EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

Last updated 16 April 2024. Database contains 4691 unique substances/entries.
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215-154-6
1307-96-6
Acute Tox. 4; Skin Sens. 1
233-334-2
10124-43-3
Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 4; Resp. Sens. 1; Skin Sens. 1
215-273-3
1317-42-6
Skin Sens. 1
200-598-5
64-86-8
Muta. 1B; Acute Tox. 2
200-673-2
67-97-0
Acute Tox. 2; STOT RE 1
231-842-9
7758-89-6
Acute Tox. 4
243-815-9
20427-59-2
Acute Tox. 2; Acute Tox. 4; Eye Dam. 1
231-847-6
7758-98-7
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
235-113-6
12069-69-1
Acute Tox. 4; Eye Irrit. 2
204-810-7
126-90-9
Skin Sens. 1B
201-378-1
81-82-3
STOT RE 2
204-195-5
117-52-2
Acute Tox. 3; STOT RE 1
200-285-3
56-72-4
Acute Tox. 2; Acute Tox. 4
227-424-0
5836-29-3
Repr. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1
The distillate of coal tar produced by the high temperature carbonization of bituminous coal. It consists primarily of aromatic hydrocarbons, tar acids and tar bases.
232-287-5
8001-58-9
Carc. 1B
A complex combination of hydrocarbons obtained by the distillation of coal tar. It consists primarily of aromatic hydrocarbons and may contain appreciable quantities of tar acids and tar bases. It distills at the approximate range of 200°C to 325°C (392°F to 617°F).
263-047-8
61789-28-4
Carc. 1B
The oil remaining after removal by a crystallization process of acenaphthene from acenaphthene oil from coal tar. Composed primarily of naphthalene and alkylnaphthalenes.
292-606-9
90640-85-0
Carc. 1B
A complex combination of hydrocarbons produced by the distillation of coal tar and boiling in the range of approximately 240°C to 280°C (464°F to 536°F). Composed primarily of acenaphthene, naphthalene and alkyl naphthalene.
292-605-3
90640-84-9
Carc. 1B
The high-boiling distillation fraction obtained from the high temperature carbonization of bituminous coal which is further refined to remove excess crystalline salts. It consists primarily of creosote oil with some of the normal polynuclear aromatic salts, which are components of coal tar distillates, removed. It is crystal free at approximately 5°C (41°F).
274-565-9
70321-79-8
Carc. 1B
The low-boiling distillation fraction obtained from the high temperature carbonization of bituminous coal, which is further refined to remove excess crystalline salts. It consists primarily of creosote oil with some of the normal polynuclear aromatic salts, which are components of coal tar distillate, removed. It is crystal free at approximately 38°C (100°F).
274-566-4
70321-80-1
Carc. 1B
208-622-6
535-89-7
Acute Tox. 2
224-030-0
4170-30-3
Flam. Liq. 2; Muta. 2; Acute Tox. 2; Acute Tox. 3; STOT RE 2; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
231-720-5
7700-17-6
Acute Tox. 3
206-083-1
299-86-5
Acute Tox. 4
202-704-5
98-82-8
Flam. Liq. 3; Carc. 1B; Asp. Tox. 1; STOT SE 3
206-992-3
420-04-2
Carc. 2; Repr. 2; Acute Tox. 3; STOT RE 2; Skin Corr. 1; Skin Sens. 1; Eye Dam. 1
244-544-9
21725-46-2
Acute Tox. 4
220-130-3
2636-26-2
Acute Tox. 4
223-099-4
3734-95-0
Acute Tox. 2; Acute Tox. 3
203-806-2
110-82-7
Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
201-604-9
85-42-7
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
203-630-6
108-93-0
Acute Tox. 4; STOT SE 3; Skin Irrit. 2
203-631-1
108-94-1
Flam. Liq. 3; Acute Tox. 4
235-527-7
12262-58-7
Org. Perox. A; Skin Corr. 1B; Acute Tox. 4
235-527-7
12262-58-7
Org. Perox. C; Acute Tox. 4; Skin Corr. 1B
200-636-0
66-81-9
Muta. 2; Repr. 1B; Acute Tox. 2
221-319-3
3066-71-5
STOT SE 3; Skin Irrit. 2
203-629-0
108-91-8
Flam. Liq. 3; Repr. 2; Acute Tox. 4; Skin Corr. 1B
220-279-4
2699-11-8
Org. Perox. C; Acute Tox. 4; Skin Corr. 1B
220-279-4
2699-11-8
Org. Perox. A; Skin Corr. 1B; Acute Tox. 4
206-016-6
287-92-3
Flam. Liq. 2
227-964-7
6053-68-5
Eye Irrit. 2; STOT SE 3
204-435-9
120-92-3
Flam. Liq. 3; Eye Irrit. 2; Skin Irrit. 2
200-847-8
75-19-4
Flam. Gas 1; Press. Gas
269-855-7
68359-37-5
Lact.; Acute Tox. 2; STOT SE 1
236-049-1
13121-70-5
Acute Tox. 4
261-043-0
57966-95-7
Repr. 2; Acute Tox. 4; STOT RE 2; Skin Sens. 1
257-842-9
52315-07-8
Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
257-842-9
52315-07-8
Acute Tox. 4; STOT SE 3; STOT RE 2
274-050-9
69581-33-5
Acute Tox. 3; Acute Tox. 4
218-827-2
2244-16-8
Skin Sens. 1
204-828-5
127-20-8
Skin Irrit. 2; Eye Dam. 1
200-923-0
75-99-0
Skin Irrit. 2; Eye Dam. 1
216-485-9
1596-84-5
Carc. 2
201-248-4
80-08-0
Acute Tox. 4
208-576-7
533-74-4
Acute Tox. 4; Eye Irrit. 2
200-024-3
50-29-3
Carc. 2; Acute Tox. 3; STOT RE 1
206-376-4
334-48-5
Skin Irrit. 2; Eye Irrit. 2
258-256-6
52918-63-5
Acute Tox. 3
211-666-9
682-80-4
Acute Tox. 2; Acute Tox. 3
219-971-9
2587-90-8
Acute Tox. 2; Acute Tox. 3
206-053-8
298-03-3
Acute Tox. 1; Acute Tox. 2
212-758-1
867-27-6
Acute Tox. 3
204-801-8
126-75-0
Acute Tox. 1; Acute Tox. 2
213-052-6
919-86-8
Acute Tox. 3
241-109-5
17040-19-6
Acute Tox. 3; Acute Tox. 4
237-198-5
13684-56-5
Repr. 2
213-800-1
1014-69-3
Acute Tox. 4
204-424-9
120-78-5
Skin Sens. 1
218-961-1
2303-16-4
Carc. 2; Acute Tox. 4
204-697-4
124-40-3
Flam. Liq. 1; Acute Tox. 4; Skin Corr. 1B
204-697-4
124-40-3
Flam. Gas 1; Press. Gas; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
205-575-3
142-96-1
Flam. Liq. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
203-921-8
111-92-2
Flam. Liq. 3; Acute Tox. 2; Acute Tox. 3; Skin Corr. 1B; Eye Dam. 1
205-017-9
131-18-0
Repr. 1B
203-733-6
110-05-4
Org. Perox. E; Flam. Liq. 2; Muta. 2
233-689-3
10311-84-9
Acute Tox. 2; Acute Tox. 3
205-016-3
131-17-9
Acute Tox. 4
234-454-8
12004-35-2
Carc. 1A; STOT RE 1; Skin Sens. 1
240-973-0
16919-58-7
Acute Tox. 3; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
239-793-5
15699-18-0
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Acute Tox. 4; Resp. Sens. 1; Skin Sens. 1
231-786-5
7727-54-0
Ox. Sol. 3; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
237-499-1
13820-41-2
Acute Tox. 3; Skin Irrit. 2; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
215-116-9
1303-28-2
Carc. 1A; Acute Tox. 3
215-481-4
1327-53-3
Carc. 1A; Acute Tox. 2; Skin Corr. 1B
206-373-8
333-41-5
Acute Tox. 4
206-382-7
334-88-3
Carc. 1B
200-181-8
53-70-3
Carc. 1B
205-878-0
189-64-0
Carc. 1B; Muta. 2
205-886-4
191-30-0
Carc. 1B; Muta. 2
202-327-6
94-36-0
Org. Perox. B; Eye Irrit. 2; Skin Sens. 1
215-125-8
1303-86-2
Repr. 1B
200-824-2
74-95-3
Acute Tox. 4
201-557-4
84-74-2
Repr. 1B
245-152-0
22673-19-4
Repr. 1B; STOT RE 1
220-481-2
2781-10-4
Muta. 2; Repr. 1B; STOT RE 1
213-928-8
1067-33-0
Muta. 2; Repr. 1B; STOT RE 1
211-670-0
683-18-1
Muta. 2; Repr. 1B; Acute Tox. 2; Acute Tox. 3; Acute Tox. 4; STOT RE 1; Skin Corr. 1B
201-039-8
77-58-7
Muta. 2; Repr. 1B; STOT RE 1
201-077-5
78-04-6
Muta. 2; Repr. 1B; Acute Tox. 2; Acute Tox. 4; STOT RE 1; Skin Corr. 1; Eye Dam. 1
212-449-1
818-08-6
Muta. 2; Repr. 1B; Acute Tox. 3; STOT RE 1; Skin Irrit. 2; Eye Dam. 1
217-635-6
1918-00-9
Acute Tox. 4; Eye Dam. 1
214-787-5
1194-65-6
Acute Tox. 4
202-564-5
97-17-6
Acute Tox. 4
214-118-7
1085-98-9
Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
204-210-5
117-80-6
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
220-487-5
2782-57-2
Ox. Sol. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
201-207-0
79-43-6
Skin Corr. 1A
201-199-9
79-36-7
Skin Corr. 1A
222-583-2
3542-36-7
Repr. 1B; Acute Tox. 2; STOT RE 1
200-838-9
75-09-2
Carc. 2
202-567-1
97-23-4
Acute Tox. 4; Eye Irrit. 2
204-390-5
120-36-5
Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
200-547-7
62-73-7
Acute Tox. 2; Acute Tox. 3; Skin Sens. 1
246-356-2
24613-89-6
Ox. Sol. 1; Carc. 1B; Skin Corr. 1A; Skin Sens. 1
257-141-8
51338-27-3
Acute Tox. 4; Skin Sens. 1
204-082-0
115-32-2
Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
215-572-9
1332-65-6
Acute Tox. 4; Acute Tox. 3
215-270-7
1317-39-1
Acute Tox. 4; Eye Dam. 1
200-632-9
66-76-2
STOT RE 1; Acute Tox. 4
205-494-3
141-66-2
Acute Tox. 2; Acute Tox. 3
201-545-9
84-61-7
Repr. 1B; Skin Sens. 1
202-980-7
101-83-7
Acute Tox. 4; Skin Corr. 1B
221-515-9
3129-91-7
Acute Tox. 4
208-704-1
538-75-0
Acute Tox. 3; Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
230-525-2
7173-51-5
Acute Tox. 4; Skin Corr. 1B
200-484-5
60-57-1
Carc. 2; Acute Tox. 1; Acute Tox. 3; STOT RE 1
274-460-8
70225-14-8
Carc. 2; Repr. 1B; STOT RE 1; Acute Tox. 4; Lact.
258-526-3
53404-23-2
Acute Tox. 4
200-467-2
60-29-7
Flam. Liq. 1; Acute Tox. 4; STOT SE 3
200-589-6
64-67-5
Carc. 1B; Muta. 1B; Acute Tox. 4; Skin Corr. 1B
203-716-3
109-89-7
Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1A
201-798-5
88-10-8
Carc. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
211-000-7
627-44-1
Acute Tox. 2; Acute Tox. 1; STOT RE 2
270-877-4
68479-98-1
Acute Tox. 4; STOT RE 2; Eye Irrit. 2
209-161-3
557-20-0
Pyr. Liq. 1; Water-react. 1; Skin Corr. 1B
200-760-5
71-63-6
Acute Tox. 3; STOT RE 2
201-559-5
84-75-3
Repr. 1B
201-553-2
84-69-5
Repr. 1B
276-090-2
71850-09-4
Repr. 1B
248-523-5
27554-26-3
Repr. 1B
210-088-4
605-50-5
Repr. 1B
203-560-6
108-20-3
Flam. Liq. 2; STOT SE 3
203-558-5
108-18-9
Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1B
211-617-1
674-82-8
Flam. Liq. 3; Acute Tox. 4
203-326-3
105-74-8
Org. Perox. D
204-076-8
115-26-4
Acute Tox. 1; Acute Tox. 2
262-784-2
61432-55-1
Acute Tox. 4
233-307-5
10112-91-1
Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
215-629-8
1335-31-5
Expl. 1.1; Acute Tox. 3; STOT RE 2
256-625-6
50563-36-5
Acute Tox. 4; Skin Sens. 1
200-480-3
60-51-5
Acute Tox. 4
210-478-4
616-38-6
Flam. Liq. 2
210-871-0
624-92-0
Flam. Liq. 2; Acute Tox. 3; STOT SE 3; STOT SE 1; Eye Irrit. 2; Skin Sens. 1
204-065-8
115-10-6
Flam. Gas 1; Press. Gas
242-555-3
18755-43-6
Muta. 1B; Repr. 1B
201-058-1
77-78-1
Carc. 1B; Muta. 2; Acute Tox. 2; Acute Tox. 3; Skin Corr. 1B; Skin Sens. 1
201-208-6
79-44-7
Carc. 1B; Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
200-901-0
75-78-5
Flam. Liq. 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
203-508-2
107-64-2
Eye Dam. 1
209-805-3
593-74-8
Acute Tox. 2; Acute Tox. 1; STOT RE 2
200-549-8
62-75-9
Carc. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1
236-412-4
13360-57-1
Carc. 1B; Acute Tox. 2; Acute Tox. 4; Skin Corr. 1B
212-039-2
753-73-1
Repr. 2; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Skin Corr. 1B
208-884-1
544-97-8
Pyr. Liq. 1; Water-react. 1; Skin Corr. 1B
215-993-8
1468-37-7
Acute Tox. 4
205-042-5
131-89-5
Acute Tox. 3
234-494-6
12007-01-1
Carc. 1A; STOT RE 1; Skin Sens. 1
238-426-6
14448-18-1
Carc. 1A; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
238-946-3
14874-78-3
Carc. 1A; STOT RE 1; Skin Sens. 1
237-411-1
13775-54-7
Carc. 1A; STOT RE 1; Skin Sens. 1
234-828-0
12035-64-2
Carc. 1A; STOT RE 1; Skin Sens. 1
235-033-1
12059-14-2
Carc. 1A; STOT RE 1; Skin Sens. 1
215-217-8
1314-06-3
Carc. 1A; STOT RE 1; Skin Sens. 1
246-673-6
25154-54-5
Acute Tox. 2; Acute Tox. 1; STOT RE 2
234-126-4
10544-72-6
Press. Gas; Ox. Gas 1; Acute Tox. 2; Skin Corr. 1B
247-096-2
25550-58-7
Acute Tox. 3; STOT RE 2
246-836-1
25321-14-6
Carc. 1B; Muta. 2; Repr. 2; Acute Tox. 3; STOT RE 2
213-546-1
973-21-7
Acute Tox. 3
254-408-0
39300-45-3
Repr. 1B; Acute Tox. 4; STOT RE 2; Skin Irrit. 2; Skin Sens. 1
201-861-7
88-85-7
Repr. 1B; Acute Tox. 3; Eye Irrit. 2
215-813-8
1420-07-1
Repr. 1B; Acute Tox. 2; Acute Tox. 3
222-883-3
3648-18-8
Repr. 1B; STOT RE 1
223-292-3
3811-49-2
Acute Tox. 3; STOT SE 1
230-253-4
6988-21-2
Acute Tox. 3
201-107-7
78-34-2
Acute Tox. 2; Acute Tox. 3
201-434-5
82-66-6
Acute Tox. 2; STOT RE 1
213-482-4
957-51-7
Acute Tox. 4
251-084-2
32534-81-9
STOT RE 2; Lact.
278-355-8
75980-60-8
Repr. 1B; Skin Sens. 1B
204-539-4
122-39-4
Acute Tox. 3; STOT RE 2
251-087-9
32536-52-0
Repr. 1B
215-242-4
1314-80-3
Flam. Sol. 1; Water-react. 1; Acute Tox. 4
220-639-0
2844-92-0
Expl. 1.1; Acute Tox. 2; Acute Tox. 1; STOT RE 2
240-979-3
16921-30-5
Acute Tox. 3; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
231-781-8
7727-21-1
Ox. Sol. 3; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
215-197-0
1312-73-8
Skin Corr. 1B
233-050-9
10025-99-7
Acute Tox. 3; Skin Irrit. 2; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
203-869-6
111-43-3
Flam. Liq. 2; STOT SE 3
205-565-9
142-84-7
Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1A

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