EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

Last updated 23 April 2024. Database contains 4691 unique substances/entries.

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Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU_BA Directive 2000/54/EC
4-nitrobiphenyl	202-204-7	92-93-3	Carc. 1B
4-nitrophenol; p-nitrophenol	202-811-7	100-02-7	Acute Tox. 4; STOT RE 2
4-nitrosoaniline	211-535-6	659-49-4	Acute Tox. 4
4-nitrosomorpholine	627-564-6	59-89-2	Carc. 1B; Muta. 2; STOT RE 1
4-nitrosophenol	203-251-6	104-91-6	Muta. 2; Acute Tox. 4; Eye Dam. 1
4-nitrotoluene	202-808-0	99-99-0	Acute Tox. 3; STOT RE 2
4-nonylphenol, branched	284-325-5	84852-15-3	Repr. 2; Acute Tox. 4; Skin Corr. 1B
4-nonylphenol, reaction products with formaldehyde and dodecane-1-thiol POLYSTAY K; WINGSTAY K	404-160-6	164907-73-7	Skin Sens. 1
4-o-tolylazo-o-toluidine; 4-amino-2',3-dimethylazobenzene; fast garnet GBC base; AAT; o-aminoazotoluene	202-591-2	97-56-3	Carc. 1B; Skin Sens. 1
4-oxo-4-(p-tolyl)butyric acid adduct with 4-ethylmorpholine	419-240-6	171054-89-0	Eye Dam. 1
4-phenylbut-1-ene 4-PHENYL-1-BUTENE; SQ 31,175; SQ31175	405-980-7	768-56-9	Skin Irrit. 2
4-propylcyclohexanone BICH-3 STUFE 3	406-810-4	40649-36-3	Skin Irrit. 2
4-tert-butylbenzoic acid	202-696-3	98-73-7	Repr. 1B; STOT RE 1; Acute Tox. 4
4-tert-butylphenol	202-679-0	98-54-4	Repr. 2; Skin Irrit. 2; Eye Dam. 1
4-vinylcyclohexene	202-848-9	100-40-3	Carc. 2
4-{[(6-chloropyridin-3-yl)methyl](2,2-difluoroethyl)amino}furan-2(5H)-one; flupyradifurone	804-373-8	951659-40-8	Acute Tox. 4; STOT RE 2
4H-3,1-benzoxazine-2,4(1H)-dione	204-255-0	118-48-9	Eye Irrit. 2; Skin Sens. 1
5(or 6)-tert-butyl-2'-chloro-6'-ethylamino-3',7'-dimethylspiro(isobenzofuran-1(1H),9'-xanthene)-3-one R-GELB 2454	400-680-2	98181-47-6	Acute Tox. 4
5,5-dimethyl-3-oxocyclohex-1-enyl dimethylcarbamate 5,5-dimethyldihydroresorcinol dimethylcarbamate; dimetan	204-525-8	122-15-6	Acute Tox. 3
5,5-dimethyl-perhydro-pyrimidin-2-one α-(4-trifluoromethylstyryl)-α-(4-trifluoromethyl)cinnamylidenehydrazone HYDRAMETHYLNON	405-090-9	67485-29-4	STOT RE 1; Acute Tox. 4; Eye Irrit. 2
5,6,12,13-tetrachloroanthra(2,1,9-def:6,5,10-d'e'f')diisoquinoline-1,3,8,10(2H,9H)-tetrone PIGMENTROT 1017; SUBSTANCE H112287	405-100-1	115662-06-1	Repr. 2
5,6-dihydro-3H-imidazo[2,1-c]-1,2,4-dithiazole-3-thione; etem	251-684-4	33813-20-6	Acute Tox. 4
5,6-dihydroxy-2,3-dihydro-1H-indolium bromide	421-170-6	138937-28-7	Acute Tox. 4; Eye Dam. 1
5,6-dihydroxyindole IMEXINE OAY	412-130-9	3131-52-0	Acute Tox. 4; Eye Dam. 1
5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine)-3-fluoro-2-hydroxymethyltetrahydrofuran 123U83; DDFU	415-360-8	41107-56-6	Muta. 2
5-(2-amino-5-cyano-6-[2-(2-hydroxyethoxy)ethylamino]-4-methylpyridin-3-ylazo)-3-methyl-2,4-dicarbonitrilethiophene	410-530-8	107815-88-3	Skin Sens. 1
5-(2-bromophenyl)-2-tert-butyl-2H-tetrazole WAY-128170	420-820-6	153042-18-3	Flam. Liq. 3; Acute Tox. 4
5-(3,6,9-trioxa-2-undecy loxy)benzo(d)-1,3-dioxolane; sesamex	-	51-14-9	Acute Tox. 4
5-(4-[4-[4-(3,5-dicarboxy-phenyl-azo)phenylamino]-6-morpholin-4-yl-1,3,5-triazin-2-ylamino]phenylazo)isophthalic acid, mixed monosodium and diammonium salt	414-410-6	1379676-83-1	Eye Dam. 1; Skin Sens. 1
5-[[4-chloro-6-[[2-[[4-fluoro-6-[[5-hydroxy-6-[(4-methoxy-2-sulfophenyl)azo]-7-sulfo-2-naphthalenyl]amino]-1,3,5-triazin-2-yl]amino]-1-methylethyl]amino]-1,3,5-triazin-2-yl]amino]-3-[[4-(ethenylsulfonyl)phenyl]azo]-4-hydroxy-naphtalene-2,7-disulfonic acid, sodium salt ROUGE REACTIF REN 208	418-380-5	168113-78-8	Eye Dam. 1
5-acetoxy-2-(R, S)butyryloxymethyl-1,3-oxathiolane	433-530-1	143446-73-5	Acute Tox. 4; Skin Sens. 1
5-acetyl-3-amino-10,11-dihydro-5H-dibenz[b, f]azepine-hydrochloride 5-ACETYL-3-AMINO-IMINODIBENZYL.HCL	410-490-1	138451-65-7	Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1
5-amino-2,4,6-triiodo-1,3-benzenedicarbonyldichloride ATIPACL	417-220-1	37441-29-5	Skin Sens. 1
5-amino-6-methyl-1,3-dihydrobenzoimidazol-2-one	428-410-9	67014-36-2	Acute Tox. 4; Skin Sens. 1
5-bromo-8-naphtholactam FAT 92'374	413-480-5	24856-00-6	Acute Tox. 4; Skin Sens. 1
5-chloro-1,3-dihydro-2H-indol-2-one CP-13,853	412-200-9	17630-75-0	Repr. 2; Acute Tox. 4; Skin Sens. 1
5-chloro-2,3-difluoropyridine CDFP	410-090-7	89402-43-7	Flam. Liq. 3; Acute Tox. 4
5-chloro-2-(4-chlorophenoxy)phenol	429-290-0	3380-30-1	Eye Dam. 1
5-endo-hexyl-bicyclo[2.2.1]hept-2-ene	435-000-3	22094-83-3	Asp. Tox. 1; Skin Irrit. 2
5-ethoxy-5H-furan-2-one	428-330-4	2833-30-9	Skin Corr. 1B; Acute Tox. 4; STOT RE 2; Skin Sens. 1
5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one	414-470-3	95885-13-5	Acute Tox. 4
5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide; 2'-[(RS)-1,3-dimethylbutyl]-5-fluoro-1,3-dimethylpyrazole-4-carboxanilide; penflufen	619-823-7	494793-67-8	Carc. 2
5-methylheptan-3-one	208-793-7	541-85-5	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
5-methylhexan-2-one; isoamyl methyl ketone	203-737-8	110-12-3	Flam. Liq. 3; Acute Tox. 4
5-methylpyrazine-2-carboxylic acid 5-METHYLPYRAZINE-2-CARBOXYLIC ACID; ACIDO 5-METILPIRAZIN CARBOSSILICO	413-260-9	5521-55-1	Eye Dam. 1
5-nitro-o-toluidine	202-765-8	99-55-8	Carc. 2; Acute Tox. 3
5-nitro-o-toluidine hydrochloride	256-960-8	51085-52-0	Carc. 2; Acute Tox. 3
5-nitroacenaphthene	210-025-0	602-87-9	Carc. 1B
5-tert-butyl-3-isoxazolylamine hydrochloride BISOX HCL	404-840-2	164578-13-6	Acute Tox. 4; STOT RE 2; Eye Dam. 1
5-thiazolylmethanol A-87440.0; A-87440.00	414-780-9	38585-74-9	Eye Dam. 1
5-{4-[5-amino-2-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-sulfo-phenylamino]-6-chloro-1,3,5-triazin-2-ylamino}-4-hydroxy-3-(1-sulfo-naphthalen-2-ylazo)-naphthalene-2,7-disulfonicacid sodium salt ROUGE TZ 4075	418-340-7	157707-94-3	Eye Dam. 1
6,13-dichloro-3,10-bis{2-[4-fluoro-6-(2-sulfophenylamino)-1,3,5-triazin-2-ylamino]propylamino}benzo[5,6][1,4]oxazino[2,3-.b.]phenoxazine-4,11-disulphonic acid, lithium-, sodium salt BLEU REN 20	418-000-8	163062-28-0	Eye Dam. 1
6,6'-bis(diazo-5,5', 6,6'-tetrahydro-5,5'-dioxo)[methylene-bis(5-(6-diazo-5,6-dihydro-5-oxo-1-naphthylsulphonyloxy)-6-methyl-2-phenylene]di(naphthalene-1-sulfonate)	441-550-5	-	Self-react. C; Carc. 2
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol; [DBMC]	204-327-1	119-47-1	Repr. 1B
6,7-dihydrodipyrido[1,2-α:2',1'- c]pyrazinediylium dihydroxide	301-467-6	94021-76-8	Acute Tox. 2; STOT RE 1; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
6-(1α,5aβ,8aβ,9-pentahydroxy-7β-isopropyl-2β,5β,8β-trimethylperhydro-8bα,9-epoxy-5,8-ethanocyclopenta[1,2-b]indenyl) pyrrole-2-carboxylate; ryania	239-732-2	15662-33-6	Acute Tox. 4
6-(2,3-dimethylmaleimido)hexyl methacrylate RONACAT RO 305; RONACOAT RO 305	404-870-6	63740-41-0	Skin Sens. 1
6-(nonylamino)-6-oxo-peroxyhexanoic acid ELFADOX EN 3001	406-680-9	104788-63-8	Org. Perox. C; Eye Dam. 1; Skin Sens. 1
6-(phthalimido)peroxyhexanoic acid PAP	410-850-8	128275-31-0	Org. Perox. D; Eye Dam. 1
6-[(C10-C13)-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid	701-118-1	2156592-54-8	Repr. 1B; Eye Irrit. 2
6-[C12-18-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid	701-162-1	-	Repr. 1B
6-[C12-18-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid, sodium and tris(2-hydroxyethyl)ammonium salts	701-271-4	-	Repr. 1B; Eye Irrit. 2
6-dimethylaminohexan-1-ol AF-507; M-3181	404-680-3	1862-07-3	Acute Tox. 4; Skin Corr. 1B
6-docosyloxy-1-hydroxy-4-(1-(4-hydroxy-3-methylphenanthren-1-yl)-3-oxo-2-oxaphenalen-1-yl)naphthalene-2-carboxylic acid ENS 131	404-550-6	130263-41-1	Skin Sens. 1
6-ethyl-5-fluoro-4(3H)-pyrimidone UK-103,442	422-460-5	137234-87-8	Acute Tox. 4
6-fluoro-2-methyl-3-(4-methylthiobenzyl)indene IN-4; INDENE IN-4	405-410-7	41201-60-9	Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
6-glycidyloxynapht-1-yl oxymethyloxirane	429-960-2	27610-48-6	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
6-hydroxy-1-(3-isopropoxypropyl)-4-methyl-2-oxo-5-[4-(phenylazo)phenylazo]-1,2-dihydro-3-pyridinecarbonitrile ARANCIO DISPERSO 149; C.I. DISPERSE ORANGE 149; DISPERS ORANGE 149; DISPERSE ORANGE 149; ORANGE DISPERSE 149; TERASIL GOLDGELB 2RS	400-340-3	85136-74-9	Carc. 1B
6-hydroxyindole IMEXINE OBA	417-020-4	2380-86-1	Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
6-methoxy-m-toluidine; p-cresidine	204-419-1	120-71-8	Carc. 1B; Acute Tox. 4
6-methyl-2,4-bis(methylthio)phenylene-1,3-diamine DM-C-TDA; DMTDA; ETHACURE (R) 300 CURATIVE	403-240-8	106264-79-3	Acute Tox. 4; Skin Sens. 1
6-phenyl-1,3,5-triazine-2,4- diyldiamine; 6-phenyl-1,3,5-triazine-2,4-diamine; benzoguanamine	202-095-6	91-76-9	Acute Tox. 4
7,7,9(or 7,9,9)-trimethyl-4,13-dioxo-3,14-dioxa-5,12-diazahexadecane-1,16-diyl bismethacrylate	276-957-5	72869-86-4	Skin Sens. 1B
7,7-dimethyl-3-oxa-6-azaoctan-1-ol FLEXSORB-SE	400-390-6	87787-67-5	Skin Corr. 1A; Acute Tox. 4
7-[((4,6-dichloro-1,3,5-triazin-2-yl)amino)-4-hydroxy-3-(4-((2-sulfoxy)ethyl)sulfonyl)phenylazo]naphthalene-2-sulfonic acid ORANGE BIREACTIVE DYE	407-050-6	117715-57-8	Skin Sens. 1
7-amino-3-((5-carboxymethyl-4- methyl-1,3-thiazol-2- ylthio)methyl)-8-oxo-5-thia-1- azabicyclo(4.2.0)oct-2-ene-2- carboxylic acid TACS	403-690-5	111298-82-9	Resp. Sens. 1; Skin Sens. 1
7-amino-4-hydroxy-2-naphthalenesulfonic acid, coupled with 5 (or 8) -amino-8 (or 5)-[[4-[[4-[[4-amino-6(or 7)-sulfo-1-naphthyl]azo]phenyl]amino]-3-sulfophenyl]azo]-2-naphthalenesulfonic acid and 4-hydroxy-7-(phenylamino)-2-naphthalenesulfonic acid, sodium salt	424-850-0	189702-72-5	Eye Dam. 1
7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid FLUORCHINOLONCARBONSÄURE	405-050-0	86393-33-1	Acute Tox. 4
7-methoxy-6-(3-morpholin-4-yl-propoxy)-3H-quinazolin-4-one [containing ≥ 0,5 % formamide (EC No 200-842-0)]	429-400-7	199327-61-2	Repr. 1B
7-methylocta-1,6-diene 7-METHYL-1,6-OCTADIENE	404-210-7	42152-47-6	Flam. Liq. 3
7-oxa-3-oxiranylbicyclo [4.1.0]heptane; 1,2-epoxy- 4-epoxyethylcyclohexane; 4-vinylcyclohexene diepoxide	203-437-7	106-87-6	Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 3; Acute Tox. 4
7a-ethyl-3,5-bis(1-methylethyl)-2,3,4,5-tetrahydrooxazolo[3,4-c]-2,3,4,5-tetrahydrooxazole ZOLDINE RD-20	417-140-7	79185-77-6	Skin Irrit. 2
8,8-dimethyl-7-isopropyl-6,10-dioxaspiro[4.5]decane OPALAL	424-030-2	62406-73-9	Skin Irrit. 2
8,9,10-trinorborn-2-yl acrylate	-	10027-06-2	Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
8,9,10-trinorborn-5-ene-2,3-dicarboxylic anhydride	204-957-7	129-64-6	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
8,9-dinorborn-5-ene-2,3-dicarboxylic anhydride	620-411-4	123748-85-6	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
8-amino-7-methylquinoline 8-AMINO-7-METHYLCHINOLIN	412-760-4	5470-82-6	Acute Tox. 4; Skin Sens. 1
8-azaspiro[4.5]decane-7,9-dione 3,3-TETRAMETHYLENE GLUTARIMIDE	427-770-4	1075-89-4	Acute Tox. 3
8-p-menthyl hydroperoxide; p-menthane hydroperoxide	201-281-4	80-47-7	Org. Perox. D; Skin Corr. 1B; Acute Tox. 4
9,9-bis(4-hydroxyphenyl)fluorene BPFL; FLUOREN-BIS-PHENOL	406-950-6	3236-71-3	Eye Irrit. 2; Skin Irrit. 2
9-(2-propenyloxy)tricyclo[5.2.1.0(2,6)]dec-3(or-4-)-ene FLEUROXENE	430-830-2	26912-64-1	Skin Irrit. 2
9-[2-(ethoxycarbonyl) phenyl]-3,6-bis(ethylamino)–2,7-dimethylxanthylium chloride; Basic Red 1	213-584-9	989-38-8	Acute Tox. 3; Eye Dam. 1; Skin Sens. 1
9-vinylcarbazole	216-055-0	1484-13-5	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
[(1-methyl-1,2-ethanediyl)bis[nitrilobis(methylene)]]tetrakis(phosphonic acid)	421-940-1	28698-31-9	Eye Dam. 1
[(4S, 5S)-4-benzyl-2-oxo-5-oxazolidinyl]methyl 4-nitrobenzenesulfonate	416-360-0	162221-28-5	Skin Sens. 1
[(dimethylsilylene)bis((1,2,3,3a,7a-η)-1H-inden-1-ylidene)dimethyl]hafnium M1	422-060-0	137390-08-0	Acute Tox. 2
[(m-tolyloxy)methyl]oxirane	218-575-3	2186-25-6	Muta. 2; Skin Irrit. 2; Skin Sens. 1
[(p-tolyloxy)methyl]oxirane	218-574-8	2186-24-5	Muta. 2; Skin Irrit. 2; Skin Sens. 1
[(tolyloxy)methyl]oxirane; cresyl glycidyl ether	247-711-4	26447-14-3	Muta. 2; Skin Irrit. 2; Skin Sens. 1
[1R-(1-α, 2β,5α)]-mono[5-methyl-2-(1-methylethyl)cyclohexyl]butanedioate	426-890-4	77341-67-4	Eye Dam. 1
[2-[(4-nitrophenyl)amino]ethyl]urea NITROGELB	410-700-1	27080-42-8	Skin Sens. 1
[3-(chlorocarbonyl)-2-methylphenyl]acetate	433-690-0	167678-46-8	Skin Corr. 1A; Skin Sens. 1
[[2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl] acetic acid	419-270-1	123599-82-6	Eye Irrit. 2
[carbonato(2-)] tetrahydroxytrinickel	235-715-9	12607-70-4	Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Acute Tox. 4; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
[N-(1,1-dimethylethyl)-1,1-dimethyl-1-[(1,2,3,4,5-η)-2,3,4,5-tetramethyl-2,4-cyclopentadien-1-yl]silanaminato(2-)-κN][(1,2,3,4-η)-1,3-pentadiene]-titanium	419-840-8	169104-71-6	Flam. Sol. 1; Skin Corr. 1B; Skin Sens. 1
[phosphinyldynetris(oxy)] tris[3-aminopropyl-2-hydroxy-N, N-dimethyl-N-(C6-18)-alkyl] trichlorides	425-520-9	197179-61-6	Eye Dam. 1
[R-(R,S)]-[[2-methyl-1-(1-oxopropoxy)propoxy]-(4-phenylbutyl)phosphinyl] acetic acid, (-)-cinchonidine (1:1) salt SQ 28,796	415-820-8	137590-32-0	Eye Dam. 1; Skin Sens. 1
[μ-[carbonato(2-)-O:O']]dihydroxy trinickel	265-748-4	65405-96-1	Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Acute Tox. 4; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
A reaction mass of: (1,3-dioxo-2H-benz(de)isoquinolin-2-ylpropyl)hexadecyldimethylammonium 4-toluenesulfonate; (1,3-dioxo-2H-benz(de)isoquinolin-2-ylpropyl)hexadecyldimethylammonium bromide CCA-VERSUCHSPRODUKT SN 4001	405-080-4	118725-24-9	Eye Dam. 1
abamectin (combination of avermectin B1a and avermectin B1b) (ISO)	615-339-5	71751-41-2	Repr. 2; Acute Tox. 2; Acute Tox. 1; STOT RE 1
Absettarov	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Absorption oils, bicyclo arom. and heterocyclic hydrocarbon fraction; Wash Oil Redistillate [A complex combination of hydrocarbons obtained as a redistillate from the distillation of wash oil. It consists predominantly of 2-ringed aromatic and heterocyclic hydrocarbons boiling in the range of approximately 260 °C to 290 °C (500°F to 554°F).] A complex combination of hydrocarbons obtained as a redistillate from the distillation of wash oil. It consists predominantly of 2-ringed aromatic and heterocyclic hydrocarbons boiling in the range of approximately 260°C to 290°C (500°F to 554°F).	309-851-5	101316-45-4	Carc. 1B
Acanthamoeba castellani	-	-		P Parasites
acephate (ISO); O, S-dimethyl acetylphosphoramidothioate	250-241-2	30560-19-1	Acute Tox. 4
acequinocyl (ISO); 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	611-595-7	57960-19-7	Skin Sens. 1; STOT SE 1; STOT RE 2
acetaldehyde; ethanal	200-836-8	75-07-0	Flam. Liq. 1; Carc. 1B; Muta. 2; Eye Irrit. 2; STOT SE 3
acetamide	200-473-5	60-35-5	Carc. 2
acetamiprid (ISO); (1E)-N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide; (E)-N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1-methylacetamidine	603-921-1	135410-20-7	Repr. 2; Acute Tox. 3
acetamiprid (ISO); (1E)-N-[(6-chloropyridin-3-yl)methyl]-N’-cyano-N-methylethanimidamide; (E)-N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1-methylacetamidine	682-791-8	160430-64-8	Repr. 2; Acute Tox. 3
acetic acid ... %	200-580-7	64-19-7	Flam. Liq. 3; Skin Corr. 1A
acetic acid;naphthalen-2-amine	209-030-0	553-00-4	Carc. 1A; Acute Tox. 4
acetic anhydride	203-564-8	108-24-7	Flam. Liq. 3; Acute Tox. 4; Skin Corr. 1B
acetochlor (ISO); 2-chloro-N-(ethoxymethyl)-N-(2-ethyl-6-methylphenyl)acetamide	251-899-3	34256-82-1	Carc. 2; Repr. 2; Acute Tox. 4; STOT SE 3; STOT RE 2; Skin Irrit. 2; Skin Sens. 1
acetone; propan-2-one; propanone	200-662-2	67-64-1	Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
acetonitrile; cyanomethane	200-835-2	75-05-8	Flam. Liq. 2; Acute Tox. 4; Eye Irrit. 2
acetophenone	202-708-7	98-86-2	Acute Tox. 4; Eye Irrit. 2
acetyl chloride	200-865-6	75-36-5	Flam. Liq. 2; Skin Corr. 1B
acetylene; ethyne	200-816-9	74-86-2	Flam. Gas 1; Press. Gas
acibenzolar-S-methyl; benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester CGA 245704 TECH.	420-050-0	135158-54-2	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
acifluorfen (ISO); 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoic acid	256-634-5	50594-66-6	Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
aclonifen (ISO); 2-chloro-6-nitro-3-phenoxyaniline	277-704-1	74070-46-5	Carc. 2; Skin Sens. 1A
aconitine	206-121-7	302-27-2	Acute Tox. 2
acrolein; prop-2-enal; acrylaldehyde	203-453-4	107-02-8	Flam. Liq. 2; Acute Tox. 1; Acute Tox. 2; Acute Tox. 3; Skin Corr. 1B
acrylamide; prop-2-enamide	201-173-7	79-06-1	Carc. 1B; Muta. 1B; Repr. 2; Acute Tox. 3; STOT RE 1; Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
acrylic acid, 3-(trimethoxysilyl)propyl ester	419-560-6	4369-14-6	Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
acrylic acid, monoester with propane-1,2-diol	247-118-0	25584-83-2	Acute Tox. 3; Skin Corr. 1B; Skin Sens. 1
acrylic acid; prop-2-enoic acid	201-177-9	79-10-7	Flam. Liq. 3; Acute Tox. 4; Skin Corr. 1A
acrylonitrile	203-466-5	107-13-1	Flam. Liq. 2; Carc. 1B; Acute Tox. 3; STOT SE 3; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
Actinomadura madurae	-	-		B Bacteria and similar species
Actinomadura pelletieri	-	-		B Bacteria and similar species
Actinomyces gerencseriae	-	-		B Bacteria and similar species
Actinomyces israelii	-	-		B Bacteria and similar species
Actinomyces pyogenes	-	-		B Bacteria and similar species
Actinomyces spp.	-	-		B Bacteria and similar species
Acute haemorrhagic conjunctivitis virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Adenoviridae	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Adinobacillus actinomycetemcomitans	-	-		B Bacteria and similar species
adipic acid	204-673-3	124-04-9	Eye Irrit. 2
alachlor (ISO); 2-chloro-2',6'-diethyl-N-(methoxymethyl)acetanilide	240-110-8	15972-60-8	Carc. 2; Acute Tox. 4; Skin Sens. 1
aldicarb (ISO); 2-methyl-2-(methylthio)propanal-O-(N-methylcarbamoyl)oxime	204-123-2	116-06-3	Acute Tox. 2; Acute Tox. 3
aldrin (ISO)	206-215-8	309-00-2	Carc. 2; Acute Tox. 3; STOT RE 1
alkali fluorosilicates(K)	240-896-2	16871-90-2	Acute Tox. 3
alkali fluorosilicates(Na)	240-934-8	16893-85-9	Acute Tox. 3
alkali fluorosilicates(NH4)	240-968-3	16919-19-0	Acute Tox. 3
alkali salts and alkali earth salts of thiocyanic acid, with the exception of those specified elsewhere in this Annex	-	-	Acute Tox. 4
Alkanes, C1-2; Petroleum gas	270-651-5	68475-57-0	Press. Gas; Flam. Gas 1; Carc. 1A; Muta. 1B
Alkanes, C1-4, C3-rich; Petroleum gas	292-456-4	90622-55-2	Press. Gas; Flam. Gas 1; Carc. 1A; Muta. 1B
alkanes, C10-13, chloro; chlorinated paraffins, C10-13	287-476-5	85535-84-8	Carc. 2
Alkanes, C12-26-branched and linear	292-454-3	90622-53-0	Carc. 1B
alkanes, C14-17, chloro; chlorinated paraffins, C14-17	287-477-0	85535-85-9	Lact.
Alkanes, C2-3; Petroleum gas	270-652-0	68475-58-1	Press. Gas; Flam. Gas 1; Carc. 1A; Muta. 1B
Alkanes, C3-4; petroleum gas	270-653-6	68475-59-2	Press. Gas; Flam. Gas 1; Carc. 1A; Muta. 1B
Alkanes, C4-5; Petroleum gas	270-654-1	68475-60-5	Press. Gas; Flam. Gas 1; Carc. 1A; Muta. 1B
alkenes, C12-14, hydroformylation products, distn. residues, C-(hydrogen sulfobutanedioates), disodium salts	435-660-2	243662-67-1	Skin Irrit. 2; Skin Sens. 1
alkyl(rapeseed oil), bis(2-hydroxyethyl)ammonium fluoride	435-650-8	-	Acute Tox. 4; Skin Corr. 1A
allethrin; (RS)-3-allyl-2-methyl-4-oxocyclopent-2-enyl (1RS,3RS;1RS,3SR)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate; bioallethrin; (RS)-3-allyl-2-methyl-4-oxocyclopent-2-enyl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate;esbiothrin; (RS)-3-allyl-2-methyl-4-oxocyclopent-2-enyl(1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate	209-542-4	584-79-2;84030-86-4	Acute Tox. 4
allethrin; (RS)-3-allyl-2-methyl-4-oxocyclopent-2-enyl (1RS,3RS;1RS,3SR)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate; bioallethrin; (RS)-3-allyl-2-methyl-4-oxocyclopent-2-enyl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate;esbiothrin; (RS)-3-allyl-2-methyl-4-oxocyclopent-2-enyl(1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate	209-542-4	584-79-2;84030-86-4	Acute Tox. 4
allidochlor (ISO); N,N-diallylchloroacetamide	202-270-7	93-71-0	Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
allyl alcohol	203-470-7	107-18-6	Flam. Liq. 2; Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
allyl glycidyl ether; allyl 2,3-epoxypropyl ether; prop-2-en-1-yl 2,3-epoxypropyl ether	203-442-4	106-92-3	Flam. Liq. 3; Carc. 2; Muta. 2; Repr. 2; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
allyl methacrylate; 2-methyl-2-propenoic acid 2-propenyl ester	202-473-0	96-05-9	Flam. Liq. 3; Acute Tox. 2; Acute Tox. 3; Acute Tox. 4
allylamine	203-463-9	107-11-9	Flam. Liq. 2; Acute Tox. 3
aluminium alkyls	-	-	Pyr. Liq. 1; Water-react. 1; Skin Corr. 1B
aluminium chloride, anhydrous	231-208-1	7446-70-0	Skin Corr. 1B
aluminium lithium hydride	240-877-9	16853-85-3	Water-react. 1; Skin Corr. 1A
aluminium phosphide	244-088-0	20859-73-8	Water-react. 1; Acute Tox. 2; Acute Tox. 3; Acute Tox. 1
aluminium powder (pyrophoric);aluminium powder (stabilised)	231-072-3	7429-90-5	Water-react. 2; Flam. Sol. 1
aluminium powder (pyrophoric);aluminium powder (stabilised)	231-072-3	7429-90-5	Water-react. 2; Pyr. Sol. 1
aluminium-tri-isopropoxide	209-090-8	555-31-7	Flam. Sol. 1
ametryn (ISO);N-ethyl-N'-isopropyl-6-(methyl-thio)-1,3,5-triazine-2,4-diamine	212-634-7	834-12-8	Acute Tox. 4
amidithion (ISO); 2-methoxyethylcarbamoylmethyl O,O-dimethyl phosphorodithioate	-	919-76-6	Acute Tox. 4
amines, coco alkyl	262-977-1	61788-46-3	Acute Tox. 4; Asp. Tox. 1; STOT SE 3; STOT RE 2; Skin Corr. 1B
amines, hydrogenated tallow alkyl	262-976-6	61788-45-2	Asp. Tox. 1; STOT RE 2; Skin Irrit. 2; Eye Dam. 1
amines, polyethylenepoly-; HEPA;polyethlyenepolyamines with the exception of those specified elsewhere in this Annex	268-626-9	68131-73-7	Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
amines, polyethylenepoly-; HEPA;polyethlyenepolyamines with the exception of those specified elsewhere in this Annex	268-626-9	68131-73-7	Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
amines, tallow alkyl	263-125-1	61790-33-8	Acute Tox. 4; Asp. Tox. 1; STOT RE 2; Skin Corr. 1B
aminocarb (ISO); 4-dimethylamino-3-tolyl methylcarbamate	217-990-7	2032-59-9	Acute Tox. 3
amisulbrom (ISO); 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamide	672-776-4	348635-87-0	Carc. 2; Eye Irrit. 2
amitraz (ISO); N,N-bis(2,4-xylyliminomethyl); methylamine	251-375-4	33089-61-1	Acute Tox. 4; STOT RE 2; Skin Sens. 1
amitrole (ISO);1,2,4-triazol-3-ylamine	200-521-5	61-82-5	Repr. 2; STOT RE 2
ammonia ... %	215-647-6	1336-21-6	Skin Corr. 1B
ammonia, anhydrous	231-635-3	7664-41-7	Flam. Gas 2; Press. Gas; Acute Tox. 3; Skin Corr. 1B
ammonium (Z)-α-methoxyimino-2-furylacetate 640 AMMONIUM SALT; KSMIA; S-102; SMIA	405-990-1	97148-39-5	Flam. Sol. 1
ammonium 2-cocoyloxyethanesulfonate	441-050-7	223705-57-5	Skin Irrit. 2; Eye Dam. 1
ammonium bifluoride; ammonium hydrogen difluoride	215-676-4	1341-49-7	Acute Tox. 3; Skin Corr. 1B
ammonium bis(1-(3,5-dinitro-2-oxidophenylazo)-3-(N-phenylcarbamoyl)-2-naphtholato)chromate(1-) AIZEN SPILON BLACK TRH; AIZEN SPILON SCHWARZ TRH; THR-1; TRH	400-110-2	109125-51-1	Self-react. C
ammonium bromide	235-183-8	12124-97-9	Repr. 1B; Lact.; STOT SE 3; STOT RE 1; Eye Irrit. 2
ammonium chloride	235-186-4	12125-02-9	Acute Tox. 4; Eye Irrit. 2
ammonium dichromate	232-143-1	7789-09-5	Ox. Sol. 2; Carc. 1B; Muta. 1B; Repr. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Acute Tox. 4; Skin Corr. 1B; Resp. Sens. 1; Skin Sens. 1
ammonium fluoride	235-185-9	12125-01-8	Acute Tox. 3

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EU-SAFETY_HEALTH_WORK-PREAMBLE

EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

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Last updated 23 April 2024. Database contains 4691 unique substances/entries.

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