EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

Last updated 25 April 2024. Database contains 4691 unique substances/entries.

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Showing 501 - 600 of 4,691 results.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)
2,4-dinitroaniline	202-553-5	97-02-9	Acute Tox. 2; Acute Tox. 1; STOT RE 2
2,4-dinitrophenol	200-087-7	51-28-5	Acute Tox. 3; Acute Tox. 2; STOT RE 1
2,4-dinitrotoluene	204-450-0	121-14-2	Carc. 1B; Muta. 2; Repr. 2; Acute Tox. 3; STOT RE 2
2,4-xylenol	203-321-6	105-67-9	Acute Tox. 3; Skin Corr. 1B
2,5,7,7-tetramethyloctanal LYRISAL	405-690-0	114119-97-0	Skin Irrit. 2; Skin Sens. 1
2,5-bis-isocyanatomethyl-bicyclo[2.2.1]heptane MR-8A; MR-N2; NBDI	411-280-2	161973-12-2	Acute Tox. 2; Acute Tox. 4; Skin Corr. 1B; Resp. Sens. 1; Skin Sens. 1
2,5-dibutoxy-4-(morpholin-4-yl)benzenediazonium 4-methylbenzenesulfonate DIAZO W 6623-TS	413-290-2	93672-52-7	Self-react. C; Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
2,5-dihydroxy-5-methyl-3-(morpholin-4-yl)-2-cyclopenten-1-one	430-170-5	114625-74-0	Acute Tox. 4
2,5-dimercaptomethyl-1,4-dithiane HR-11	419-770-8	136122-15-1	Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
2,5-dimethylhexane	209-745-8	592-13-2	Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
2,5-dinitrophenol	206-348-1	329-71-5	Acute Tox. 3; STOT RE 2
2,5-dinitrotoluene	210-581-4	619-15-8	Carc. 1B; Muta. 2; Repr. 2; Acute Tox. 3; STOT RE 2
2,5-dioxopyrrolidin-1-yl N-{[methyl[[2-(1-methylethyl)-4-thiazoly]methyl]amino]carbonyl}-L-Valinate	424-660-8	-	STOT RE 2; Eye Dam. 1; Skin Sens. 1
2,5-xylenol	202-461-5	95-87-4	Acute Tox. 3; Skin Corr. 1B
2,6,6,7,8,8-hexamethyldecahydro-2H-indeno[4,5-b]furan	440-030-5	338735-71-0	Skin Irrit. 2; Eye Dam. 1
2,6-bis(1,1-dimethylethyl)-4-(phenylenemethylene)cyclohexa-2,5-dien-1-one	429-460-4	7078-98-0	Skin Sens. 1
2,6-bis(2,3,4-trihydroxybenzyl)-p-cresol ester with 6-diazo-5,6-dihydro-5-oxo-1-naphthalenesulfonate	444-250-2	144111-81-9	Self-react. C
2,6-bis-(2-(4-(4-amino-phenylamino)-phenylazo)-1,3-dimethyl-3H-imidazolium)-4-dimethylamino-1,3,5-triazine, dichloride VIOLETT MIP 3250	424-120-1	174514-06-8	Eye Dam. 1
2,6-diamino-3,5-diethyltoluene; 4,6-diethyl-2-methyl-1,3-benzenediamine	218-255-3	2095-01-4	Acute Tox. 4; STOT RE 2; Eye Irrit. 2
2,6-diamino-3-((pyridine-3-yl)azo)pyridine AZOGELB	421-430-9	28365-08-4	Acute Tox. 4; STOT RE 2
2,6-dichloro-1-fluoropyridiniumtetrafluoroborate FPB 800	427-400-1	140623-89-8	Skin Corr. 1B; Acute Tox. 4; Skin Sens. 1
2,6-dichloro-4-nitroanisole T 1049	403-350-6	17742-69-7	Acute Tox. 3
2,6-dichloro-4-trifluoromethylaniline DICHLORO-2,6 P.T.F.M.A.	416-430-0	24279-39-8	Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
2,6-diethylaniline	209-445-7	579-66-8	Acute Tox. 4
2,6-dimethylheptan-4-one; di-isobutyl ketone	203-620-1	108-83-8	Flam. Liq. 3; STOT SE 3
2,6-dinitrophenol	209-357-9	573-56-8	Acute Tox. 3; STOT RE 2
2,6-dinitrotoluene	210-106-0	606-20-2	Carc. 1B; Muta. 2; Repr. 2; Acute Tox. 3; STOT RE 2
2,6-xylenol	209-400-1	576-26-1	Acute Tox. 3; Skin Corr. 1B
2,6-xylidine; 2,6-dimethylaniline	201-758-7	87-62-7	Carc. 2; Acute Tox. 4; STOT SE 3; Skin Irrit. 2
2,7,11-trimethyl-13-(2,6,6-trimethylcyclohex-1-en-1-yl)tridecahexaen-2,4,6,8,10,12-al C25-ALDEHYD	415-770-7	1638-05-7	STOT RE 2; Skin Sens. 1
2,7-naphthalenedisulfonic acid, nickel(II) salt	-	72319-19-8	Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
2,9-bis(3-(diethylamino)propylsulfamoyl)quino(2,3-b)acridine-7,14-dione PIGMENT ADDITIV AC; PIGMENTADDITIV AC	404-230-6	164578-11-4	Skin Sens. 1
2-((4-(ethyl-(2-hydroxyethyl)amino)-2-methylphenyl)azo)-6-methoxy-3-methyl-benzothiazolium methylsulfate FAT 40'398; FAT 40'398/E	411-100-2	136213-73-5	STOT RE 2; Skin Sens. 1
2-((4-amino-2-nitrophenyl)amino)benzoic acid RO 1082	411-260-3	117907-43-4	Eye Dam. 1; Skin Sens. 1
2-((4-methyl-2-nitrophenyl)amino)ethanol METHYLGELB	408-090-7	100418-33-5	Acute Tox. 4; Skin Sens. 1
2-(1-methylpropyl)-4-tert-butylphenol 2S4TBP	421-740-4	51390-14-8	Skin Corr. 1B
2-(10-oxo-10H-9-oxa-10-phosphaphenanthren-10-ylmethyl)succinic acid	426-480-5	63562-33-4	Skin Sens. 1
2-(2,4-dichlorophenyl)-1-(1H—1,2,4-triazol-1-yl)pent-4-en-2-ol TAA	407-850-5	89544-40-1	Acute Tox. 4; Eye Dam. 1
2-(2,4-dichlorophenyl)-2-(2-propenyl)oxirane EPO	411-210-0	89544-48-9	Skin Irrit. 2; Skin Sens. 1
2-(2-(2-hydroxyethoxy)ethyl)-2-aza-bicyclo[2.2.1]heptane THANCAT AN 20	407-360-1	116230-20-7	Acute Tox. 4; STOT RE 2; Skin Irrit. 2; Eye Dam. 1
2-(2-amino-1,3-thiazol-4-yl)-(Z)-2-methoxyiminoacetyl chloride hydrochloride 31 AC-HCL	410-620-7	119154-86-8	Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
2-(2-aminoethylamino)ethanol; (AEEA)	203-867-5	111-41-1	Repr. 1B; Skin Corr. 1B; Skin Sens. 1
2-(2-bromoethoxy)anisole GUAIACOL-O-ETHYLBROMIDE	402-010-4	4463-59-6	Acute Tox. 4
2-(2-butoxyethoxy)ethanol; diethylene glycol monobutyl ether	203-961-6	112-34-5	Eye Irrit. 2
2-(2-butoxyethoxy)ethyl thiocyanate	203-985-7	112-56-1	Flam. Liq. 3; Acute Tox. 3
2-(2-hexyloxyethoxy)ethanol; DEGHE; diethylene glycol monohexyl ether; 3,6-dioxa-1-dodecanol; hexyl carbitol; 3,6-dioxadodecan-1-ol	203-988-3	112-59-4	Acute Tox. 4; Eye Dam. 1
2-(2-hydroxy-3,5-dinitroanilino)ethanol PIKRAMINROT	412-520-9	99610-72-7	Flam. Sol. 2; Repr. 2; Acute Tox. 4
2-(2-iodoethyl)-1,3-propanediol diacetate BRL 47539	411-780-0	127047-77-2	Acute Tox. 4
2-(2-methoxyethoxy)ethanol; diethylene glycol monomethyl ether	203-906-6	111-77-3	Repr. 1B
2-(3,4-dichlorophenyl)-4-methyl-1,2,4-oxadiazolidinedione; methazole	243-761-6	20354-26-1	Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
2-(3,4-epoxycyclohexyl)ethyltriethoxy silane	425-050-4	10217-34-2	Skin Sens. 1
2-(3-(prop-1-en-2-yl)phenyl)prop-2-yl isocyanate M-TMI	402-440-2	2094-99-7	Acute Tox. 2; Skin Corr. 1B; STOT RE 2; Resp. Sens. 1; Skin Sens. 1
2-(3-bromophenoxy)tetrahydro-2H-pyran CP-328,914	429-030-6	57999-49-2	Skin Sens. 1
2-(3-chloropropyl)-2,5,5-trimethyl-1,3-dioxane 5-CHLOR-2-PENTANON-NEOPENTYLKETAL; 5-CHLORO-2-PENTANONE-NEOPENTYLKETAL; CHLORKETAL	417-650-1	88128-57-8	STOT RE 2
2-(3-iodoprop-2-yn-1-yloxy)ethyl phenylcarbamate SIS 46 305	408-010-0	88558-41-2	Acute Tox. 4; Eye Dam. 1
2-(4-(3-(4-chlorophenyl)-2-pyra zolin-1-yl)phenylsulfonyl)ethyldimethylammonium formate HOSTALUX VP 3481-1 HOSTALUX N2R	402-120-2	133514-97-3	Skin Corr. 1B; STOT RE 2; Skin Sens. 1
2-(4-(3-(4-chlorophenyl)-4,5- dihydropyrazolyl)phenylsulphonyl) ethyldimethylammonium hydrogen phosphonate AZURANT PYRAZOLINE MR 5401; PYRAZOLINE BRIGHTENER MR 5401; UVITEX 4457	402-490-5	106359-93-7	Eye Irrit. 2
2-(4-(4-(butyl-(1-methylhexyl)amino)phenyl)-3-cyano-5-oxo-1,5-dihydropyrrol-2-ylidene)propandinitrile	429-180-2	157362-53-3	Skin Sens. 1
2-(4-(4-cyano-3-methylisothiazol-5-ylazo)-N-ethyl-3-methylanilino)ethyl acetate TTP MAGENTA 3	405-480-9	110260-50-9	Acute Tox. 4; STOT RE 2; Skin Irrit. 2
2-(4-(5,6(or 6,7)-dichloro-1,3-benzothiazol-2-ylazo)-N-methyl-m-toluidino)ethyl acetate BRILLANT RED 1047729; BRILLIANT RED 1047729; ROUGE BRILLANT 1047729	405-440-0	149172-69-0	Skin Sens. 1
2-(4-(diethylaminopropylcarbamoyl)phenylazo)-3-oxo-N-(2,3-dihydro-2-oxobenzimidazol-5-yl)butyramide PIGMENT ADDITIV C	404-910-2	164578-14-7	Skin Sens. 1
2-(4-aminophenyl)-6-tert-butyl-1H-pyrazolo[1,5-b][1,2,4]triazole FC-102B; M-3218	415-910-7	152828-25-6	Skin Sens. 1
2-(4-chloro-2-methylphenoxy)propionic acid;mecoprop (ISO); 2-(4-chloro-o-tolyloxy)propionic acid; (RS)-2-(4-chloro-o-tolyloxy)propionic acid	202-264-4	7085-19-0;93-65-2	Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
2-(4-chloro-2-methylphenoxy)propionic acid;mecoprop (ISO); 2-(4-chloro-o-tolyloxy)propionic acid; (RS)-2-(4-chloro-o-tolyloxy)propionic acid	202-264-4	7085-19-0;93-65-2	Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
2-(4-methyl-2-phenyl-1-piperazinyl)benzenemethanol monohydrochloride	420-200-5	1379676-70-6	Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
2-(4-methyl-3-pentenyl)anthraquinone	428-320-1	71308-16-2	Acute Tox. 4; Skin Sens. 1
2-(4-tert-butylbenzyl)propionaldehyde	201-289-8	80-54-6	Repr. 1B
2-(4-tert-butylphenyl)ethanol TBPE	410-020-5	5406-86-0	Repr. 2; STOT RE 2; Eye Dam. 1
2-(5,5-dimethyl-2,4-dioxooxazolidin-3-yl)-4,4-dimethyl-3-oxo-N-(2-methoxy-5-octadecanoylaminophenyl)pentanoic acid amide	443-980-9	221215-20-9	Skin Sens. 1
2-(7-ethyl-1H-indol-3-yl)ethanol 7-ETHYLTRYPTOPHOL	431-020-1	41340-36-7	Acute Tox. 4; STOT RE 2
2-(decylthio)ethylammonium chloride XU 40304.03L ANTIMICROBIAL	405-640-8	36362-09-1	STOT RE 2; Skin Irrit. 2; Eye Dam. 1
2-(diphosphonomethyl)succinic acid KEINE	403-070-4	51395-42-7	Skin Corr. 1B; Skin Sens. 1
2-(formylamino)-3-thiophenecarboxylic acid; 2-formamido-3-thiophenecarboxylic acid	431-930-9	43028-69-9	Acute Tox. 4; Skin Sens. 1
2-(isocyanatosulfonylmethyl)benzoic acid methyl ester; (alt.):methyl 2-(isocyanatosulfonylmethyl)benzoate MCPSI	410-900-9	83056-32-0	Flam. Liq. 3; Muta. 2; Acute Tox. 4; STOT RE 2; Eye Dam. 1; Resp. Sens. 1
2-(morpholinothio)benzothiazole	203-052-4	102-77-2	Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
2-(N-benzyl-N-methylamino)ethyl 3-amino-2-butenoate EM	405-350-1	54527-73-0	Skin Sens. 1
2-(O-aminooxy)ethylamine dihydrochloride AMINOETHER	412-310-7	37866-45-8	Skin Sens. 1
2-(octylthio)ethanol; 2-hydroxyethyl octyl sulphide	222-598-4	3547-33-9	Eye Dam. 1
2-(para-chlorophenyl)glycineamide	420-830-0	102333-75-5	Eye Dam. 1; Skin Sens. 1
2-(propyloxy)ethanol; EGPE	220-548-6	2807-30-9	Acute Tox. 4; Eye Irrit. 2
2-(trimethylammonium)ethoxycarboxybenzene-4-sulfonate CSPC	411-010-3	117205-23-9	Skin Sens. 1
2-[(2-[2-(dimethylamino)ethoxy]ethyl)methylamino]ethanol JEFFCAT ZF-10; TEXACAT ZF-10	406-080-7	83016-70-0	Acute Tox. 4; Skin Corr. 1B
2-[(4-chloro-2-nitrophenyl)amino]ethanol CHLORGELB; HC YELLOW 12	413-280-8	59320-13-7	Acute Tox. 4
2-[2-(2-butoxyethoxy)ethoxy]ethanol; TEGBE; triethylene glycol monobutylether; butoxytriethylene glycol	205-592-6	143-22-6	Eye Dam. 1
2-[2-hydroxy-3-(2-chlorophenyl)carbamoyl-1-naphthylazo]-7-[2-hydroxy-3-(3-methylphenyl)carbamoyl-1-naphthylazo]fluoren-9-one P-964	420-580-2	151798-26-4	Repr. 1B
2-[3-(methylamino)propyl]-1H-benzimidazole	425-760-4	64137-52-6	Eye Dam. 1
2-[[4[[4,6-bis[[3-(diethylamino)propyl]amino]-1,3,5-triazine-2-yl]amino]phenyl]azo]-N-(2,3-dihydro-2-oxo-1H-benzimidazol-5-yl)-3-oxobutanamide KAYACEL YELLOW CG; NO.466 BZN	407-680-1	98809-11-1	Eye Dam. 1; Skin Sens. 1
2-[N-ethyl-4-[(5-nitrothiazol-2-yl)azo]-m-toluidino]ethyl acetate; C.I. Disperse Blue 124	239-203-6	15141-18-1	Skin Sens. 1A
2-acetoxymethylene-4-acetylphenylacetate	425-160-2	24085-06-1	Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1
2-alkoyloxyethyl hydrogen maleate, where alkoyl represents (by weight 70 to 85 % unsaturated octadecoyl, 0.5 to 10 % saturated octadecoyl, and 2 to 18 % saturated hexadecoyl ATRAC 869	417-960-5	-	Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
2-amino-2-methylpropanol	204-709-8	124-68-5	Eye Irrit. 2; Skin Irrit. 2
2-amino-4,6-dinitrophenol; picramic acid;2-amino-4,6-dinitrophenol; picramic acid [≥ 20 % water]	202-544-6	96-91-3	Expl. 1.1; Acute Tox. 4
2-amino-4,6-dinitrophenol; picramic acid;2-amino-4,6-dinitrophenol; picramic acid [≥ 20 % water]	202-544-6	96-91-3	Acute Tox. 4
2-amino-4-(trifluoromethyl)benzenethiol hydrochloride	429-560-8	4274-38-8	Skin Corr. 1B; Acute Tox. 4; STOT RE 2; Skin Sens. 1
2-amino-4-bromo-5-chlorobenzoic acid ACIDE CÉBRANILIQUE	424-700-4	150812-32-1	Eye Dam. 1
2-amino-4-chloro-6-methoxypyrimidine DPX N6186; N 6186	410-050-9	5734-64-5	Acute Tox. 4
2-amino-4-dimethylamino-6-trifluoroethoxy-1,3,5-triazine	415-500-8	145963-84-4	Acute Tox. 4; STOT RE 2
2-amino-5-methylthiazole 2-AMINO-5-METHYLTHIAZOL	423-800-5	7305-71-7	Acute Tox. 4; STOT RE 2
2-amino-6-ethoxy-4-methylamino-1,3,5-triazine DPX-D-7556	403-580-7	62096-63-3	Acute Tox. 4
2-aminoethanol; ethanolamine	205-483-3	141-43-5	Acute Tox. 4; Skin Corr. 1B

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EU-SAFETY_HEALTH_WORK-PREAMBLE

EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

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Last updated 25 April 2024. Database contains 4691 unique substances/entries.

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