EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

Last updated 23 April 2024. Database contains 4691 unique substances/entries.

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Showing 1,001 - 1,100 of 4,691 results.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)
4-nitrobiphenyl	202-204-7	92-93-3	Carc. 1B
4-nitrophenol; p-nitrophenol	202-811-7	100-02-7	Acute Tox. 4; STOT RE 2
4-nitrosoaniline	211-535-6	659-49-4	Acute Tox. 4
4-nitrosomorpholine	627-564-6	59-89-2	Carc. 1B; Muta. 2; STOT RE 1
4-nitrosophenol	203-251-6	104-91-6	Muta. 2; Acute Tox. 4; Eye Dam. 1
4-nitrotoluene	202-808-0	99-99-0	Acute Tox. 3; STOT RE 2
4-nonylphenol, branched	284-325-5	84852-15-3	Repr. 2; Acute Tox. 4; Skin Corr. 1B
4-nonylphenol, reaction products with formaldehyde and dodecane-1-thiol POLYSTAY K; WINGSTAY K	404-160-6	164907-73-7	Skin Sens. 1
4-o-tolylazo-o-toluidine; 4-amino-2',3-dimethylazobenzene; fast garnet GBC base; AAT; o-aminoazotoluene	202-591-2	97-56-3	Carc. 1B; Skin Sens. 1
4-oxo-4-(p-tolyl)butyric acid adduct with 4-ethylmorpholine	419-240-6	171054-89-0	Eye Dam. 1
4-phenylbut-1-ene 4-PHENYL-1-BUTENE; SQ 31,175; SQ31175	405-980-7	768-56-9	Skin Irrit. 2
4-propylcyclohexanone BICH-3 STUFE 3	406-810-4	40649-36-3	Skin Irrit. 2
4-tert-butylbenzoic acid	202-696-3	98-73-7	Repr. 1B; STOT RE 1; Acute Tox. 4
4-tert-butylphenol	202-679-0	98-54-4	Repr. 2; Skin Irrit. 2; Eye Dam. 1
4-vinylcyclohexene	202-848-9	100-40-3	Carc. 2
4-{[(6-chloropyridin-3-yl)methyl](2,2-difluoroethyl)amino}furan-2(5H)-one; flupyradifurone	804-373-8	951659-40-8	Acute Tox. 4; STOT RE 2
4H-3,1-benzoxazine-2,4(1H)-dione	204-255-0	118-48-9	Eye Irrit. 2; Skin Sens. 1
5(or 6)-tert-butyl-2'-chloro-6'-ethylamino-3',7'-dimethylspiro(isobenzofuran-1(1H),9'-xanthene)-3-one R-GELB 2454	400-680-2	98181-47-6	Acute Tox. 4
5,5-dimethyl-3-oxocyclohex-1-enyl dimethylcarbamate 5,5-dimethyldihydroresorcinol dimethylcarbamate; dimetan	204-525-8	122-15-6	Acute Tox. 3
5,5-dimethyl-perhydro-pyrimidin-2-one α-(4-trifluoromethylstyryl)-α-(4-trifluoromethyl)cinnamylidenehydrazone HYDRAMETHYLNON	405-090-9	67485-29-4	STOT RE 1; Acute Tox. 4; Eye Irrit. 2
5,6,12,13-tetrachloroanthra(2,1,9-def:6,5,10-d'e'f')diisoquinoline-1,3,8,10(2H,9H)-tetrone PIGMENTROT 1017; SUBSTANCE H112287	405-100-1	115662-06-1	Repr. 2
5,6-dihydro-3H-imidazo[2,1-c]-1,2,4-dithiazole-3-thione; etem	251-684-4	33813-20-6	Acute Tox. 4
5,6-dihydroxy-2,3-dihydro-1H-indolium bromide	421-170-6	138937-28-7	Acute Tox. 4; Eye Dam. 1
5,6-dihydroxyindole IMEXINE OAY	412-130-9	3131-52-0	Acute Tox. 4; Eye Dam. 1
5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine)-3-fluoro-2-hydroxymethyltetrahydrofuran 123U83; DDFU	415-360-8	41107-56-6	Muta. 2
5-(2-amino-5-cyano-6-[2-(2-hydroxyethoxy)ethylamino]-4-methylpyridin-3-ylazo)-3-methyl-2,4-dicarbonitrilethiophene	410-530-8	107815-88-3	Skin Sens. 1
5-(2-bromophenyl)-2-tert-butyl-2H-tetrazole WAY-128170	420-820-6	153042-18-3	Flam. Liq. 3; Acute Tox. 4
5-(3,6,9-trioxa-2-undecy loxy)benzo(d)-1,3-dioxolane; sesamex	-	51-14-9	Acute Tox. 4
5-(4-[4-[4-(3,5-dicarboxy-phenyl-azo)phenylamino]-6-morpholin-4-yl-1,3,5-triazin-2-ylamino]phenylazo)isophthalic acid, mixed monosodium and diammonium salt	414-410-6	1379676-83-1	Eye Dam. 1; Skin Sens. 1
5-[[4-chloro-6-[[2-[[4-fluoro-6-[[5-hydroxy-6-[(4-methoxy-2-sulfophenyl)azo]-7-sulfo-2-naphthalenyl]amino]-1,3,5-triazin-2-yl]amino]-1-methylethyl]amino]-1,3,5-triazin-2-yl]amino]-3-[[4-(ethenylsulfonyl)phenyl]azo]-4-hydroxy-naphtalene-2,7-disulfonic acid, sodium salt ROUGE REACTIF REN 208	418-380-5	168113-78-8	Eye Dam. 1
5-acetoxy-2-(R, S)butyryloxymethyl-1,3-oxathiolane	433-530-1	143446-73-5	Acute Tox. 4; Skin Sens. 1
5-acetyl-3-amino-10,11-dihydro-5H-dibenz[b, f]azepine-hydrochloride 5-ACETYL-3-AMINO-IMINODIBENZYL.HCL	410-490-1	138451-65-7	Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1
5-amino-2,4,6-triiodo-1,3-benzenedicarbonyldichloride ATIPACL	417-220-1	37441-29-5	Skin Sens. 1
5-amino-6-methyl-1,3-dihydrobenzoimidazol-2-one	428-410-9	67014-36-2	Acute Tox. 4; Skin Sens. 1
5-bromo-8-naphtholactam FAT 92'374	413-480-5	24856-00-6	Acute Tox. 4; Skin Sens. 1
5-chloro-1,3-dihydro-2H-indol-2-one CP-13,853	412-200-9	17630-75-0	Repr. 2; Acute Tox. 4; Skin Sens. 1
5-chloro-2,3-difluoropyridine CDFP	410-090-7	89402-43-7	Flam. Liq. 3; Acute Tox. 4
5-chloro-2-(4-chlorophenoxy)phenol	429-290-0	3380-30-1	Eye Dam. 1
5-endo-hexyl-bicyclo[2.2.1]hept-2-ene	435-000-3	22094-83-3	Asp. Tox. 1; Skin Irrit. 2
5-ethoxy-5H-furan-2-one	428-330-4	2833-30-9	Skin Corr. 1B; Acute Tox. 4; STOT RE 2; Skin Sens. 1
5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one	414-470-3	95885-13-5	Acute Tox. 4
5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide; 2'-[(RS)-1,3-dimethylbutyl]-5-fluoro-1,3-dimethylpyrazole-4-carboxanilide; penflufen	619-823-7	494793-67-8	Carc. 2
5-methylheptan-3-one	208-793-7	541-85-5	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
5-methylhexan-2-one; isoamyl methyl ketone	203-737-8	110-12-3	Flam. Liq. 3; Acute Tox. 4
5-methylpyrazine-2-carboxylic acid 5-METHYLPYRAZINE-2-CARBOXYLIC ACID; ACIDO 5-METILPIRAZIN CARBOSSILICO	413-260-9	5521-55-1	Eye Dam. 1
5-nitro-o-toluidine	202-765-8	99-55-8	Carc. 2; Acute Tox. 3
5-nitro-o-toluidine hydrochloride	256-960-8	51085-52-0	Carc. 2; Acute Tox. 3
5-nitroacenaphthene	210-025-0	602-87-9	Carc. 1B
5-tert-butyl-3-isoxazolylamine hydrochloride BISOX HCL	404-840-2	164578-13-6	Acute Tox. 4; STOT RE 2; Eye Dam. 1
5-thiazolylmethanol A-87440.0; A-87440.00	414-780-9	38585-74-9	Eye Dam. 1
5-{4-[5-amino-2-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-sulfo-phenylamino]-6-chloro-1,3,5-triazin-2-ylamino}-4-hydroxy-3-(1-sulfo-naphthalen-2-ylazo)-naphthalene-2,7-disulfonicacid sodium salt ROUGE TZ 4075	418-340-7	157707-94-3	Eye Dam. 1
6,13-dichloro-3,10-bis{2-[4-fluoro-6-(2-sulfophenylamino)-1,3,5-triazin-2-ylamino]propylamino}benzo[5,6][1,4]oxazino[2,3-.b.]phenoxazine-4,11-disulphonic acid, lithium-, sodium salt BLEU REN 20	418-000-8	163062-28-0	Eye Dam. 1
6,6'-bis(diazo-5,5', 6,6'-tetrahydro-5,5'-dioxo)[methylene-bis(5-(6-diazo-5,6-dihydro-5-oxo-1-naphthylsulphonyloxy)-6-methyl-2-phenylene]di(naphthalene-1-sulfonate)	441-550-5	-	Self-react. C; Carc. 2
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol; [DBMC]	204-327-1	119-47-1	Repr. 1B
6,7-dihydrodipyrido[1,2-α:2',1'- c]pyrazinediylium dihydroxide	301-467-6	94021-76-8	Acute Tox. 2; STOT RE 1; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
6-(1α,5aβ,8aβ,9-pentahydroxy-7β-isopropyl-2β,5β,8β-trimethylperhydro-8bα,9-epoxy-5,8-ethanocyclopenta[1,2-b]indenyl) pyrrole-2-carboxylate; ryania	239-732-2	15662-33-6	Acute Tox. 4
6-(2,3-dimethylmaleimido)hexyl methacrylate RONACAT RO 305; RONACOAT RO 305	404-870-6	63740-41-0	Skin Sens. 1
6-(nonylamino)-6-oxo-peroxyhexanoic acid ELFADOX EN 3001	406-680-9	104788-63-8	Org. Perox. C; Eye Dam. 1; Skin Sens. 1
6-(phthalimido)peroxyhexanoic acid PAP	410-850-8	128275-31-0	Org. Perox. D; Eye Dam. 1
6-[(C10-C13)-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid	701-118-1	2156592-54-8	Repr. 1B; Eye Irrit. 2
6-[C12-18-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid	701-162-1	-	Repr. 1B
6-[C12-18-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid, sodium and tris(2-hydroxyethyl)ammonium salts	701-271-4	-	Repr. 1B; Eye Irrit. 2
6-dimethylaminohexan-1-ol AF-507; M-3181	404-680-3	1862-07-3	Acute Tox. 4; Skin Corr. 1B
6-docosyloxy-1-hydroxy-4-(1-(4-hydroxy-3-methylphenanthren-1-yl)-3-oxo-2-oxaphenalen-1-yl)naphthalene-2-carboxylic acid ENS 131	404-550-6	130263-41-1	Skin Sens. 1
6-ethyl-5-fluoro-4(3H)-pyrimidone UK-103,442	422-460-5	137234-87-8	Acute Tox. 4
6-fluoro-2-methyl-3-(4-methylthiobenzyl)indene IN-4; INDENE IN-4	405-410-7	41201-60-9	Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
6-glycidyloxynapht-1-yl oxymethyloxirane	429-960-2	27610-48-6	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
6-hydroxy-1-(3-isopropoxypropyl)-4-methyl-2-oxo-5-[4-(phenylazo)phenylazo]-1,2-dihydro-3-pyridinecarbonitrile ARANCIO DISPERSO 149; C.I. DISPERSE ORANGE 149; DISPERS ORANGE 149; DISPERSE ORANGE 149; ORANGE DISPERSE 149; TERASIL GOLDGELB 2RS	400-340-3	85136-74-9	Carc. 1B
6-hydroxyindole IMEXINE OBA	417-020-4	2380-86-1	Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
6-methoxy-m-toluidine; p-cresidine	204-419-1	120-71-8	Carc. 1B; Acute Tox. 4
6-methyl-2,4-bis(methylthio)phenylene-1,3-diamine DM-C-TDA; DMTDA; ETHACURE (R) 300 CURATIVE	403-240-8	106264-79-3	Acute Tox. 4; Skin Sens. 1
6-phenyl-1,3,5-triazine-2,4- diyldiamine; 6-phenyl-1,3,5-triazine-2,4-diamine; benzoguanamine	202-095-6	91-76-9	Acute Tox. 4
7,7,9(or 7,9,9)-trimethyl-4,13-dioxo-3,14-dioxa-5,12-diazahexadecane-1,16-diyl bismethacrylate	276-957-5	72869-86-4	Skin Sens. 1B
7,7-dimethyl-3-oxa-6-azaoctan-1-ol FLEXSORB-SE	400-390-6	87787-67-5	Skin Corr. 1A; Acute Tox. 4
7-[((4,6-dichloro-1,3,5-triazin-2-yl)amino)-4-hydroxy-3-(4-((2-sulfoxy)ethyl)sulfonyl)phenylazo]naphthalene-2-sulfonic acid ORANGE BIREACTIVE DYE	407-050-6	117715-57-8	Skin Sens. 1
7-amino-3-((5-carboxymethyl-4- methyl-1,3-thiazol-2- ylthio)methyl)-8-oxo-5-thia-1- azabicyclo(4.2.0)oct-2-ene-2- carboxylic acid TACS	403-690-5	111298-82-9	Resp. Sens. 1; Skin Sens. 1
7-amino-4-hydroxy-2-naphthalenesulfonic acid, coupled with 5 (or 8) -amino-8 (or 5)-[[4-[[4-[[4-amino-6(or 7)-sulfo-1-naphthyl]azo]phenyl]amino]-3-sulfophenyl]azo]-2-naphthalenesulfonic acid and 4-hydroxy-7-(phenylamino)-2-naphthalenesulfonic acid, sodium salt	424-850-0	189702-72-5	Eye Dam. 1
7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid FLUORCHINOLONCARBONSÄURE	405-050-0	86393-33-1	Acute Tox. 4
7-methoxy-6-(3-morpholin-4-yl-propoxy)-3H-quinazolin-4-one [containing ≥ 0,5 % formamide (EC No 200-842-0)]	429-400-7	199327-61-2	Repr. 1B
7-methylocta-1,6-diene 7-METHYL-1,6-OCTADIENE	404-210-7	42152-47-6	Flam. Liq. 3
7-oxa-3-oxiranylbicyclo [4.1.0]heptane; 1,2-epoxy- 4-epoxyethylcyclohexane; 4-vinylcyclohexene diepoxide	203-437-7	106-87-6	Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 3; Acute Tox. 4
7a-ethyl-3,5-bis(1-methylethyl)-2,3,4,5-tetrahydrooxazolo[3,4-c]-2,3,4,5-tetrahydrooxazole ZOLDINE RD-20	417-140-7	79185-77-6	Skin Irrit. 2
8,8-dimethyl-7-isopropyl-6,10-dioxaspiro[4.5]decane OPALAL	424-030-2	62406-73-9	Skin Irrit. 2
8,9,10-trinorborn-2-yl acrylate	-	10027-06-2	Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
8,9,10-trinorborn-5-ene-2,3-dicarboxylic anhydride	204-957-7	129-64-6	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
8,9-dinorborn-5-ene-2,3-dicarboxylic anhydride	620-411-4	123748-85-6	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
8-amino-7-methylquinoline 8-AMINO-7-METHYLCHINOLIN	412-760-4	5470-82-6	Acute Tox. 4; Skin Sens. 1
8-azaspiro[4.5]decane-7,9-dione 3,3-TETRAMETHYLENE GLUTARIMIDE	427-770-4	1075-89-4	Acute Tox. 3
8-p-menthyl hydroperoxide; p-menthane hydroperoxide	201-281-4	80-47-7	Org. Perox. D; Skin Corr. 1B; Acute Tox. 4
9,9-bis(4-hydroxyphenyl)fluorene BPFL; FLUOREN-BIS-PHENOL	406-950-6	3236-71-3	Eye Irrit. 2; Skin Irrit. 2
9-(2-propenyloxy)tricyclo[5.2.1.0(2,6)]dec-3(or-4-)-ene FLEUROXENE	430-830-2	26912-64-1	Skin Irrit. 2
9-[2-(ethoxycarbonyl) phenyl]-3,6-bis(ethylamino)–2,7-dimethylxanthylium chloride; Basic Red 1	213-584-9	989-38-8	Acute Tox. 3; Eye Dam. 1; Skin Sens. 1
9-vinylcarbazole	216-055-0	1484-13-5	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
[(1-methyl-1,2-ethanediyl)bis[nitrilobis(methylene)]]tetrakis(phosphonic acid)	421-940-1	28698-31-9	Eye Dam. 1
[(4S, 5S)-4-benzyl-2-oxo-5-oxazolidinyl]methyl 4-nitrobenzenesulfonate	416-360-0	162221-28-5	Skin Sens. 1
[(dimethylsilylene)bis((1,2,3,3a,7a-η)-1H-inden-1-ylidene)dimethyl]hafnium M1	422-060-0	137390-08-0	Acute Tox. 2
[(m-tolyloxy)methyl]oxirane	218-575-3	2186-25-6	Muta. 2; Skin Irrit. 2; Skin Sens. 1
[(p-tolyloxy)methyl]oxirane	218-574-8	2186-24-5	Muta. 2; Skin Irrit. 2; Skin Sens. 1
[(tolyloxy)methyl]oxirane; cresyl glycidyl ether	247-711-4	26447-14-3	Muta. 2; Skin Irrit. 2; Skin Sens. 1
[1R-(1-α, 2β,5α)]-mono[5-methyl-2-(1-methylethyl)cyclohexyl]butanedioate	426-890-4	77341-67-4	Eye Dam. 1

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EU-SAFETY_HEALTH_WORK-PREAMBLE

EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

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Last updated 23 April 2024. Database contains 4691 unique substances/entries.

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