EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

Last updated 25 April 2024. Database contains 4691 unique substances/entries.

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Showing 101 - 200 of 4,691 results.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)
(R)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone	226-908-9	5543-58-8	Repr. 1A; Acute Tox. 1; Acute Tox. 2; STOT RE 1
(R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole UK-111,975	422-390-5	143322-57-0	Repr. 2; STOT RE 1; Acute Tox. 4; Skin Sens. 1
(R)-butan-2-ol	238-967-8	14898-79-4	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
(R)-p-mentha-1,8-diene; d-limonene	227-813-5	5989-27-5	Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1B; Asp. Tox. 1
(R)-α-phenylethylammonium(-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate PHENETHYLAMMONIUM SALT OF FOSFOMYCIN	418-570-8	25383-07-7	Repr. 2
(R, S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate	445-750-3	839705-03-2	Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
(R, S)-2-amino-3,3-dimethylbutane amide	447-860-7	144177-62-8	Repr. 2; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
(R, S)-2-azabicyclo[2.2.1]hept-5-en-3-one	421-830-3	49805-30-3	Acute Tox. 4; Skin Sens. 1
(R, S)-2-butyloctanedioic acid 2-BUTYLOCTANEDIOIC ACID	431-210-4	50905-10-7	Eye Dam. 1
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile	430-780-1	103146-25-4	Acute Tox. 4; Skin Sens. 1
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)3-(hydroxymethyl)benzonitrile hemisulfate	430-790-6	-	Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
(RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy} ethyl methyl carbonate; tolpyralate	701-225-3	1101132-67-5	Carc. 2; Repr. 2; STOT RE 2
(RS)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole; medetomidine	811-718-6	86347-14-0	Acute Tox. 2; STOT SE 3; STOT SE 1; STOT RE 1
(S)-(-)-2-acetoxypropionylchloride; (1S)-2-chloro-1-methyl-2-oxoethyl acetate	420-610-4	36394-75-9	Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
(S)-2,2-diphenyl-2-(3-pyrrolidinyl)acetonitrile hydrobromide UK-88,861-04	421-810-4	194602-27-2	Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
(S)-2,3-dihydro-1H-indole-2-carboxylic acid [S]-2-INDOLINE CARBOXYLIC ACID	410-860-2	79815-20-6	Repr. 2; STOT RE 2; Skin Sens. 1
(S)-2-chloropropionic acid L-2-CHLOROPROPIONIC ACID; L-2-CHLORPROPIONSÄURE	411-150-5	29617-66-1	Acute Tox. 4; Skin Corr. 1A
(S)-3-hydroxy-γ-butyrolactone	434-990-4	7331-52-4	Skin Sens. 1
(S)-3-methyl-2-(2-oxotetrahydropyrimidine-1-yl)butyric acid	430-900-2	192725-50-1	Eye Dam. 1
(S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile	430-770-7	128173-52-4	Acute Tox. 4; Skin Sens. 1
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone	226-907-3	5543-57-7	Repr. 1A; Acute Tox. 1; Acute Tox. 2; STOT RE 1
(S)-azetidine-2-carboxylic acid; 4-cyanobenzylamide hydrochloride	433-010-2	2135910-74-4	Acute Tox. 4; Skin Sens. 1
(S)-butan-2-ol	224-168-1	4221-99-2	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
(S)-methyl-2-chloropropionate L (-) CHLOROPROPIONATE DE METHYLE; S (-) CHLOROPROPIONATE DE METHYLE	412-470-8	73246-45-4	Flam. Liq. 3; STOT RE 2; Eye Irrit. 2
(S)-N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide CZ-AMIDE; PTH-TETRAHYDROAMIDE; TETRAHYDROAMIDE (THA)	414-600-9	149182-72-9	Acute Tox. 4
(S)-p-mentha-1,8-diene; l-limonene	227-815-6	5989-54-8	Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1
(S)-α-(acetylthio)benzenepropanoic acid BMS 187266-02; S-TIPAC	430-300-0	76932-17-7	Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
(S)-α-hydroxy-3-phenoxy-benzeneacetonitrile	441-070-6	61826-76-4	Acute Tox. 3; Eye Dam. 1; Skin Sens. 1
(S,S)-trans-4-(acetylamino)-5,6-dihydro-6-methyl-7,7-dioxo-4H-thieno[2,3-b]thiopyran-2-sulfonamide TRUSOPT INTERMEDIATE, L-686,771	415-030-3	120298-38-6	Skin Sens. 1
(tetrasodium 1-(4-(3-acetamido-4-(4'-nitro-2,2'-disulfonatostilben-4-ylazo)anilino)-6-(2,5-disulfonatoanilino)-1,3,5-triazin-2-yl)-3-carboxypyridinium) hydroxide BENACTIVE GOLDEN YELLOW CN-GL; C.I. REACTIVE YELLOW 178; KAYACELON REACT GOLDEN YELLOW CN-GL; SOMAZIN GOLDEN YELLOW CN-GL	404-250-5	115099-55-3	Skin Sens. 1
(tris(chloromethyl)phthalocyaninato)copper(II), reaction products with N-methylpiperazine and methoxyacetic acid CARTASOL TUERKIS K-ZBL KONC.; CARTASOL TURQUOISE K-JD 2336; CARTASOL TURQUOISE K-JD 2336 CONC.; CARTASOL TURQUOISE K-ZBL CONC.; CARTASOL TÜRKIS K-ZBL FLÜSSIG; CARTASOL TÜRKIS K-ZBL KONZ.; TURQUOISE CARTASOL K-JD 2336 CONC.	401-260-1	118800-27-4	Eye Irrit. 2
(trisodium (2-((3-(6-(2-chloro-5-sulfonato)anilino)-4-(3-carboxypyridinio)-1,3,5-triazin-2-ylamino)-2-oxido-5-sulfonatophenylazo)phenylmethylazo)-4-sulfonatobenzoato)copper(3-)) hydroxide C.I. REAKTIV-BLAU 216; KAYACELON REACT BLUE CN-BL; KAYACELON REAKT-BLAU CN-BL; UBCNBL	404-670-9	89797-01-3	Skin Sens. 1
(Z)-(2,4-difluorophenyl)piperidin-4-ylmethanone oxime monohydrochloride	424-740-2	138271-16-6	Acute Tox. 4; Eye Dam. 1
(Z)-1,3-dichloropropene	233-195-8	10061-01-5	Flam. Liq. 3; Acute Tox. 3; Acute Tox. 4; Asp. Tox. 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
(Z)-1-benzo[b]thien-2-ylethanone oxime hydrochloride A-83851	410-780-8	1379676-72-8	Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1
(Z)-13-docosenyl-N,N-bis(2-hydroxyethyl)-N-methyl-ammonium-chloride CLEARFRAC J508B	426-210-6	120086-58-0	Skin Corr. 1B
(Z)-2-(2-t-butoxycarbonylamino-4-thiazolyl)pent-2-enoic acid	430-100-3	86978-24-7	Acute Tox. 4
(Z)-2-methoxy-4-(prop-1-enyl)phenol	227-633-7	5912-86-7	Skin Sens. 1A
(Z)-2-methoxymino-2-[2-(tritylamino)thiazol-4-yl]acetic acid	431-520-1	64485-90-1	Flam. Sol. 1; Carc. 2
(Z)-but-2-ene	209-673-7	590-18-1	Flam. Gas 1; Press. Gas
(Z)-octadec-9-enylamine	204-015-5	112-90-3	Acute Tox. 4; Asp. Tox. 1; STOT SE 3; STOT RE 2; Skin Corr. 1B
(±) trans—3,3-dimethyl-5-(2,2,3-trimethyl-cyclopent-3-en-1-yl)-pent-4-en-2-ol POLYSANTOL	411-580-3	107898-54-4	Skin Irrit. 2
(±)-1-[2-(allyloxy)ethyl-2-(2,4- dichlorophenyl)]-1H-imid azolium hydrogen sulphate	281-291-3	83918-57-4	Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
(±)-1-[2-(allyloxy)ethyl-2-(2,4- dichlorophenyl)]-1H-imid azolium hydrogen sulphate	281-291-3	83918-57-4	Acute Tox. 4; Skin Sens. 1
(±)-1-methyl-4-(1-methylvinyl)cyclohexene;dipentene; limonene	205-341-0	138-86-3;7705-14-8	Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1
(±)-1-methyl-4-(1-methylvinyl)cyclohexene;dipentene; limonene	205-341-0	138-86-3;7705-14-8	Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1
(±)-4-(3-chlorophenyl)-6-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl]-1-methyl-2(1H)-quinolin	430-730-9	-	Eye Dam. 1
(±)-4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]-1-hydroxyethyl]phenol hydrochloride PAYLEAN; RACTOPAMINE HYDROCHLORIDE	415-170-5	90274-24-1	Acute Tox. 4; Skin Sens. 1
(±)-[(R,R) and (R,S)]-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran T001446	419-600-2	99199-90-3	Skin Sens. 1
(±)-butan-2-ol;butan-2-ol	201-158-5	15892-23-6;78-92-2	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
(±)-butan-2-ol;butan-2-ol	201-158-5	15892-23-6;78-92-2	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
(±)-trans-4-(4-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine BRL 44742	415-550-0	109887-53-8	Acute Tox. 4; Eye Dam. 1
(±)-α-[(2-acetyl-5-methylphenyl)-amino]-2,6-dichlorobenzene-aceto-nitrile T001769	419-290-9	780757-44-0	Skin Sens. 1
(η-cumene)-(η-cyclopentadienyl)iron(II) hexafluoroantimonate CG 24-020; FERROCEN-SBF6	407-840-0	100011-37-8	Acute Tox. 4; Eye Dam. 1
(η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate CG 26-751	407-880-9	117549-13-0	Acute Tox. 4
1,1',1'-nitrilotripropan-2-ol; triisopropanolamine	204-528-4	122-20-3	Eye Irrit. 2
1,1'-(1,3-phenylenedioxy)bis(3-(2-(prop-2-enyl)phenoxy)propan-2-ol) COMPIMIDE™ 121	405-840-5	110866-35-8	Skin Sens. 1
1,1'-dioxybiscyclohexan-1-ol;1,1'-dioxybiscyclohexan-1-ol [≤ 91 % solution]	219-306-2	2407-94-5	Org. Perox. A; Skin Corr. 1B; Acute Tox. 4
1,1'-dioxybiscyclohexan-1-ol;1,1'-dioxybiscyclohexan-1-ol [≤ 91 % solution]	219-306-2	2407-94-5	Org. Perox. C; Acute Tox. 4; Skin Corr. 1B
1,1'-iminodipropan-2-ol; di-isopropanolamine	203-820-9	110-97-4	Eye Irrit. 2
1,1,1,3,3-pentafluorobutane	430-250-1	406-58-6	Flam. Liq. 2
1,1,1-trichloroethane; methyl chloroform	200-756-3	71-55-6	Acute Tox. 4
1,1,2,2-tetrabromoethane	201-191-5	79-27-6	Acute Tox. 2; Eye Irrit. 2
1,1,2,2-tetrachloroethane	201-197-8	79-34-5	Acute Tox. 2; Acute Tox. 1
1,1,2-trichloroethane	201-166-9	79-00-5	Carc. 2; Acute Tox. 4
1,1,3,3-tetrabutyl-1,3-ditinoxydicaprylate D 28-283	419-430-9	56533-00-7	Acute Tox. 4; STOT RE 2; Skin Corr. 1B
1,1,3,3-tetramethylbutylperoxypivalate	424-980-8	22288-41-1	Flam. Liq. 2; Org. Perox. D; Skin Irrit. 2; Skin Sens. 1
1,1-dichloro-1-nitroethane	209-854-0	594-72-9	Acute Tox. 3
1,1-dichloroethane	200-863-5	75-34-3	Flam. Liq. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
1,1-dichloroethylene; vinylidene chloride	200-864-0	75-35-4	Flam. Liq. 1; Carc. 2; Acute Tox. 4
1,1-dichloropropene	209-253-3	563-58-6	Flam. Liq. 2; Acute Tox. 3
1,1-diethoxyethane; acetal	203-310-6	105-57-7	Flam. Liq. 2; Eye Irrit. 2; Skin Irrit. 2
1,1-diisopropoxycyclohexane	413-740-8	1132-95-2	Skin Corr. 1B
1,1-dimethoxyethane; dimethyl acetal	208-589-8	534-15-6	Flam. Liq. 2
1,1-dimethyl-3-phenyluronium trichloroacetate; fenuron-TCA	-	4482-55-7	Skin Irrit. 2
1,1-dimethylethyl 4'-(bromomethyl)biphenyl-2-carboxylate	442-850-9	114772-40-6	Skin Sens. 1
1,1-dimethylpropyl 3,5,5-trimethylperoxyhexanoate LUPEROX 570	431-610-9	68860-54-8	Org. Perox. D; Skin Sens. 1
1,10-phenanthroline	200-629-2	66-71-7	Acute Tox. 3
1,2,3,4,5,6-hexachlorcyclohexanes with the exception of those specified elsewhere in this Annex	210-168-9	608-73-1	Carc. 2; Acute Tox. 3; Acute Tox. 4
1,2,3,4-tetrahydro-1-naphthyl hydroperoxide	212-230-0	771-29-9	Org. Perox. D; Acute Tox. 4; Skin Corr. 1B
1,2,3,4-tetrahydro-6-nitro-quinoxaline RO 1173	414-270-6	41959-35-7	Acute Tox. 4
1,2,3,4-tetrahydronaphthalene	204-340-2	119-64-2	Eye Irrit. 2; Skin Irrit. 2
1,2,3,4-tetranitrocarbazole	-	6202-15-9	Expl. 1.1; Acute Tox. 4
1,2,3,6-tetrahydro-3,6-methanophthalic anhydride	212-557-9	826-62-0	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
1,2,3,6-tetrahydro-3-methylphthalic anhydride	226-247-6	5333-84-6	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
1,2,3,6-tetrahydro-4-methylphthalic anhydride	222-323-8	3425-89-6	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
1,2,3,6-tetrahydromethylphthalic anhydride	247-830-1	26590-20-5	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
1,2,3,6-tetrahydrophthalic anhydride	201-605-4	85-43-8	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
1,2,3-trichloropropane	202-486-1	96-18-4	Carc. 1B; Repr. 1B; Acute Tox. 4
1,2,4-triazole	206-022-9	288-88-0	Repr. 1B; Acute Tox. 4; Eye Irrit. 2
1,2,4-trichlorobenzene	204-428-0	120-82-1	Acute Tox. 4; Skin Irrit. 2
1,2,4-trimethylbenzene	202-436-9	95-63-6	Flam. Liq. 3; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
1,2,5,6,9,10-hexabromocyclododecane	221-695-9	3194-55-6	Repr. 2; Lact.
1,2-benzenedicarboxylic acid, dihexyl ester, branched and linear	271-093-5	68515-50-4	Repr. 1B
1,2-benzenedicarboxylic acid, dipentylester, branched and linear	284-032-2	84777-06-0	Repr. 1B
1,2-benzenedicarboxylic acid; di-C6-8-branched alkylesters, C7-rich	276-158-1	71888-89-6	Repr. 1B
1,2-benzenedicarboxylic acid; di-C7-11-branched and linear alkylesters	271-084-6	68515-42-4	Repr. 1B
1,2-benzisothiazol-3(2H)-one; 1,2-benzisothiazolin-3-one	220-120-9	2634-33-5	Acute Tox. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1A
1,2-bis(2-methoxyethoxy)ethane; TEGDME; triethylene glycol dimethyl ether; triglyme	203-977-3	112-49-2	Repr. 1B
1,2-bis[4-fluoro-6-{4-sulfo-5-(2-(4-sulfonaphtalene-3-ylazo)-1-hydroxy-3,6-disulfo-8-aminonaphthalene-7-ylazo)phenylamino}-1,3,5-triazin-2ylamino]ethane; x-sodium, y-potassium salts x = 7,755 y =0,245 REACTIVE NAVY DER 7678	417-610-1	155522-09-1	Skin Sens. 1

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EU-SAFETY_HEALTH_WORK-PREAMBLE

EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

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Last updated 25 April 2024. Database contains 4691 unique substances/entries.

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