EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

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Last updated 24 April 2024. Database contains 4691 unique substances/entries.
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Substance Name
EC No.
CAS No.
EU CLP (1272/2008)
EU_BA Directive 2000/54/EC
1,1-diethoxyethane; acetal
203-310-6
105-57-7
Flam. Liq. 2; Eye Irrit. 2; Skin Irrit. 2
1,1-diisopropoxycyclohexane
413-740-8
1132-95-2
Skin Corr. 1B
1,1-dimethylethyl 4'-(bromomethyl)biphenyl-2-carboxylate
442-850-9
114772-40-6
Skin Sens. 1
1,2,3,4-tetrahydronaphthalene
204-340-2
119-64-2
Eye Irrit. 2; Skin Irrit. 2
1,2,4-trichlorobenzene
204-428-0
120-82-1
Acute Tox. 4; Skin Irrit. 2
1,2-bis(2-methoxyethoxy)ethane; TEGDME; triethylene glycol dimethyl ether; triglyme
203-977-3
112-49-2
Repr. 1B
1,2-bis[4-fluoro-6-{4-sulfo-5-(2-(4-sulfonaphtalene-3-ylazo)-1-hydroxy-3,6-disulfo-8-aminonaphthalene-7-ylazo)phenylamino}-1,3,5-triazin-2ylamino]ethane; x-sodium, y-potassium salts x = 7,755 y =0,245
REACTIVE NAVY DER 7678
417-610-1
155522-09-1
Skin Sens. 1
1,2-diacetoxybut-3-ene
3,4-DIACETOXY-1-BUTENE
421-720-5
18085-02-4
Acute Tox. 4
1,2-dibromoethane
203-444-5
106-93-4
Carc. 1B; Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
1,2-dichloroethane; ethylene dichloride
203-458-1
107-06-2
Flam. Liq. 2; Carc. 1B; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
1,2-diethoxypropane
1,2-DIETHOXYPROPANE; DIETHOXY-1,2-PROPANE
412-180-1
10221-57-5
Flam. Liq. 2
1,2-dihydroxybenzene; pyrocatechol
204-427-5
120-80-9
Carc. 1B; Muta. 2; Acute Tox. 3; Eye Irrit. 2; Skin Irrit. 2
1,2-dimethoxyethane; ethylene glycol dimethyl ether; EGDME
203-794-9
110-71-4
Flam. Liq. 2; Repr. 1B; Acute Tox. 4
1,2-dimethylimidazole
217-101-2
1739-84-0
Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
1,2-epoxybutane
203-438-2
106-88-7
Flam. Liq. 2; Carc. 2; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Irrit. 2
1,3,5-triazine-2,4,6-triamine; melamine
203-615-4
108-78-1
Carc. 2; STOT RE 2
1,3,5-trioxan; trioxymethylene
203-812-5
110-88-3
Flam. Sol. 1; Repr. 2; STOT SE 3
1,3-bis(2,3-epoxypropoxy)-2,2-dimethylpropane
241-536-7
17557-23-2
Skin Irrit. 2; Skin Sens. 1
1,3-bis(3-methyl-2,5-dioxo-1H-pyrrolinylmethyl)benzene
PERKALINK 900
412-570-1
119462-56-5
STOT RE 2; Eye Dam. 1; Skin Sens. 1
1,3-bis(dimethylcarbamoyl)-imidazolium chloride
420-930-4
135756-61-5
Acute Tox. 4; Eye Dam. 1
1,3-bis[12-hydroxy-octadecamide-N-methylene]-benzene
423-300-7
128554-52-9
Skin Sens. 1
1,3-bis{6-fluoro-4-[1,5-disulfo-4-(3-aminocarbonyl-1-ethyl-6-hydroxy-4-methyl-pyrid-2-on-5-ylazo)-phenyl-2-ylamino]-1,3,5-triazin-2-ylamino}propane lithium-, sodium salt
JAUNE REACTIF MUB 151
415-100-3
149850-29-3
Skin Sens. 1
1,3-butadiene; buta-1,3-diene
203-450-8
106-99-0
Flam. Gas 1; Press. Gas; Carc. 1A; Muta. 1B
1,3-di(prop-2,2-diyl)benzene bis(neodecanoylperoxide)
DIPND-50-AL (META)
420-060-5
117663-11-3
Flam. Liq. 3; Org. Perox. D
1,3-dichloro-4-fluorobenzene
1,3-DICHLOR-4-FLUORBENZOL; B-7
406-160-1
1435-48-9
Acute Tox. 4; STOT RE 2; Skin Irrit. 2
1,3-dimethyl-1,3-bis(trimethylsilyl)urea
UTMS
414-180-7
10218-17-4
Acute Tox. 4; Skin Irrit. 2
1,3-diphenylguanidine
203-002-1
102-06-7
Repr. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
1,3-propanesultone; 1,2-oxathiolane 2,2-dioxide
214-317-9
1120-71-4
Carc. 1B; Acute Tox. 4
1,4,5,6,7,7-hexachlorobicyclo [2,2,1]hept-5-ene-2,3-dicarboxylicanhydride chlorendic anhydride
204-077-3
115-27-5
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
1,4,7,10-tetraazacyclododecane disulfate
AZA-KRONE-DISULFAT; SQ 84,042F
412-080-8
112193-77-8
Acute Tox. 4; STOT SE 3; Eye Dam. 1
1,4-bis[(vinyloxy)methyl]cyclohexane
RAPICURE CHVE
413-370-7
17351-75-6
Skin Sens. 1
1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene
CA 946 A
415-580-4
130841-23-5
Acute Tox. 4; Skin Sens. 1
1,4-dichlorobenzene; p-dichlorobenzene
203-400-5
106-46-7
Carc. 2; Eye Irrit. 2
1,4-Dicyano-2,3,5,6-tetra-chloro-benzene
TETRACHLOROTEREPHTHALONITRILE
401-550-8
1897-41-2
Skin Sens. 1
1,4-dihydroxybenzene; hydroquinone; quinol
204-617-8
123-31-9
Carc. 2; Muta. 2; Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
1,4-dinitrobenzene
202-833-7
100-25-4
Acute Tox. 2; Acute Tox. 1; STOT RE 2
1,4-dioxane
204-661-8
123-91-1
Flam. Liq. 2; Carc. 1B; Eye Irrit. 2; STOT SE 3
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate
HÄRTER VERSUCHSPRODUKT LS 2959E; HÄRTER VP LS 2959E
411-700-4
140921-24-0
Skin Sens. 1
1,7,7-trimethylbicyclo(2,2,1)hept-2-yl thiocyanatoacetate; isobornyl thiocyanoacetate
204-081-5
115-31-1
Acute Tox. 4
1-((2-quinolinyl-carbonyl)oxy)-2,5-pyrrolidinedione
PTH-SUCCINIMIDESTER
418-630-3
136465-99-1
Eye Dam. 1; Skin Sens. 1
1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanone methanesulfonate
431-010-7
154486-26-7
Acute Tox. 4; Eye Dam. 1
1-(2-(ethyl(4-(4-(4-(4-(ethyl(2-pyridinoethyl)amino)-2-methylphenylazo)benzoylamino)-phenylazo)-3-methylphenyl)amino)ethyl)-pyridinium dichloride
ORANGE DK 2764
420-950-3
163831-67-2
Eye Dam. 1
1-(2-hydroxyethyl)-1H-pyrazol-4,5-diyldiammoniumsulfate
PYRAZOL P5; PYRAZOLE DHE
429-300-3
155601-30-2
Eye Dam. 1; Skin Sens. 1
1-(3-(4-fluorophenoxy)propyl)3-methoxy-4-piperidinone
T1314
411-500-7
116256-11-2
Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
1-(3-cyclopentyloxy-4-methoxyphenyl)-4-oxo-cyclohexanecarbonitrile
427-450-4
152630-47-2
Acute Tox. 4; STOT RE 2; Skin Sens. 1
1-(3-iodo-4-aminobenzyl)-1H-1,2,4-triazole
IODOANILINE TRIAZOLE
419-540-7
160194-26-3
Acute Tox. 4; Skin Sens. 1
1-(3-methoxypropyl)-4-piperidinamine
431-950-8
179474-79-4
Acute Tox. 4; Skin Corr. 1B
1-(3-phenylpropyl)-2-methylpyridinium bromide
NT-8
405-930-4
10551-42-5
Acute Tox. 4; Eye Irrit. 2
1-(mercaptomethyl)cyclopropylacetic acid
420-240-3
162515-68-6
Skin Corr. 1B; Acute Tox. 4; Skin Sens. 1
1-(N,N-dimethylcarbamoyl)-3-tert-butyl-5-carbethoxymethylthio-1H-1,2,4-triazole
TRIAZAMATE
411-650-3
110895-43-7
Acute Tox. 3
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