EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

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Last updated 18 April 2024. Database contains 4691 unique substances/entries.
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Substance Name
EC No.
CAS No.
EU CLP (1272/2008)
EU_BA Directive 2000/54/EC
2-aminoethyldimethylamine; 2-dimethylaminoethylamine
203-541-2
108-00-9
Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1A
2-aminophenol
202-431-1
95-55-6
Muta. 2; Acute Tox. 4
2-aminopropane; isopropylamine
200-860-9
75-31-0
Flam. Liq. 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
2-aminosulfonyl-N, N-dimethylnicotinamide
DAM 520
413-440-7
112006-75-4
Skin Sens. 1
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
CG 25-369; IRGACURE 369; TK 11-319
404-360-3
119313-12-1
Repr. 1B
2-benzyl-2-methyl-3-butenitrile
CITROWANIL B
407-870-4
97384-48-0
Acute Tox. 4
2-bromo-1-(2-furyl)-2-nitroethylene
EF-40
406-110-9
35950-52-8
Acute Tox. 4; STOT RE 2; Skin Corr. 1B; Skin Sens. 1
2-bromo-2-nitropropanol
DEBROPOL
407-030-7
24403-04-1
Acute Tox. 3; Acute Tox. 4; STOT RE 2; Skin Corr. 1B; Skin Sens. 1
2-bromo-4,6-difluoroaniline
429-430-0
444-14-4
Acute Tox. 4
2-bromo-5-hydroxy-4-methoxybenzaldehyde
426-540-0
2973-59-3
Skin Sens. 1
2-bromomalonaldehyde
430-470-6
2065-75-0
Acute Tox. 4; Eye Dam. 1
2-bromopropane
200-855-1
75-26-3
Flam. Liq. 2; Repr. 1A; STOT RE 2
2-butanone-O, O',O''-(phenylsilylidyne)trioxime
433-360-6
34036-80-1
STOT RE 2; Skin Sens. 1
2-butoxyethanol; ethylene glycol monobutyl ether
203-905-0
111-76-2
Acute Tox. 3; Acute Tox. 4; Skin Irrit. 2; Eye Irrit. 2
2-butoxyethyl acetate; butylglycol acetate
203-933-3
112-07-2
Acute Tox. 4
2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride
SR 48001 A
424-560-4
151257-01-1
Acute Tox. 4; Eye Irrit. 2
2-butyl-2-ethyl-1,5-diaminopentane
C11-NEODIAMINE
412-700-7
137605-95-9
Acute Tox. 4; STOT RE 2; Skin Corr. 1B; Skin Sens. 1
2-butyl-4-chloro-5-formylimidazole
2-BUTYL-4-CHLORO-5-FORMYLIMIDAZOLE; BCFI
410-260-0
83857-96-9
Skin Sens. 1
2-butyryl-3-hydroxy-5-thiocyclohexan-3-yl-cyclohex-2-en-1-one
425-150-8
94723-86-1
Repr. 1B; Acute Tox. 4; Skin Sens. 1
2-chloracetamide
201-174-2
79-07-2
Repr. 2; Acute Tox. 3; Skin Sens. 1
2-chloro-1,3,5-trinitrobenzene
201-864-3
88-88-0
Expl. 1.1; Acute Tox. 2; Acute Tox. 1
2-chloro-3-trifluoromethylpyridine
424-520-6
65753-47-1
Acute Tox. 3; STOT RE 1; Skin Corr. 1B
2-chloro-4,5-difluorobenzoic acid
2-CHLORO-4,5-DIFLUORO BENZOIC ACID; BA-6; CDFBA
405-380-5
110877-64-0
Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
2-chloro-4-(methylsulfonyl)benzoic acid
2-CHLOR-4-METHYLSULFONYLBENZOESÄURE; CMSBA
406-520-8
53250-83-2
Eye Dam. 1
2-chloro-4-fluoro-5-nitrophenyl(isobutyl)carbonate
427-020-6
141772-37-4
STOT RE 2; Skin Sens. 1
2-chloro-4-nitroaniline
204-502-2
121-87-9
Acute Tox. 4
2-chloro-5-chloromethylthiazole
2-CHLORO-5-CHLOROMETHYLTHIAZOLE
429-830-5
105827-91-6
Acute Tox. 3; Skin Corr. 1B; Acute Tox. 4; Skin Sens. 1
2-chloro-5-methyl-pyridine
2-CHLORO-5-METHYLPYRIDINE; CMP
418-050-0
18368-64-4
Acute Tox. 4; Skin Irrit. 2
2-chloro-5-sec-hexadecylhydroquinone
AF-377
407-750-1
137193-60-3
Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
2-chloro-6-(ethylamino)-4-nitrophenol
ROT CO
411-440-1
131657-78-8
Acute Tox. 4; Skin Sens. 1
2-chloro-6-fluoro-phenol
433-890-8
2040-90-6
Muta. 1B; Repr. 2; Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
2-chloro-N-(4-methylphenyl)acetamide
435-170-9
16634-82-5
Eye Dam. 1; Skin Sens. 1
2-chloro-p-toluenesulfochloride
2-CHLOR-4-TOLUOLSULFONYLCHLORID
412-890-1
42413-03-6
Skin Corr. 1B; Skin Sens. 1
2-chlorobenzaldehyde; o-chlorobenzaldehyde
201-956-3
89-98-5
Skin Corr. 1B
2-chlorobenzonitrile
212-836-5
873-32-5
Acute Tox. 4; Eye Irrit. 2
2-chloroethanol; ethylene chlorohydrin
203-459-7
107-07-3
Acute Tox. 2; Acute Tox. 1
2-chloromethyl-3,4-dimethoxypyridinium chloride
B8510-020; CHLORMETHYLPYRIDIN; CHLORMETHYLPYRIDINE; CHLOROMETHYLPYRIDINE
416-440-5
72830-09-2
Acute Tox. 4; STOT RE 2; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
2-chloropentane
210-885-7
625-29-6
Flam. Liq. 2; Acute Tox. 4
2-chlorophenol
202-433-2
95-57-8
Acute Tox. 4
2-chloropropane
200-858-8
75-29-6
Flam. Liq. 2; Acute Tox. 4
2-chloropropionic acid
209-952-3
598-78-7
Acute Tox. 4; Skin Corr. 1A
2-chlorotoluene
202-424-3
95-49-8
Acute Tox. 4
2-cyclohexylidene-2-phenylacetonitrile
423-740-1
10461-98-0
Acute Tox. 4
2-cyclohexylpropanal
POLLENAL II
412-270-0
2109-22-0
Skin Sens. 1
2-cyclopentene-1-acetic acid, 3-hydroxy-2-pentyl-, methyl ester acetate
431-400-7
57374-49-9
Skin Sens. 1
2-cyclopentylidene cyclopentanol 1,1'-bi(cyclopentyliden)-2-ol
434-270-1
6261-30-9
Skin Irrit. 2; Eye Dam. 1
2-diethylaminoethanol; N,N-diethylethanolamine
202-845-2
100-37-8
Flam. Liq. 3; Acute Tox. 4; Skin Corr. 1B
2-diethylaminoethyl methacrylate
203-275-7
105-16-8
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
2-dimethylaminoethanol; N,N-dimethylethanolamine
203-542-8
108-01-0
Flam. Liq. 3; Acute Tox. 4; Skin Corr. 1B
2-dimethylaminoethyl methacrylate
220-688-8
2867-47-2
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
2-ethoxy-1-methylethyl acetate; 2PG1EEA
259-370-9
54839-24-6
Flam. Liq. 3; STOT SE 3
2-ethoxyaniline; o-phenetidine
202-356-4
94-70-2
Acute Tox. 3; STOT RE 2
2-ethoxyethanol; ethylene glycol monoethyl ether
203-804-1
110-80-5
Flam. Liq. 3; Repr. 1B; Acute Tox. 3; Acute Tox. 4
2-ethoxyethyl 2-(4-(2,6-dihydro-2,6-dioxo-7-phenyl-1,5-dioxaindacen-3-yl)phenoxy)acetate
C.I. DISPERSE RED 367
403-960-2
147014-52-6
Skin Sens. 1
2-ethoxyethyl acetate; ethylglycol acetate
203-839-2
111-15-9
Flam. Liq. 3; Repr. 1B; Acute Tox. 4
2-ethyl-2,3-dihydro-2-methyl-1H-perimidine
424-380-6
43057-68-7
Acute Tox. 4; STOT RE 2
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate
239-701-3
15625-89-5
Carc. 2; Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1
2-ethyl-N-methyl-N-(3-methylphenyl)butanamide
PARADISAMIDE
446-190-2
406488-30-0
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
2-ethylbutan-1-ol
202-621-4
97-95-0
Acute Tox. 4
2-ethylhexane-1,3-diol; octylene glycol; ethoexadiol
202-377-9
94-96-2
Eye Dam. 1
2-ethylhexanoato-O)(neodecanoato-O)nickel
285-698-7
85135-77-9
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
2-ethylhexanoic acid and its salts, with the exception of those specified elsewhere in this Annex
show/hide
Metal salts of 2-ethylhexanoic acid EC / List no: - | CAS no: -
2-ethylhexanoic acid EC / List no: 205-743-6 | CAS no: 149-57-5
-
-
Repr. 1B
2-ethylhexanoic acid, nickel salt
231-480-1
7580-31-6
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate
260-829-0
57583-35-4
Repr. 2; Acute Tox. 4; STOT RE 1; Skin Sens. 1A
2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate; [DOTE]
239-622-4
15571-58-1
Repr. 1B; STOT RE 1
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-methyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate
260-828-5
57583-34-3
Repr. 2
2-ethylhexyl acrylate
203-080-7
103-11-7
STOT SE 3; Skin Irrit. 2; Skin Sens. 1
2-ethylhexyl-2-ethylhexanoate
231-057-1
7425-14-1
Repr. 2
2-ethylhexyl[[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]thio]acetate
279-452-8
80387-97-9
Repr. 1B; Skin Sens. 1
2-ethylphenylhydrazine hydrochloride
2-EPH
421-460-2
19398-06-2
Carc. 2; STOT RE 1; Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
2-fluoro-4-hydroxybenzonitrile
2-FLUOR-4-HYDROXYBENZONITRIL
422-810-7
82380-18-5
Acute Tox. 4; Eye Dam. 1
2-fluoro-5-trifluoromethylpyridine
G.1417
400-290-2
69045-82-5
Flam. Liq. 3; Skin Sens. 1
2-fluoro-6-trifluoromethylpyridine
428-100-3
94239-04-0
Flam. Liq. 3; Acute Tox. 4
2-fluoroacetamide
211-363-1
640-19-7
Acute Tox. 2; Acute Tox. 3
2-furaldehyde
202-627-7
98-01-1
Carc. 2; Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
2-hexyloxyethanol; ethylene glycol monohexyl ether; n-hexylglycol
203-951-1
112-25-4
Acute Tox. 4; Skin Corr. 1B
2-hydroxy-1-(4-(4-(2-hydroxy-2-methylpropionyl)benzyl)phenyl)-2-methylpropan-1-one
444-860-9
474510-57-1
STOT RE 2
2-hydroxy-1-methylethylacrylate
220-852-9
2918-23-2
Acute Tox. 3; Skin Corr. 1B; Skin Sens. 1
2-hydroxy-2-methylpropionitrile; 2-cyanopropan-2-ol; acetone cyanohydrin
200-909-4
75-86-5
Acute Tox. 2; Acute Tox. 1
2-hydroxy-3-(2-ethyl-4-methylimidazoyl)propyl neodecanoate
EPIKURE DX 6906
417-350-9
776326-15-9
Skin Irrit. 2; Eye Dam. 1
2-hydroxy-3-[(2-hydroxyethyl)-[2-(1-oxotetradecyl)amino]ethyl]amino]-N,N,N-trimethyl-1-propanammonium chloride
AMINO CATION S-36
414-670-0
141890-30-4
Acute Tox. 4; Eye Dam. 1
2-hydroxyethyl acrylate
212-454-9
818-61-1
Acute Tox. 3; Skin Corr. 1B; Skin Sens. 1
2-hydroxyethyl methacrylate
212-782-2
868-77-9
Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
2-hydroxyethylammonium perbromide
LIQUIBROM 2038
407-440-6
127395-77-1
Ox. Sol. 2; Acute Tox. 4; Skin Corr. 1A; Skin Sens. 1
2-hydroxymethyl-9-methyl-6-(1-methylethyl)-1,4-dioxaspiro[4.5]decane
FRESCOLAT MGA
408-200-3
63187-91-7
Skin Irrit. 2; Eye Dam. 1
2-hydroxypropyl methacrylate
213-090-3
923-26-2
Eye Irrit. 2; Skin Sens. 1
2-hydroxypropylacrylate
213-663-8
999-61-1
Acute Tox. 3; Skin Corr. 1B; Skin Sens. 1
2-isobutyl-2-isopropyl-1,3-dimethoxypropane
430-800-9
129228-21-3
Skin Irrit. 2
2-isopropoxyethanol; ethylene glycol monoisopropyl ether
203-685-6
109-59-1
Acute Tox. 4; Eye Irrit. 2
2-isopropyl-2-(1-methylbutyl)-1,3-dimethoxypropane
406-970-5
129228-11-1
Skin Irrit. 2
2-isopropyl-4-(N-methyl)aminomethylthiazole
A-87463.0
414-800-6
154212-60-9
Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
2-isopropyl-5-methylcyclohexyloxycarbonyloxy-2-hydroxypropane
FRESCOLAT MPC
417-420-9
156324-82-2
Eye Irrit. 2
2-methoxy-1-methylethyl acetate
203-603-9
108-65-6
Flam. Liq. 3
2-methoxy-2-methylbutane; tert-amyl methyl ether
213-611-4
994-05-8
Flam. Liq. 2; Acute Tox. 4; STOT SE 3
2-methoxyaniline; o-anisidine
201-963-1
90-04-0
Carc. 1B; Muta. 2; Acute Tox. 3
2-methoxyethanol; ethylene glycol monomethyl ether
203-713-7
109-86-4
Flam. Liq. 3; Repr. 1B; Acute Tox. 4
2-methoxyethyl acetate; methylglycol acetate
203-772-9
110-49-6
Repr. 1B; Acute Tox. 4
2-methoxyethyl acrylate
221-499-3
3121-61-7
Flam. Liq. 3; Muta. 2; Repr. 1B; Acute Tox. 3; Acute Tox. 4; Skin Corr. 1C; Eye Dam. 1; Skin Sens. 1
2-methoxyethylmercury chloride
204-659-7
123-88-6
Acute Tox. 3; STOT RE 1; Skin Corr. 1B
2-methoxypropanol
216-455-5
1589-47-5
Flam. Liq. 3; Repr. 1B; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
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