labelling Specific Concentration limits, M-Factors Notes Classification affected by Impurities / Additives

Additional Notified Information

Number of Notifiers

Joint Entries

Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Eye Irrit. 2; : 25 % ≤ C < 50 %
Note D
State/Form
12 yes View details
Acute Tox. 3 H311 H311
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Eye Dam. 1 H318  
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Respiratory sys...) (inhalation) H335
STOT RE 2 H373 (Liver, Kidney, ...) H373
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
Skin Corr. 1B; : C ≥ 50 %
Eye Irrit. 2; : 25 % ≤ C < 50 %
Skin Irrit. 2; : 25 % ≤ C < 50 %
Note D
State/Form
95 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
STOT RE 2 H373 (other:-) H373
STOT RE 2 H373 H373
Acute Tox. 3 H301 H301 GHS07
GHS08
GHS05
GHS06
Dgr
Skin Corr. 1B; : C ≥ 50 %
Skin Irrit. 2; : 25 % ≤ C < 50 %
Eye Irrit. 2; : 25 % ≤ C < 50 %
State/Form
87 View details
Acute Tox. 3 H311 H311
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Eye Dam. 1 H318 H318
Acute Tox. 3 H331 H331
STOT SE 3 H335 (Respiratory sys...) (inhalation) H335
STOT RE 2 H373 (Liver, Kidney, ...) H373
Acute Tox. 3 H301 H301 GHS08
Dgr
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Eye Irrit. 2; : 25 % ≤ C < 50 %
59 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
STOT RE 2 H373 (Not provided) H373
STOT RE 2 H373 (other:Not provi...) H373
Acute Tox. 3 H301   GHS08
GHS05
GHS06
Dgr
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Eye Irrit. 2; : 25 % ≤ C < 50 %
31 View details
  H301+H311+H331
Acute Tox. 3 H311  
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Eye Dam. 1 H318  
Acute Tox. 3 H331  
STOT SE 3 H335 (other:Respirato...) H335
STOT RE 2 H373 (other:Liver, Ki...) H373 (May cause damag...)
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Eye Irrit. 2; : 25 % ≤ C < 50 %
Note D
State/Form
25 View details
Acute Tox. 3 H311  
  H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Eye Dam. 1 H318  
Acute Tox. 3 H331 H331
STOT RE 2 H373 H373
Acute Tox. 3 H301   GHS08
GHS05
GHS06
Dgr
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Eye Irrit. 2; : 25 % ≤ C < 50 %
22 View details
  H301+H311+H331
Acute Tox. 3 H311  
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Eye Dam. 1 H318  
Acute Tox. 3 H331  
STOT SE 3 H335 (other:Respirato...) H335
STOT RE 2 H373 (other:Kidney, L...) H373 (May cause damag...)
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
Eye Irrit. 2; : 25 % ≤ C < 50 %
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Note D
State/Form
16 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
STOT RE 2 H373 H373
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
7 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
STOT RE 2 H373 (other:viscera) H373
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
Skin Corr. 1B; : C ca. 50 %
Eye Irrit. 2; : 25 % ca. C < 50 %
Skin Irrit. 2; : 25 % ca. C < 50 %
7 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
STOT RE 2 H373 (other:Several) H373
STOT RE 2 H373 (Several) H373
Acute Tox. 3 H301 H301 (H301) GHS08
GHS05
GHS06
Dgr
Note D
5 View details
Acute Tox. 4 H312 H312 (H312)
Skin Corr. 1B H314 H314 (H314)
Skin Sens. 1 H317 H317 (H317)
Acute Tox. 3 H331 H331 (H331)
STOT RE 2 H373 (Damage to Organ...) H373 (H373)
STOT RE 2 H373 (other:Damage to...) H373 (H373)
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
Eye Irrit. 2; : 25 % ≤ C < 50 %
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Note D
State/Form
3 View details
Acute Tox. 3 H311 H311
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Eye Dam. 1 H318  
Acute Tox. 3 H331 H331
STOT RE 2 H373 (other:-) H373
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
2 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
STOT RE 2 H373 (data lacking) H373
STOT RE 2 H373 (other:data lack...) H373
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
Eye Irrit. 2; : C ≥ 25 %
Skin Corr. 1B; : C ≥ 50 %
Skin Irrit. 2; : C ≥ 25 %
Note D
State/Form
2 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
STOT RE 2 H373 H373
Acute Tox. 3 H301   GHS08
GHS05
GHS06
Dgr
Eye Irrit. 2; : 25 % ≤ C < 50 %
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Note D
2 View details
  H301+H311+H331
Acute Tox. 3 H311  
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Eye Dam. 1 H318  
Acute Tox. 3 H331  
STOT RE 2 H373 (other:-) H373
Acute Tox. 3 H301 H301 GHS05
GHS06
Dgr
State/Form
1 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Eye Irrit. 2; : 25 % ≤ C < 50 %
Note D
yes State/Form
1 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
STOT RE 2 H373 H373
Acute Tox. 3 H301 H301 GHS08
GHS07
GHS05
GHS06
Dgr
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Eye Irrit. 2; : 25 % ≤ C < 50 %
1 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 2 H330 H330
STOT SE 3 H335 (other:respirato...) (inhalation) H335
STOT RE 2 H373 H373
Acute Tox. 3 H301 H301 GHS08
GHS07
GHS05
GHS06
Dgr
Eye Irrit. 2; : 25 % ≤ C < 50 %
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Eye Dam. 1; : 50 % ≤ C ca. 100 %
Note D
1 View details
Acute Tox. 3 H311 H311
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Eye Dam. 1 H318 H318
Acute Tox. 3 H331 H331
STOT SE 3 H335 (bronchioles,bro...) (inhalation) H335
STOT RE 2 H373 (other:-) H373
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Eye Irrit. 2; : 25 % ≤ C < 50 %
Note D
1 View details
Acute Tox. 3 H311 H311
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Eye Dam. 1 H318  
Acute Tox. 3 H331 H331
  H335
STOT RE 2 H373 (other:-) H373
Acute Tox. 3 H301 H301 GHS07
GHS08
GHS05
GHS06
Dgr
Skin Corr. 1B; : C ≥ 50 %
Eye Irrit. 2; : 25 % ≤ C < 50 %
Skin Irrit. 2; : 25 % ≤ C < 50 %
Note D
State/Form
1 View details
Acute Tox. 3 H311 H311
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
STOT RE 2 H373 (other:-) H373
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
State/Form
1 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
STOT RE 2 H373 (other:all organ...) H373
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
Skin Irrit. 2; : 25 % ≤ C < 50 %
Skin Corr. 1B; : C ≥ 50 %
Eye Irrit. 2; : 25 % ≤ C < 50 %
Note D
1 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
STOT RE 2 H373 (other:-) H373
Acute Tox. 3 H301 H301 GHS08
GHS05
GHS06
Dgr
State/Form
1 View details
Acute Tox. 4 H312 H312
Skin Corr. 1B H314 H314
Skin Sens. 1 H317 H317
Acute Tox. 3 H331 H331
STOT RE 2 H373 (dermal,inhalati...) H373

Number of Aggregated Notifications: 24