EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1

Active Implantable Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007

This list contains hazardous substances for purposes of Directive 90/385/EEC on active implantable medical devices, particularly as regards Article 3 and Annex I (Essential Requirements). This non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Please note that Regulation (EU) 2017/745 on medical devices has repealed Directive 90/385/EEC and begun to apply from 26 May 2021. Nevertheless, Article 120 of the Regulation provides for a transitional period allowing medical devices, under specified conditions (e.g., placed on the market prior to 26 May 2021), to continue to comply with the Directive. In accordance with the fourth paragraph of Article 120, this period ends 26 May 2025.

Last updated 27 May 2024. Database contains 4753 unique substances/entries.
Filter the list

221-221-0
3033-77-0
Carc. 1B; Muta. 2; Repr. 2; Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1
223-383-8
3864-99-1
yes
254-323-9
39156-41-7
Carc. 1B; Muta. 2; Acute Tox. 4
206-348-1
329-71-5
Acute Tox. 3; STOT RE 2
440-030-5
338735-71-0
Skin Irrit. 2; Eye Dam. 1
253-037-1
36437-37-3
yes
XU 40304.03L ANTIMICROBIAL
405-640-8
36362-09-1
STOT RE 2; Skin Irrit. 2; Eye Dam. 1
AMINOETHER
412-310-7
37866-45-8
Skin Sens. 1
222-598-4
3547-33-9
Eye Dam. 1
223-346-6
3846-71-7
yes
EF-40
406-110-9
35950-52-8
Acute Tox. 4; STOT RE 2; Skin Corr. 1B; Skin Sens. 1
433-360-6
34036-80-1
STOT RE 2; Skin Sens. 1
221-499-3
3121-61-7
Flam. Liq. 3; Muta. 2; Repr. 1B; Acute Tox. 3; Acute Tox. 4; Skin Corr. 1C; Eye Dam. 1; Skin Sens. 1
252-343-2
35073-27-9
Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
SALICYNALVA
423-460-8
3508-98-3
Acute Tox. 4
223-228-4
3775-90-4
Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
442-230-8
321679-52-1
Eye Dam. 1
440-770-9
371921-63-0
Eye Dam. 1
439-500-2
33831-83-3
Acute Tox. 4; Skin Irrit. 2
5-(3-PYRIDYL)-TETRAZOL
426-810-8
3250-74-6
Eye Dam. 1
3-(DIMETHYLAMINO)PROPYL UREA; HST 2844
401-950-2
31506-43-1
Eye Dam. 1
3-CHLORO-2,4-DIFLUORONITROBENZENE
411-980-8
3847-58-3
Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
CC14837; SKF 106224
414-990-0
302-97-6
Repr. 2
250-863-4
31906-04-4
Skin Sens. 1A
FAP
402-230-0
399-95-1
Carc. 1B; Acute Tox. 4; Skin Sens. 1
221-627-8
3165-93-3
Carc. 1B; Muta. 2; Acute Tox. 3
251-684-4
33813-20-6
Acute Tox. 4
IMEXINE OAY
412-130-9
3131-52-0
Acute Tox. 4; Eye Dam. 1
ATIPACL
417-220-1
37441-29-5
Skin Sens. 1
429-290-0
3380-30-1
Eye Dam. 1
A-87440.0; A-87440.00
414-780-9
38585-74-9
Eye Dam. 1
BPFL; FLUOREN-BIS-PHENOL
406-950-6
3236-71-3
Eye Irrit. 2; Skin Irrit. 2
250-241-2
30560-19-1
Acute Tox. 4
251-899-3
34256-82-1
Carc. 2; Repr. 2; Acute Tox. 4; STOT SE 3; STOT RE 2; Skin Irrit. 2; Skin Sens. 1
206-121-7
302-27-2
Acute Tox. 2
206-215-8
309-00-2
Carc. 2; Acute Tox. 3; STOT RE 1
672-776-4
348635-87-0
Carc. 2; Eye Irrit. 2
251-375-4
33089-61-1
Acute Tox. 4; STOT RE 2; Skin Sens. 1
221-470-5
3108-42-7
Carc. 2; Repr. 1B; Lact.
yes
223-320-4
3825-26-1
Carc. 2; Repr. 1B; Lact.; Acute Tox. 4; STOT RE 1; Eye Dam. 1
yes
223-297-0
3813-05-6
Eye Irrit. 2; Skin Irrit. 2
250-859-2
31895-22-4
Acute Tox. 4
221-201-1
3030-47-5
Acute Tox. 3; Acute Tox. 4; Skin Corr. 1B
608-595-4
312600-89-8
Flam. Sol. 1; Acute Tox. 4; STOT RE 2; Eye Dam. 1
TITANCHELAT ETAM
410-500-4
357921-97-2
Eye Dam. 1
206-614-7
357-57-3
Acute Tox. 2
-
34492-97-2
Carc. 1A; STOT RE 1; Skin Sens. 1
252-139-3
34681-10-2
Flam. Liq. 3; Acute Tox. 3; Eye Irrit. 2
253-465-9
37329-65-0
Resp. Sens. 1
206-117-5
302-17-0
Acute Tox. 3; Eye Irrit. 2; Skin Irrit. 2

Export search results to: