EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1

Active Implantable Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007

This list contains hazardous substances for purposes of Directive 90/385/EEC on active implantable medical devices, particularly as regards Article 3 and Annex I (Essential Requirements). This non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Please note that Regulation (EU) 2017/745 on medical devices has repealed Directive 90/385/EEC and begun to apply from 26 May 2021. Nevertheless, Article 120 of the Regulation provides for a transitional period allowing medical devices, under specified conditions (e.g., placed on the market prior to 26 May 2021), to continue to comply with the Directive. In accordance with the fourth paragraph of Article 120, this period ends 26 May 2025.

Last updated 20 May 2024. Database contains 4753 unique substances/entries.
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250-339-5
30784-30-6
yes
231-956-9
7782-44-7
Ox. Gas 1; Press. Gas
219-679-1
2497-07-6
Acute Tox. 2; Acute Tox. 3
211-745-8
693-21-0
Unst. Expl.; Acute Tox. 2; Acute Tox. 1; STOT RE 2
211-745-8
693-21-0
Expl. 1.1; Acute Tox. 2; Acute Tox. 1; STOT RE 2
203-430-9
106-75-2
Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
206-110-7
301-12-2
Acute Tox. 3
226-066-2
5259-88-1
Acute Tox. 4
LUCHEM HA-R 100; LUPERSOL HA-R 100
413-230-5
122035-71-6
Eye Dam. 1; Skin Sens. 1
DAISO CCS-1S-E; S-GLYTO
417-210-7
70987-78-9
Carc. 1B; Muta. 2; Eye Dam. 1; Skin Sens. 1
271-846-8
68609-97-2
Skin Irrit. 2; Skin Sens. 1
604-430-5
144651-06-9
STOT RE 2
245-445-3
23135-22-0
Acute Tox. 2; Acute Tox. 4
207-306-5
460-19-5
Press. Gas; Flam. Gas 1; Acute Tox. 3
243-867-2
20543-06-0
Carc. 1A; STOT RE 1; Skin Sens. 1
202-464-1
95-92-1
Acute Tox. 4; Eye Irrit. 2
205-634-3
144-62-7
Acute Tox. 4
254-637-6
39807-15-3
Repr. 2; STOT RE 2
211-139-3
630-60-4
Acute Tox. 3; STOT RE 2
244-058-7
20816-12-0
Acute Tox. 2; Acute Tox. 1; Skin Corr. 1B
237-560-2
13840-56-7
Repr. 1B
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Phenylmercury dimethyldithiocarbamate EC / List no: 251-026-6 | CAS no: 32407-99-1
Mercury, chloro(4-((2,4-dinitrophenyl)amino)phenyl)- EC / List no: - | CAS no: 15785-93-0
(acetato-O)[3-(chloromethoxy)propyl-C,O]mercury EC / List no: 227-719-4 | CAS no: 5954-14-3
Chloromethylmercury EC / List no: 204-064-2 | CAS no: 115-09-3
4-(Chloromercuri)benzenesulfonic acid monosodium salt EC / List no: 683-356-5 | CAS no: 14110-97-5
2-ethoxyethylmercury acetate EC / List no: 204-678-0 | CAS no: 124-08-3
Lactic acid, mercury(2+) salt (2:1) (8CI) EC / List no: - | CAS no: 814-82-4
Phenyl(quinolin-8-olato-N1,O8)mercury EC / List no: 238-316-8 | CAS no: 14354-56-4
Bis(ethylthio)mercury EC / List no: - | CAS no: 811-50-7
Mersalyl acid EC / List no: 207-637-5 | CAS no: 486-67-9
[μ-[orthoborato(2-)-O:O']]diphenyldimercury EC / List no: 228-465-7 | CAS no: 6273-99-0
Di(acetato-O)anilinemercury EC / List no: 264-306-8 | CAS no: 63549-47-3
Bis(5-oxo-DL-prolinato-N1,O2)mercury EC / List no: 304-523-8 | CAS no: 94276-38-7
(acetato-O)methylmercury EC / List no: 203-547-5 | CAS no: 108-07-6
(neodecanoato-O)phenylmercury EC / List no: 247-783-7 | CAS no: 26545-49-3
[μ-[metasilicato(2-)-O:O]]bis(2-methoxyethyl)dimercury EC / List no: 242-997-7 | CAS no: 19367-79-4
Mersalyl EC / List no: 207-748-9 | CAS no: 492-18-2
Methyl(pentachlorophenolato)mercury EC / List no: 227-596-7 | CAS no: 5902-76-1
(2-ethylhexanoato)phenylmercury EC / List no: 236-326-7 | CAS no: 13302-00-6
Phenylmercury nitrate EC / List no: 200-242-9 | CAS no: 55-68-5
Di-sec-butylmercury EC / List no: - | CAS no: 691-88-3
Dimethyl[μ-[sulphato(2-)-O:O']]dimercury EC / List no: 223-288-1 | CAS no: 3810-81-9
Mercury di(acetate) EC / List no: 216-491-1 | CAS no: 1600-27-7
Mercaptomerin sodium EC / List no: 244-298-2 | CAS no: 21259-76-7
Mercury, chloropyridinyl- EC / List no: - | CAS no: 1334-75-4
Mercury, bis(3-fluorophenyl)- EC / List no: - | CAS no: 1961-02-0
3-(Acetoxymercuri)pyridine EC / List no: - | CAS no: 102-99-8
2-methoxyethylmercury chloride EC / List no: 204-659-7 | CAS no: 123-88-6
Hydrargaphen EC / List no: 238-107-1 | CAS no: 14235-86-0
6-methyl-3-nitrobenzoxamercurete EC / List no: 205-112-5 | CAS no: 133-58-4
[salicylato(2-)-O1,O2]mercury EC / List no: 227-760-8 | CAS no: 5970-32-1
Sodium 4-chloromercuriobenzoate EC / List no: 221-700-4 | CAS no: 3198-04-7
Mercury bis(4-chlorobenzoate) EC / List no: 239-548-2 | CAS no: 15516-76-4
p-tolylmercury chloride EC / List no: 208-716-7 | CAS no: 539-43-5
Mercuderamide EC / List no: 208-371-2 | CAS no: 525-30-4
Mercury hydrogen cyclohexanebutyrate EC / List no: 263-665-8 | CAS no: 62638-02-2
(3-chloro-4-hydroxyphenyl)mercury;hydrate EC / List no: - | CAS no: 538-04-5
(2-carboxy-m-tolyl)hydroxymercury, monosodium salt EC / List no: 258-195-5 | CAS no: 52795-88-7
Mercury dioleate EC / List no: 214-741-4 | CAS no: 1191-80-6
[μ-[(oxydiethylene phthalato)(2-)]]diphenylmercury EC / List no: 301-792-3 | CAS no: 94070-93-6
(4-((4-(Dimethylamino)phenyl)azo)phenyl)mercuric acetate EC / List no: 631-561-5 | CAS no: 19447-62-2
Mercury distearate EC / List no: 211-458-8 | CAS no: 645-99-8
Mercury bis(2-ethylhexanoate) EC / List no: 236-113-9 | CAS no: 13170-76-8
Sodium timerfonate EC / List no: 227-741-4 | CAS no: 5964-24-9
[(2-hydroxyethyl)amino]phenylmercury acetate EC / List no: 263-211-9 | CAS no: 61792-06-1
Diisopropylmercury EC / List no: - | CAS no: 1071-39-2
Phenyl(tribromomethyl)mercury EC / List no: 221-963-5 | CAS no: 3294-60-8
Hydrogen [metasilicato(2-)-O](2-methoxyethyl)mercurate(1-) EC / List no: 264-920-6 | CAS no: 64491-92-5
4-Chloromercuriphenol EC / List no: - | CAS no: 623-07-4
Amminephenylmercury(1+) acetate EC / List no: 245-006-6 | CAS no: 22450-90-4
(Trifluoromethyl)mercuric bromide EC / List no: - | CAS no: 421-09-0
basic phenylmercury nitrate EC / List no: 620-403-0 | CAS no: 8003-05-2
Phenylmercury acetate EC / List no: 200-532-5 | CAS no: 62-38-4
Iodomethylmercury EC / List no: 205-600-8 | CAS no: 143-36-2
Chloro-o-tolylmercury EC / List no: 220-469-7 | CAS no: 2777-37-9
Phenylmercury benzoate EC / List no: 202-331-8 | CAS no: 94-43-9
Hydrogen μ-hydroxy[μ-[orthoborato(3-)-O:O']]diphenyldimercurate(1-) EC / List no: 304-637-8 | CAS no: 94277-53-9
Chloromercuriferrocene EC / List no: 631-381-7 | CAS no: 1273-75-2
Chlormerodrin EC / List no: 200-530-4 | CAS no: 62-37-3
Mercurate(2-), tetraiodo-, copper(2+) (1:1), (T-4)- EC / List no: - | CAS no: 27228-67-7
2-chloromercuriophenol EC / List no: 201-962-6 | CAS no: 90-03-9
(maleoyldioxy)bis[phenylmercury] EC / List no: 220-286-2 | CAS no: 2701-61-3
(acetato-O)ethylmercury EC / List no: 203-688-2 | CAS no: 109-62-6
mercury, chloro(3-hydroxyphenyl)- EC / List no: - | CAS no: 70538-27-1
Phenylmercury stearate EC / List no: 203-217-0 | CAS no: 104-59-6
Merbromin EC / List no: 204-933-6 | CAS no: 129-16-8
Phenylmercury propionate EC / List no: 203-094-3 | CAS no: 103-27-5
Mercury, (acetato-O)(methylphenyl)- EC / List no: - | CAS no: 1300-78-3
Methylmercury hydroxide EC / List no: 214-667-2 | CAS no: 1184-57-2
Amylmercury chloride EC / List no: - | CAS no: 544-15-0
Disodium tetra(cyano-C)mercurate(2-) EC / List no: 239-766-8 | CAS no: 15682-88-9
4-hydroxymercuric?phenyl sulfonic acid, sodium salt EC / List no: - | CAS no: 73548-15-9
Diphenylmercury EC / List no: 209-606-1 | CAS no: 587-85-9
2-(ethylmercuriothio)benzoic acid EC / List no: 205-719-5 | CAS no: 148-61-8
Bromo(2-hydroxypropyl)mercury EC / List no: 242-613-8 | CAS no: 18832-83-2
Octadecanoic acid, mercury(1+) salt EC / List no: - | CAS no: 86320-46-9
Bis[(trimethylsilyl)methyl]mercury EC / List no: 236-315-7 | CAS no: 13294-23-0
Mercury, diheptyl- EC / List no: - | CAS no: 51622-02-7
(lactato-O1,O2)mercury EC / List no: 242-673-5 | CAS no: 18918-06-4
(2,3,4,5,6-pentachlorophenoxy)-phenylmercury EC / List no: - | CAS no: 1142-64-9
Meralein sodium EC / List no: 224-498-6 | CAS no: 4386-35-0
[naphthoato(1-)-O]phenylmercury EC / List no: 250-736-3 | CAS no: 31632-68-5
Dipropyl mercury EC / List no: - | CAS no: 628-85-3
Mercury succinate EC / List no: 209-656-4 | CAS no: 589-65-1
Thiomersal EC / List no: 200-210-4 | CAS no: 54-64-8
Bromomethylmercury EC / List no: 208-057-5 | CAS no: 506-83-2
(oleato)phenylmercury EC / List no: 203-218-6 | CAS no: 104-60-9
Mercury(2+) chloroacetate EC / List no: 247-925-8 | CAS no: 26719-07-3
Mercury, (nitrate-O)(trifluoromethyl)- EC / List no: - | CAS no: 461-40-5
Trimercury biscitrate EC / List no: 242-096-9 | CAS no: 18211-85-3
2-Acetoxymercurio-4-nitrophenol EC / List no: - | CAS no: 63468-53-1
2-Chloromercuri-4-nitrophenol EC / List no: - | CAS no: 24579-90-6
Mercurous gluconate EC / List no: - | CAS no: 63937-14-4
2-methoxyethylmercury acetate EC / List no: 205-790-2 | CAS no: 151-38-2
Dibutylrtut EC / List no: - | CAS no: 629-35-6
4-Chloromercuribenzenesulfonate EC / List no: - | CAS no: 554-77-8
Diethylmercury EC / List no: 211-000-7 | CAS no: 627-44-1
Phenylmercuric phthalate EC / List no: 664-337-0 | CAS no: 84-70-8
Phenylmercury chloride EC / List no: 202-865-1 | CAS no: 100-56-1
Mercury(1+) trifluoroacetate EC / List no: 220-875-4 | CAS no: 2923-15-1
Mercury, (acetato)pyridyl- (8CI) EC / List no: - | CAS no: 1334-77-6
Bromophenylmercury EC / List no: 214-760-8 | CAS no: 1192-89-8
Mercury(2+) tetrakis(thiocyanato-N)cobaltate(2-) EC / List no: 248-602-4 | CAS no: 27685-51-4
Diiodo(5-iodopyridin-2-amine-N1)mercury EC / List no: 298-602-3 | CAS no: 93820-20-3
Mercury dithizonate EC / List no: 621-496-0 | CAS no: 14783-59-6
(dihydroxyphenyl)phenylmercury EC / List no: 248-426-8 | CAS no: 27360-58-3
[benzoato(2-)-C2,O1]mercury EC / List no: 227-228-5 | CAS no: 5722-59-8
Dimercury di(acetate) EC / List no: 211-161-3 | CAS no: 631-60-7
Ethylmercury chloride EC / List no: 203-478-0 | CAS no: 107-27-7
Mercury difulminate EC / List no: 211-057-8 | CAS no: 628-86-4
4-aminophenylmercury acetate EC / List no: 228-497-1 | CAS no: 6283-24-5
Chloro-m-tolylmercury EC / List no: 227-722-0 | CAS no: 5955-19-1
Diiodobis(5-iodopyridin-2-amine)mercury dihydroiodide EC / List no: 264-100-8 | CAS no: 63325-16-6
2-hydroxy-5-(1,1,3,3-tetramethylbutyl)phenylmercury acetate EC / List no: 209-534-0 | CAS no: 584-18-9
Naphthenic acids, mercury salts EC / List no: 215-651-8 | CAS no: 1336-96-5
Chloro(hydroxyphenyl)mercury EC / List no: 215-308-2 | CAS no: 1320-80-5
Otimerate sodium EC / List no: 240-572-0 | CAS no: 16509-11-8
Methylmercury benzoate EC / List no: 222-834-6 | CAS no: 3626-13-9
Ethylhydroxymercury EC / List no: - | CAS no: 107-28-8
Bis[(+)-lactato]mercury EC / List no: 251-657-7 | CAS no: 33724-17-3
Diphenyl[μ-[(tetrapropenyl)succinato(2-)-O:O']]dimercury EC / List no: 248-355-2 | CAS no: 27236-65-3
[2,2',2''-nitrilotri(ethanol)-N,O,O',O'']phenylmercury lactate EC / List no: 245-581-3 | CAS no: 23319-66-6
methylmercury nitrile EC / List no: - | CAS no: 2597-97-9
Mercury(2+) (9Z,12Z)-octadeca-9,12-dienoate EC / List no: 231-814-6 | CAS no: 7756-49-2
Chloropropylmercury EC / List no: - | CAS no: 2440-40-6
Mercury(1+) ethyl sulphate EC / List no: 275-904-3 | CAS no: 71720-55-3
Phenyl(trichloromethyl)mercury EC / List no: 221-960-9 | CAS no: 3294-57-3
Mercury, iodo(trifluoromethyl)- EC / List no: - | CAS no: 421-11-4
Mercurobutol EC / List no: 207-869-7 | CAS no: 498-73-7
1-cyano-3-(methylmercurio)guanidine EC / List no: 207-935-5 | CAS no: 502-39-6
Di-o-tolylmercury EC / List no: 210-499-9 | CAS no: 616-99-9
Phenylmercury hydroxide EC / List no: 202-866-7 | CAS no: 100-57-2
(metaborato-O)phenylmercury EC / List no: 250-518-8 | CAS no: 31224-71-2
Bis(ethylmercuri)phosphate EC / List no: - | CAS no: 2440-45-1
Chloro(trans-2-methoxycyclooctyl)mercury EC / List no: - | CAS no: 5185-84-2
Hydroxymercury nitrile EC / List no: - | CAS no: 31065-88-0
Di-p-tolylmercury EC / List no: 208-672-9 | CAS no: 537-64-4
1H-Tetrazole, 5-nitro-, mercury(2+) salt EC / List no: - | CAS no: 60345-95-1
Chloro-2-thienylmercury EC / List no: 227-481-1 | CAS no: 5857-39-6
(Pentafluorophenyl)mercury EC / List no: - | CAS no: 973-17-1
Phenylmercury salicylate EC / List no: 248-828-3 | CAS no: 28086-13-7
Chloro[p-[(2-hydroxy-1-naphthyl)azo]phenyl]mercury EC / List no: 221-358-6 | CAS no: 3076-91-3
Mercury, bis(phenylmethyl)- EC / List no: 677-698-4 | CAS no: 780-24-5
Bis(5-oxo-L-prolinato-N1,O2)mercury EC / List no: 305-388-8 | CAS no: 94481-62-6
Ethyliodomercury EC / List no: 219-471-0 | CAS no: 2440-42-8
Dihydrogen [orthoborato(3-)-O]phenylmercurate(2-) EC / List no: 203-068-1 | CAS no: 102-98-7
Di(phenylmercury) dodecylsuccinate EC / List no: - | CAS no: 24806-32-4
[μ-[(oxydiethylene but-2-enedioato)(2-)]]diphenyldimercury EC / List no: 301-791-8 | CAS no: 94070-92-5
N-(ethylmercurio)toluene-4-sulphonanilide EC / List no: 208-231-0 | CAS no: 517-16-8
Disuccinimidomercury EC / List no: 209-537-7 | CAS no: 584-43-0
Sodium 4-hydroxymercuriobenzoate EC / List no: 205-340-5 | CAS no: 138-85-2
Mercury bis(trifluoroacetate) EC / List no: 236-250-4 | CAS no: 13257-51-7
Bis(lactato-O1,O2)mercury EC / List no: 242-667-2 | CAS no: 18917-83-4
Bis(trichloromethyl)mercury EC / List no: 229-867-5 | CAS no: 6795-81-9
BMC EC / List no: 663-974-1 | CAS no: 543-63-5
Iodo(iodomethyl)mercury EC / List no: 205-485-4 | CAS no: 141-51-5
Mercury, hydroxy(hydroxynitrophenyl)-, monosodium salt EC / List no: - | CAS no: 1300-34-1
Mercury, iodophenyl- EC / List no: 664-429-0 | CAS no: 823-04-1
4-chloromercuriobenzoic acid EC / List no: 200-442-6 | CAS no: 59-85-8
Mercury acetate EC / List no: 209-766-2 | CAS no: 592-63-2
Mercury dibenzoate EC / List no: 209-499-1 | CAS no: 583-15-3
methylmercury salts EC / List no: 694-823-8 | CAS no: 22967-92-6
(phenylmercurio)urea EC / List no: 218-909-8 | CAS no: 2279-64-3
Lactatophenylmercury EC / List no: 204-560-9 | CAS no: 122-64-5
Tris(ethylmercury) phosphate EC / List no: 218-790-2 | CAS no: 2235-25-8
Dipotassium tetracyanomercurate EC / List no: 209-735-3 | CAS no: 591-89-9
2-ethoxyethylmercury chloride EC / List no: 204-670-7 | CAS no: 124-01-6
(acetato-O)diamminephenylmercury EC / List no: 269-247-1 | CAS no: 68201-97-8
(bromodichloromethyl)phenylmercury EC / List no: 221-961-4 | CAS no: 3294-58-4
Ethanethiolmercury chloride EC / List no: - | CAS no: 1785-43-9
Bromoethylmercury EC / List no: 203-477-5 | CAS no: 107-26-6
[2-ethylhexyl hydrogen maleato-O']phenylmercury EC / List no: 248-559-1 | CAS no: 27605-30-7
(2-carboxyphenyl)hydroxymercury EC / List no: 237-918-8 | CAS no: 14066-61-6
Mercurate(1-), [dodecenylbutanedioato(2-)-O']phenyl-, hydrogen EC / List no: 304-575-1 | CAS no: 94276-88-7
-
-
Acute Tox. 2; Acute Tox. 1; STOT RE 2
215-235-6
1314-41-6
yes
214-197-8
1113-02-6
Acute Tox. 3; Acute Tox. 4
An inorganic pigment that is the reaction product of high temperature calcination in which nickel (II) oxide and silicon oxide in varying amounts are homogeneously and ionically interdiffused to form a crystalline matrix of olivine. Its composition may include any one or a combination of the modifiers alkali or alkaline earth halides.
271-112-7
68515-84-4
Carc. 1A; STOT RE 1; Skin Sens. 1
-
-
yes
-
-
Skin Corr. 1A; STOT SE 3
213-853-0
1034-01-1
Acute Tox. 4; Skin Sens. 1
247-761-7
26530-20-1
Acute Tox. 2; Acute Tox. 3; Skin Corr. 1; Eye Dam. 1; Skin Sens. 1A
H112339
413-550-5
-
Skin Irrit. 2; Eye Dam. 1
PROCION BRILLIANT ORANGE H-EXL; S156745
412-960-1
148878-21-1
Eye Dam. 1; Skin Sens. 1
204-677-5
124-07-2
Skin Corr. 1C
203-892-1
111-65-9
Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
209-136-7
556-67-2
Repr. 2
yes
204-695-3
124-30-1
Asp. Tox. 1; STOT RE 2; Skin Irrit. 2; Eye Dam. 1
202-422-2
95-47-6
Flam. Liq. 3; Acute Tox. 4; Skin Irrit. 2
202-429-0
95-53-4
Carc. 1B; Acute Tox. 3; Eye Irrit. 2
yes
show/hide
N,N'-(3,3'-dimethylbiphenyl-4,4'-ylene)di(acetoacetamide) EC / List no: 202-111-1 | CAS no: 91-96-3
-
-
Carc. 1B
210-418-7
615-28-1
Carc. 2; Muta. 2; Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
202-430-6
95-54-5
Carc. 2; Muta. 2; Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
201-855-4
88-74-4
Acute Tox. 3; STOT RE 2
434-350-4
103122-66-3
Flam. Liq. 3; Carc. 1B; Muta. 1B; Acute Tox. 4; STOT RE 2; Skin Sens. 1
432-750-3
109202-58-6
Carc. 1B; Muta. 1B; Acute Tox. 4; STOT RE 2; Skin Sens. 1
ETA; ETA 50 (50 %IGE ZUBEREITUNG); O-ETHYLHYDROXYLAMINE
402-030-3
624-86-2
Flam. Liq. 2; Acute Tox. 3; STOT RE 1; Eye Irrit. 2; Skin Sens. 1
218-276-8
2104-64-5
Acute Tox. 1; Acute Tox. 2
show/hide
N,N'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[3-oxobutyramide] EC / List no: 223-873-1 | CAS no: 4104-12-5
-
-
Carc. 1B
202-423-8
95-48-7
Acute Tox. 3; Skin Corr. 1B
227-534-9
5873-54-1
Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
221-817-0
3244-90-4
Acute Tox. 4
KENODOX
404-300-6
116753-76-5
Org. Perox. C

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