EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

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Last updated 23 April 2024. Database contains 4691 unique substances/entries.
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Substance Name
EC No.
CAS No.
EU CLP (1272/2008)
EU_BA Directive 2000/54/EC
1-ethoxy-2,3-difluorobenzene
1-ETHOXY-2,3-DIFLUORBENZOL; 1-ETHOXY-2,3-DIFLUOROBENZENE; 2,3-DIFLUOROPHENETOL; DIPHOL
441-000-4
121219-07-6
Acute Tox. 4
1-ethyl-5,6,7,8-tetrahydroquinolinium tosylate
419-570-0
195006-58-7
Acute Tox. 4
1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide
424-160-1
139481-22-4
Acute Tox. 4
1-naphthylamine
205-138-7
134-32-7
Acute Tox. 4
1-phenyl-3-pyrazolidone
202-155-1
92-43-3
Acute Tox. 4
12-hydroxyoctadecanoic acid, reaction products with 1,3-benzenedimethanamine and hexamethylenediamine
432-840-2
220926-97-6
Acute Tox. 4
2,2' -oxybisethanol; diethylene glycol
203-872-2
111-46-6
Acute Tox. 4
2,2,4-trimethyl-4-phenyl-butane-nitrile
KHUSINIL
422-580-8
75490-39-0
Acute Tox. 4
2,3,6-TBA (ISO); 2,3,6-trichlorobenzoic acid
200-026-4
50-31-7
Acute Tox. 4
2,4-DB (ISO); 4-(2,4-dichlorophenoxy)butyric acid
202-366-9
94-82-6
Acute Tox. 4
2,5-dihydroxy-5-methyl-3-(morpholin-4-yl)-2-cyclopenten-1-one
430-170-5
114625-74-0
Acute Tox. 4
2,6-diethylaniline
209-445-7
579-66-8
Acute Tox. 4
2-(2-bromoethoxy)anisole
GUAIACOL-O-ETHYLBROMIDE
402-010-4
4463-59-6
Acute Tox. 4
2-(2-iodoethyl)-1,3-propanediol diacetate
BRL 47539
411-780-0
127047-77-2
Acute Tox. 4
2-[(4-chloro-2-nitrophenyl)amino]ethanol
CHLORGELB; HC YELLOW 12
413-280-8
59320-13-7
Acute Tox. 4
2-amino-4,6-dinitrophenol; picramic acid;2-amino-4,6-dinitrophenol; picramic acid [≥ 20 % water]
202-544-6
96-91-3
Acute Tox. 4
2-amino-4-chloro-6-methoxypyrimidine
DPX N6186; N 6186
410-050-9
5734-64-5
Acute Tox. 4
2-amino-6-ethoxy-4-methylamino-1,3,5-triazine
DPX-D-7556
403-580-7
62096-63-3
Acute Tox. 4
2-benzyl-2-methyl-3-butenitrile
CITROWANIL B
407-870-4
97384-48-0
Acute Tox. 4
2-bromo-4,6-difluoroaniline
429-430-0
444-14-4
Acute Tox. 4
2-butoxyethyl acetate; butylglycol acetate
203-933-3
112-07-2
Acute Tox. 4
2-chloro-4-nitroaniline
204-502-2
121-87-9
Acute Tox. 4
2-chlorophenol
202-433-2
95-57-8
Acute Tox. 4
2-chlorotoluene
202-424-3
95-49-8
Acute Tox. 4
2-cyclohexylidene-2-phenylacetonitrile
423-740-1
10461-98-0
Acute Tox. 4
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