EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1

Active Implantable Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007

This list contains hazardous substances for purposes of Directive 90/385/EEC on active implantable medical devices, particularly as regards Article 3 and Annex I (Essential Requirements). This non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Please note that Regulation (EU) 2017/745 on medical devices has repealed Directive 90/385/EEC and begun to apply from 26 May 2021. Nevertheless, Article 120 of the Regulation provides for a transitional period allowing medical devices, under specified conditions (e.g., placed on the market prior to 26 May 2021), to continue to comply with the Directive. In accordance with the fourth paragraph of Article 120, this period ends 26 May 2025.

Last updated 24 April 2024. Database contains 4753 unique substances/entries.

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Showing 1,751 - 1,800 of 4,753 results.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU REACH: List of SVHC
bisphenol A; 4,4'-isopropylidenediphenol	201-245-8	80-05-7	Repr. 1B; STOT SE 3; Eye Dam. 1; Skin Sens. 1	yes
Borate(2-), tetrahydroxybis[μ-(peroxy-κO1:κO2)]di-, sodium (1:2)	-	90568-23-3		yes
Borate(2-), tetrahydroxybis[μ-(peroxy-κO1:κO2)]di-, sodium, hydrate (1:2:6)	-	125022-34-6		yes
bordeaux mixture; reaction products of copper sulphate with calcium dihydroxide	616-932-1	8011-63-0	Acute Tox. 4; Eye Dam. 1
boric acid	233-139-2	10043-35-3	Repr. 1B	yes
boric acid	234-343-4	11113-50-1	Repr. 1B	yes
boron tribromide	233-657-9	10294-33-4	Acute Tox. 2; Skin Corr. 1A
boron trichloride	233-658-4	10294-34-5	Press. Gas; Acute Tox. 2; Skin Corr. 1B
boron trifluoride	231-569-5	7637-07-2	Press. Gas; Acute Tox. 2; Skin Corr. 1A
bromadiolone (ISO); 3-[3-(4'-bromobiphenyl-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2H-chromen-2-one	249-205-9	28772-56-7	Repr. 1B; Acute Tox. 1; STOT RE 1
bromelain, juice	232-572-4	9001-00-7	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
bromine	231-778-1	7726-95-6	Acute Tox. 2; Skin Corr. 1A
bromoacetic acid	201-175-8	79-08-3	Acute Tox. 3; Skin Corr. 1A; Skin Sens. 1
bromobenzene	203-623-8	108-86-1	Flam. Liq. 3; Skin Irrit. 2
bromobenzylbromotoluene, reaction mass of isomers DBBT	402-210-1	99688-47-8	STOT RE 2; Skin Sens. 1
bromoethane; ethyl bromide	200-825-8	74-96-4	Flam. Liq. 2; Carc. 2; Acute Tox. 4
bromoethylene	209-800-6	593-60-2	Press. Gas; Flam. Gas 1; Carc. 1B
bromofenoxim (ISO); 3,5-dibromo-4-hydroxybenzaldehyde-O-(2,4-dinitrophenyl)-oxime	236-129-6	13181-17-4	Acute Tox. 4
bromoform; tribromomethane	200-854-6	75-25-2	Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
bromomethane; methylbromide	200-813-2	74-83-9	Press. Gas; Muta. 2; Acute Tox. 3; STOT RE 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
bromophos (ISO); O-4-bromo-2,5-dichlorophenyl O,O-dimethyl phosphorothioate	218-277-3	2104-96-3	Acute Tox. 4
bromophos-ethyl (ISO); O-4-bromo-2,5-dichlorophenyl; O,O-diethyl phosphorothioate	225-399-0	4824-78-6	Acute Tox. 3; Acute Tox. 4
bromoxynil (ISO) 3,5-dibromo-4-hydroxybenzonitrile; bromoxynil phenol show/hide 3,5-dibromo-4-hydroxybenzonitrile EC / List no: 216-882-7 \| CAS no: 1689-84-5 2,6-dibromo-4-cyanophenyl octanoate EC / List no: 216-885-3 \| CAS no: 1689-99-2 2,6-dibromo-4-cyanophenyl heptanoate EC / List no: 260-300-4 \| CAS no: 56634-95-8 2,6-dibromo-4-cyanophenyl butyrate EC / List no: 223-374-9 \| CAS no: 3861-41-4	216-882-7	1689-84-5	Repr. 2; Acute Tox. 2; Acute Tox. 3; Skin Sens. 1
bromoxynil heptanoate (ISO); 2,6-dibromo-4-cyanophenyl heptanoate	260-300-4	56634-95-8	Repr. 2; Acute Tox. 4; Skin Sens. 1
bromoxynil octanoate (ISO); 2,6-dibromo-4-cyanophenyl octanoate	216-885-3	1689-99-2	Repr. 2; Acute Tox. 3; Acute Tox. 4; Skin Sens. 1
bronopol (INN); 2-bromo-2-nitropropane-1,3-diol	200-143-0	52-51-7	Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
brucine nitrate	227-317-9	5786-97-0	Acute Tox. 2
brucine sulphate	225-432-9	4845-99-2	Acute Tox. 2
brucine; 2,3-dimethoxystrychnine	206-614-7	357-57-3	Acute Tox. 2
bufa-4,20,22-trienolide, 6-(acetyloxy)-3-(β-D-glucopyranosyloxy)-8,14-dihydroxy-, (3β, 6β)-; red squill; scilliroside	208-077-4	507-60-8	Acute Tox. 2
bufencarb (ISO); reaction mass of 3-(1-methylbutyl)phenyl N-methylcarbamate and 3-(1-ethylpropyl)phenyl N-methylcarbamate	620-359-2	8065-36-9	Acute Tox. 3
bunsenite	-	34492-97-2	Carc. 1A; STOT RE 1; Skin Sens. 1
bupirimate (ISO); 5-butyl-2-ethylamino-6-methylpyrimidin-4-yl dimethylsulphamate	255-391-2	41483-43-6	Carc. 2; Skin Sens. 1B
but-1-ene	203-449-2	106-98-9	Flam. Gas 1; Press. Gas
but-2-yne-1,4-diol; 2-butyne-1,4-diol	203-788-6	110-65-6	Skin Corr. 1B; Acute Tox. 3; Acute Tox. 4; STOT RE 2; Skin Sens. 1
butan-1-ol; n-butanol	200-751-6	71-36-3	Flam. Liq. 3; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
butane;butane (containing ≥ 0,1 % butadiene (203-450-8))	203-448-7	106-97-8	Flam. Gas 1; Press. Gas; Carc. 1A; Muta. 1B
butane;butane (containing ≥ 0,1 % butadiene (203-450-8))	203-448-7	106-97-8	Flam. Gas 1; Press. Gas
butanone oxime; ethyl methyl ketoxime; ethyl methyl ketone oxime	202-496-6	96-29-7	Carc. 1B; Acute Tox. 4; Acute Tox. 3; STOT SE 3; STOT SE 1; STOT RE 2; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
butanone; ethyl methyl ketone	201-159-0	78-93-3	Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
butene, mixed-1-and-2-isomers	203-452-9	107-01-7	Flam. Gas 1; Press. Gas
butocarboxim (ISO); 3-(methylthio)-2-butanone O-[(methylamino)carbonyl]oxime	252-139-3	34681-10-2	Flam. Liq. 3; Acute Tox. 3; Eye Irrit. 2
butroxydim (ISO); 5-(3-butyryl-2,4,6-trimethylphenyl)-2-[1-(ethoxyimino)propyl]-3-hydroxycyclohex-2-en-1-one BUTROXYDIM; ICIA0500	414-790-3	138164-12-2	Repr. 2; Acute Tox. 4; Skin Irrit. 2
butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium (trialkyloxy)titanium phosphate TILCOM CA35; TILCOM IA10; TYTAN AP 100; TYTAN CA 100; TYTAN CX 35; TYZOR IAM	401-100-0	109037-78-7	Flam. Liq. 2; Eye Irrit. 2
Butyl 4-hydroxybenzoate	202-318-7	94-26-8		yes
butyl butyrate	203-656-8	109-21-7	Flam. Liq. 3
butyl chloroformate; chloroformic acid butyl ester	209-750-5	592-34-7	Flam. Liq. 3; Acute Tox. 3; Skin Corr. 1B
butyl formate	209-772-5	592-84-7	Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
butyl glycidyl ether; butyl 2,3-epoxypropyl ether	219-376-4	2426-08-6	Flam. Liq. 3; Carc. 2; Muta. 2; Acute Tox. 4; STOT SE 3; Skin Sens. 1
butyl nitrite	208-862-1	544-16-1	Flam. Liq. 2; Acute Tox. 3

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Active Implantable Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007

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Last updated 24 April 2024. Database contains 4753 unique substances/entries.

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