EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

Last updated 23 April 2024. Database contains 4691 unique substances/entries.

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Showing 1,701 - 1,800 of 4,691 results.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU_BA Directive 2000/54/EC
methyl 3-amino-4,6-dibromo-2-methyl-benzoate	425-190-6	119916-05-1	STOT RE 2
methyl 3-amino-2,2,3-trimethylbutyrate	431-720-7	90886-53-6	Skin Corr. 1B; Acute Tox. 4
methyl 3-[(dimethoxyphosphinothioyl)oxy]methacrylate	250-366-2	30864-28-9	Acute Tox. 4; Skin Sens. 1
methyl 3-(acetylthio)-2-methyl-propanoate D,L-ESTER	411-040-7	97101-46-7	Acute Tox. 4; Skin Sens. 1
methyl 3-(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate G 18-1108	403-270-1	6386-39-6	Acute Tox. 4
methyl 3,4-dichlorophenylcarbanilate; SWEP.	620-362-9	1918-18-9	Acute Tox. 4
methyl 2R,3S-(-)-3-(4-methoxyphenyl)oxiranecarboxylate MEFAT	404-130-2	105560-93-8	Eye Dam. 1; Skin Sens. 1
methyl 2-chlorosulfonyl-4-(methanesulfonylaminomethyl) benzoate	443-120-2	393509-79-0	Eye Dam. 1
methyl 2-benzylidene-3-oxobutyrate LUGALVAN ES 9571	420-940-9	15768-07-7	Eye Irrit. 2; Skin Irrit. 2
methyl 2-aminosulfonyl-6-(trifluoromethyl)pyridine-3-c arboxylate JE 127	421-220-7	144740-59-0	Skin Sens. 1
methyl 2-[4-(2-chloro-4-nitrophenylazo)-3-(1-oxopropyl)amino]phenylaminopropionate DISPERSE RED CLA 282	416-240-8	155522-12-6	Skin Sens. 1
methyl 2-(acetylamino)-3-chloropropionate	442-860-3	87333-22-0	Skin Sens. 1
methyl 2-(3-nitrobenzylidene)acetoacetate BM	405-270-7	39562-17-9	Skin Sens. 1
methyl 2-(2-nitrobenzylidene)acetoacetate 2-NITROBENZYLIDENE METHYL ESTER; BAY O 2787	400-650-9	39562-27-1	Skin Sens. 1
methyl 2,5-dichlorobenzoate	220-815-7	2905-69-3	Acute Tox. 4; STOT SE 3
methyl 2,2-dimethyl-6-methylenecyclohexanecarboxylate	432-350-9	81752-87-6	Skin Irrit. 2
methyl (±)-lactate;methyl lactate	208-930-0	2155-30-8;547-64-8	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
methyl (±)-lactate;methyl lactate	208-930-0	2155-30-8;547-64-8	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
methyl (S)-(-)-lactate	248-704-9	27871-49-4	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
methyl (R)-lactate	241-420-6	17392-83-5	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
methyl (R)-2-(4-hydroxyphenoxy)propionate DHPPME; MAK-ME; MEHPOPS; R-MAQ-ME	411-950-4	96562-58-2	Eye Dam. 1
methyl (R)-2-(4-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenoxy)propionate HALOXYFOP R-(+)-ME HERBICIDAL CHEMICAL	406-250-0	72619-32-0	Acute Tox. 4
methyl (9-acetoxy-3,8,10-triethyl-7,8,10-trimethyl-1,5-dioxa-9-aza-spiro[5.5]undec-3-yl)octadecanoate	445-990-9	376588-17-9	Skin Sens. 1
methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate GR138766X	415-670-3	78850-37-0	Eye Dam. 1
methoxyacetic acid	210-894-6	625-45-6	Repr. 1B; Acute Tox. 4; Skin Corr. 1B
methomyl (ISO); 1-(methylthio)ethylideneamino N-methylcarbamate	240-815-0	16752-77-5	Acute Tox. 2
methidathion (ISO); 2,3-dihydro-5-methoxy-2-oxo-1,3,4-thiadiazol-3-ylmethyl-O,O-dimethylphosphorodithioate	213-449-4	950-37-8	Acute Tox. 2; Acute Tox. 4
methenamine; hexamethylenetetramine	202-905-8	100-97-0	Flam. Sol. 2; Skin Sens. 1
methanol	200-659-6	67-56-1	Flam. Liq. 2; Acute Tox. 3; STOT SE 1
methanethiol; methyl mercaptan	200-822-1	74-93-1	Flam. Gas 1; Press. Gas; Acute Tox. 3
methanesulphonic acid	200-898-6	75-75-2	Skin Corr. 1B
methane	200-812-7	74-82-8	Flam. Gas 1; Press. Gas
methamidophos (ISO); O,S-dimethyl phosphoramidothioate	233-606-0	10265-92-6	Acute Tox. 2; Acute Tox. 3
methacrylonitrile; 2-methyl-2-propene nitrile	204-817-5	126-98-7	Flam. Liq. 2; Acute Tox. 3; Skin Sens. 1
methacrylic acid; 2-methylpropenoic acid	201-204-4	79-41-4	Acute Tox. 4; Skin Corr. 1A
methacrifos (ISO); methyl (E)-3-[(dimethoxyphosphinothioyl)oxy]methacrylate	630-448-8	62610-77-9	Acute Tox. 4; Skin Sens. 1
metconazole (ISO); (1RS, 5RS;1RS, 5SR)-5-(4-chlorobenzyl)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	603-031-3	125116-23-6	Repr. 2; Acute Tox. 4
metazachlor (ISO); 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)-acetamide	266-583-0	67129-08-2	Skin Sens. 1B; Carc. 2
metamitron (ISO);4-amino-3-methyl-6-phenyl-1,2,4-triazin-5-one	255-349-3	41394-05-2	Acute Tox. 4
metam-sodium (ISO); sodium methyldithiocarbamate	205-293-0	137-42-8	Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
metalaxyl-M (ISO); mefenoxam; (R)-2-[(2,6-dimethylphenyl)-methoxyacetylamino]propionic acid methyl ester	615-135-6	70630-17-0	Acute Tox. 4; Eye Dam. 1
metalaxyl (ISO); methyl-N-(2,6-dimethylphenyl)-N-(methoxyacetyl)-DL-alaninate	260-979-7	57837-19-1	Acute Tox. 4; Skin Sens. 1
metal salts of thiocyanic acid, with the exception of those specified elsewhere in this Annex	-	-	Acute Tox. 4
metaflumizone (ISO); (EZ)-2-[2-(4-cyanophe-nyl)-1-(a,a,a -trifluoro-m-tolyl)ethylidene]-[4-(tri-fluoromethoxy)phenyl] carbanilohydrazide [E-iso-mer > 90 %, Z-isomer <10 % relative content]	604-167-6	139968-49-3	Repr. 2; Lact.; STOT RE 2
metaflumizone (ISO); (E)-2-[2-(4-cyanophenyl)-1-(a,a,a -trifluoro-m-tolyl) ethylidene]-[4-(trifluoro-methoxy)phenyl]carbani-lohydrazide [2]	701-454-9	852403-68-0	Repr. 2; Lact.; STOT RE 2
mesotrione(ISO); 2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione	600-533-4	104206-82-8	Repr. 2; STOT RE 2
mesitylene; 1,3,5-trimethylbenzene	203-604-4	108-67-8	Flam. Liq. 3; STOT SE 3
mercury difulminate; mercuric fulminate; fulminate of mercury;mercury difulminate; mercuric fulminate; fulminate of mercury [≥ 20 % phlegmatiser]	211-057-8	628-86-4	Expl. 1.1; Acute Tox. 3; STOT RE 2
mercury difulminate; mercuric fulminate; fulminate of mercury;mercury difulminate; mercuric fulminate; fulminate of mercury [≥ 20 % phlegmatiser]	211-057-8	628-86-4	Unst. Expl.; Acute Tox. 3; STOT RE 2
mercury dichloride; mercuric chloride	231-299-8	7487-94-7	Muta. 2; Repr. 2; Acute Tox. 2; STOT RE 1; Skin Corr. 1B
mercury	231-106-7	7439-97-6	Repr. 1B; Acute Tox. 2; STOT RE 1
mercaptodimethur (ISO); methiocarb (ISO); 3,5-dimethyl-4-methylthiophenyl N-methylcarbamate	217-991-2	2032-65-7	Acute Tox. 3
mequinol; 4-methoxyphenol; hydroquinone monomethyl ether	205-769-8	150-76-5	Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
mepiquat chloride (ISO); 1,1-dimethylpiperidinium chloride	246-147-6	24307-26-4	Acute Tox. 4; Acute Tox. 3
mephosfolan (ISO); diethyl 4-methyl-1,3-dithiolan-2-ylidenephosphoramidate	213-447-3	950-10-7	Acute Tox. 1; Acute Tox. 2
mepanipyrim; 4-methyl-N-phenyl-6-(1-propynyl)-2-pyrimidinamine	432-140-7	110235-47-7	Carc. 2
menazon (ISO); S-[(4,6-diamino-1,3,5-triazin-2-yl)methyl] O, O-dimethyl phosphorodithioate	201-123-4	78-57-9	Acute Tox. 4
menadione sodium bisulfite; 2-naphthalenesulfonic acid,1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, sodium salt	204-987-0	130-37-0	Eye Irrit. 2; Skin Irrit. 2
menadione nicotinamide bisulfite; 1,2,3,4-tetrahydro-2-methyl-1,4-dioxonaphthalene-2-sulfonicacid, compound with nicotin-3-amide (1:1)	277-543-7	73581-79-0	Eye Irrit. 2; Skin Irrit. 2
medinoterb acetate (ISO); 6-tert-butyl-3-methyl-2,4-dinitrophenyl acetate	219-634-6	2487-01-6	Acute Tox. 3; Acute Tox. 4
mecrilate; methyl 2-cyanoacrylate	205-275-2	137-05-3	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
mecoprop-P (ISO) and its salts; (R)-2-(4-chloro-2-methylphenoxy) propionic acid and its salts	-	-	Acute Tox. 4; Eye Dam. 1
mecetronium etilsulfate; N-ethyl-N,N-dimethylhexadecan-1-aminium ethyl sulfate; mecetronium ethyl sulphate; [MES]	221-106-5	3006-10-8	Skin Corr. 1; Eye Dam. 1
mecarbam (ISO); N-ethoxycarbonyl-N-methylcarbamoylmethyl O, O-diethyl phosphorodithioate	219-993-9	2595-54-2	Acute Tox. 3
Measles virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
MCPA-thioethyl (ISO); S-ethyl (4-chloro-2-methylphenoxy)ethanethioate; S-ethyl 4-chloro-o-tolyloxythioacetate	246-831-4	25319-90-8	Acute Tox. 4
MCPA (ISO); 4-chloro-o-tolyloxyacetic acid	202-360-6	94-74-6	Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
Mayaro virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Margosa, ext. [from the kernels of Azadirachta indica extracted with water and further processed with organic solvents] Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Azadirachta indica, Meliaceae.	283-644-7	84696-25-3	Repr. 2; Skin Sens. 1
Marburg virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Mansonella perstans	-	-		P Parasites
Mansonella ozzardi	-	-		P Parasites
mannitol hexanitrate; nitromannite;mannitol hexanitrate; nitromannite;[>40 % phlegmatiser]	239-924-6	15825-70-4	Expl. 1.1
mannitol hexanitrate; nitromannite;mannitol hexanitrate; nitromannite;[>40 % phlegmatiser]	239-924-6	15825-70-4	Unst. Expl.
manganese sulphate	232-089-9	7785-87-7	STOT RE 2
manganese dioxide	215-202-6	1313-13-9	Acute Tox. 4
maneb (ISO); manganese ethylenebis(dithiocarbamate) (polymeric)	235-654-8	12427-38-2	Repr. 2; Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
mancozeb (ISO); manganese ethylenebis(dithiocarbamate) (polymeric) complex with zinc salt	616-995-5	8018-01-7	Carc. 2; Repr. 1B; STOT RE 2; Skin Sens. 1
malononitrile	203-703-2	109-77-3	Acute Tox. 3
maleic anhydride	203-571-6	108-31-6	Acute Tox. 4; STOT RE 1; Skin Corr. 1B; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1A
maleic acid	203-742-5	110-16-7	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
malathion (ISO); 1,2-bis(ethoxycarbonyl)ethyl O, O-dimethyl phosphorodithioate [containing ≤ 0,03 % isomalathion]	204-497-7	121-75-5	Acute Tox. 4; Skin Sens. 1
malachite green oxalate	219-441-7	2437-29-8	Repr. 2; Acute Tox. 4; Eye Dam. 1
malachite green hydrochloride	209-322-8	569-64-2	Repr. 2; Acute Tox. 4; Eye Dam. 1
Main component: acetoacetic acid anilide/3-amino-1-hydroxybenzene (ATAN-MAP): trisodium {6-[(2 or 3 or 4)-amino-(4 or 5 or 6)-hydroxyphenylazo]-5'-(phenylsulfamoyl)-3-sulfonatonaphthalene-2-azobenzene-1,2'-diolato}-{6''-[1-(phenylcarbamoyl)ethylazo]-5'-(phenylsulfamoyl)-3-sulfonatonaphthalene-2''-azobenzene-1'',2'''-diolato}chromate (III); by-product 1: acetoacetic acid anilide/acetoacetic acid anilide (ATAN-ATAN): trisodium bis{6-[1-(phenylcarbamoyl)ethylazo]-5'''-(phenylsulfonyl)-3''-sulfonatonaphthalene-2-azobenzene-1,2'-diolato}chromate (III); by-product 2: 3-amino-1-hydroxybenzene/3-amino-1-hydroxybenzene (MAP-MAP): trisodium bis{6-[(2 or 3 or 4)-amino-(4 or 5 or 6)-hydroxyphenylazo]-5'-(phenylsulfamoyl)-3-sulfonatonaphthalene-2-azobenzene-1,2'-diolato}chromate (III) BLACK JR 578	419-230-1	-	Skin Sens. 1
main component 6 (isomer): asym. 1:2 Cr(III)-complex of: A: 3-hydroxy-4-(2-hydroxy-naphthalene-1-ylazo)naphthalene-1-sulfonic acid, Na-salt and B: 1-[2-hydroxy-5-(4-methoxy-phenylazo)phenylazo]naphthalene-2-ol; main component 8 (isomer):; asym. 1:2 Cr-complex of: A:; 3-hydroxy-4-(2-hydroxy-naphthalene-1-ylazo)-naphthalene-1-sulfonic acid, Na-salt and B: 1-[2-hydroxy-5-(4-methoxy-phenylazo)-phenylazo]-naphthalene-2-ol BLACK UL 1253	417-280-9	30785-74-1	Eye Dam. 1
main component 1 (isomer 1):; 2-{6-fluoro-4-[3-(2,5-disulfo-phenylazo)-4-hydroxy-2-sulfonapht-7-ylamino]-1,3,5-triazin-2-ylamino}-3-{6-fluoro-4-[3-(1,5-disulfonaphth-2-ylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-propane sodium salt; main component 1 (isomer 2):; 2-{6-fluoro-4-[3-(2,5-disulfophenylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-3-{6-fluoro-4-[3(2,5-disulfo-phenylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-propane sodium salt; main component 2: 2,3-bis-{6-fluoro-4-[3-(2,5-disulfo-phenylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-propane sodium salt; main component 3: 2,3-bis-{6-fluoro-4-[3-(1,5-disulfonaphth-2-ylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-propane sodium salt	422-610-1	-	Eye Dam. 1
magnesium sodium fluoride silicate	442-650-1	56450-90-9	STOT RE 2
magnesium powder (pyrophoric);magnesium, powder or turnings	231-104-6	7439-95-4	Flam. Sol. 1; Water-react. 2; Self-heat. 1
magnesium powder (pyrophoric);magnesium, powder or turnings	231-104-6	7439-95-4	Water-react. 1; Pyr. Sol. 1
magnesium phosphide; trimagnesium diphosphide	235-023-7	12057-74-8	Water-react. 1; Acute Tox. 2; Acute Tox. 3; Acute Tox. 1
magnesium hexafluorosilicate	241-022-2	16949-65-8	Acute Tox. 3
magnesium bis((R)-2-(2,4-dichlorophenoxy)propionate) DUPLOSAN-DP-MAGNESIUM	413-360-2	164058-21-3	Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
magnesium alkyls	-	-	Pyr. Liq. 1; Water-react. 1; Skin Corr. 1B
Madurella mycetomatis	-	-		F Fungi
Madurella grisea	-	-		F Fungi
Machupo virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
m-xylene	203-576-3	108-38-3	Flam. Liq. 3; Acute Tox. 4; Skin Irrit. 2
m-tolylidene diisocyanate; toluene-diisocyanate	247-722-4	26471-62-5	Carc. 2; Acute Tox. 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
m-toluidine; 3-aminotoluene	203-583-1	108-44-1	Acute Tox. 3; STOT RE 2

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EU-SAFETY_HEALTH_WORK-PREAMBLE

EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

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Last updated 23 April 2024. Database contains 4691 unique substances/entries.

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