EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

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Last updated 25 April 2024. Database contains 4691 unique substances/entries.
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Substance Name
EC No.
CAS No.
EU CLP (1272/2008)
EU_BA Directive 2000/54/EC
digitoxin
200-760-5
71-63-6
Acute Tox. 3; STOT RE 2
dihexyl phthalate
201-559-5
84-75-3
Repr. 1B
diisobutyl phthalate
201-553-2
84-69-5
Repr. 1B
diisohexyl phthalate
276-090-2
71850-09-4
Repr. 1B
diisooctyl phthalate
248-523-5
27554-26-3
Repr. 1B
diisopentylphthalate
210-088-4
605-50-5
Repr. 1B
diisopropyl ether
203-560-6
108-20-3
Flam. Liq. 2; STOT SE 3
diisopropylamine
203-558-5
108-18-9
Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1B
diketene; diketen
211-617-1
674-82-8
Flam. Liq. 3; Acute Tox. 4
dilauroyl peroxide
203-326-3
105-74-8
Org. Perox. D
dilithium 6-acetamido-4-hydroxy-3-(4-((2-sulphonatooxy)ethylsulphonyl) phenylazo)naphthalene-2-sulphonate
REACTIVE ORANGE F-64 258 FW
401-010-1
106027-83-2
Skin Sens. 1
dilithium disodium (5,5'-diamino-(μ-4,4'-dihydroxy-1:2κ-2,O4,O4',-3,3'-[3,3'-dihydroxy-1:2-κ-2-O3,O3'-biphenyl-4,4'-ylenebisazo-1:2-(N3, N4-η:N3', N4'-η)]-dinaphthalene-2,7-disulfonato(8)))dicuprate(2-)
BLUE GS 1259 R5
407-230-4
126637-70-5
Acute Tox. 4; Skin Sens. 1
dimefox (ISO); tetramethylphosphorodiamidic fluoride
204-076-8
115-26-4
Acute Tox. 1; Acute Tox. 2
dimepiperate (ISO);S-(1-methyl-1-phenylethyl) piperidine-1-carbothioate
262-784-2
61432-55-1
Acute Tox. 4
dimercury dichloride; mercurous chloride; calomel
233-307-5
10112-91-1
Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
dimercury dicyanide oxide; mercuric oxycyanide
215-629-8
1335-31-5
Expl. 1.1; Acute Tox. 3; STOT RE 2
dimethachlor (ISO); 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide
256-625-6
50563-36-5
Acute Tox. 4; Skin Sens. 1
dimethenamid-P (ISO); 2-chloro-N-(2,4-dimethyl-3- thienyl)-N-[(2S)-1-methoxypropan-2-yl]acetamide
605-329-9
163515-14-8
Acute Tox. 4; Skin Sens. 1
dimethoate (ISO); O, O-dimethyl methylcarbamoylmethyl phosphorodithioate
200-480-3
60-51-5
Acute Tox. 4
dimethomorph (ISO); (E,Z)-4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl) acryloyl)morpholine
404-200-2
110488-70-5
Repr. 1B
dimethyl (2S)-2-hydroxysuccinate
432-310-0
617-55-0
Flam. Liq. 3; Eye Dam. 1; Skin Sens. 1
dimethyl (3-methyl-4-(5-nitro-3-ethoxycarbonyl-2-thienyl)azo)phenylnitrilodipropionate
C.I. DISPERSE BLUE 356
400-460-6
118578-14-6
Skin Sens. 1
dimethyl 4-(methylthio)phenyl phosphate
620-379-1
3254-63-5
Acute Tox. 1; Acute Tox. 2
dimethyl carbonate
210-478-4
616-38-6
Flam. Liq. 2
dimethyl disulphide
210-871-0
624-92-0
Flam. Liq. 2; Acute Tox. 3; STOT SE 3; STOT SE 1; Eye Irrit. 2; Skin Sens. 1
dimethyl ether
204-065-8
115-10-6
Flam. Gas 1; Press. Gas
dimethyl propylphosphonate
242-555-3
18755-43-6
Muta. 1B; Repr. 1B
dimethyl sulphate
201-058-1
77-78-1
Carc. 1B; Muta. 2; Acute Tox. 2; Acute Tox. 3; Skin Corr. 1B; Skin Sens. 1
dimethyl[2S, 2S']-6,6,6'6'-tetramethoxy-2,2'-[N, N'-bis(trifluoracetyl)-S, S'-bi(L-homocysteinyl) diimino]dihexanoate
432-860-1
255387-46-3
Skin Sens. 1
dimethylcarbamoyl chloride
201-208-6
79-44-7
Carc. 1B; Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
dimethyldichlorosilane
200-901-0
75-78-5
Flam. Liq. 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
dimethyldioctadecylammonium chloride; DODMAC
203-508-2
107-64-2
Eye Dam. 1
dimethyldioctadecylammonium hydrogen sulfate
SUMQUAT 6040
404-050-8
123312-54-9
Eye Irrit. 2
dimethylhexanoic acid nickelsalt
301-323-2
93983-68-7
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
dimethylmercury
209-805-3
593-74-8
Acute Tox. 2; Acute Tox. 1; STOT RE 2
dimethylnitrosoamine; N-nitrosodimethylamine
200-549-8
62-75-9
Carc. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1
dimethylsulfamoylchloride
236-412-4
13360-57-1
Carc. 1B; Acute Tox. 2; Acute Tox. 4; Skin Corr. 1B
dimethyltin dichloride
212-039-2
753-73-1
Repr. 2; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Skin Corr. 1B
dimethylzinc
208-884-1
544-97-8
Pyr. Liq. 1; Water-react. 1; Skin Corr. 1B
dimexano(ISO); bis(methoxythiocarbonyl) disulphide
215-993-8
1468-37-7
Acute Tox. 4
dimoxystrobin (ISO); (2E)-2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-(methoxyimino)-N-methylacetamide; (E)-2-(methoxyimino)-N-methyl-2-[α-(2,5-xylyloxy)-o-tolyl]acetamide
604-712-8
149961-52-4
Carc. 2; Repr. 2; Acute Tox. 4
dinex (ISO); 2-cyclohexyl-4,6-dinitrophenol
205-042-5
131-89-5
Acute Tox. 3
dinickel boride
234-494-6
12007-01-1
Carc. 1A; STOT RE 1; Skin Sens. 1
dinickel diphosphate
238-426-6
14448-18-1
Carc. 1A; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
dinickel hexacyanoferrate
238-946-3
14874-78-3
Carc. 1A; STOT RE 1; Skin Sens. 1
dinickel orthosilicate
237-411-1
13775-54-7
Carc. 1A; STOT RE 1; Skin Sens. 1
dinickel phosphide
234-828-0
12035-64-2
Carc. 1A; STOT RE 1; Skin Sens. 1
dinickel silicide
235-033-1
12059-14-2
Carc. 1A; STOT RE 1; Skin Sens. 1
dinickel trioxide
215-217-8
1314-06-3
Carc. 1A; STOT RE 1; Skin Sens. 1
diniconazole (ISO);(E)-β-[(2,4-dichlorophenyl)methylene]-α-(1,1-dimethylethyl)-1H—1,2,4-triazol-1- ethanol;(E)-(RS)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1H—1,2,4- triazol-1-yl)pent-1-en-3-ol
617-485-5
76714-88-0
Acute Tox. 4
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