EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1

Active Implantable Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007

This list contains hazardous substances for purposes of Directive 90/385/EEC on active implantable medical devices, particularly as regards Article 3 and Annex I (Essential Requirements). This non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Please note that Regulation (EU) 2017/745 on medical devices has repealed Directive 90/385/EEC and begun to apply from 26 May 2021. Nevertheless, Article 120 of the Regulation provides for a transitional period allowing medical devices, under specified conditions (e.g., placed on the market prior to 26 May 2021), to continue to comply with the Directive. In accordance with the fourth paragraph of Article 120, this period ends 26 May 2025.

Last updated 23 April 2024. Database contains 4753 unique substances/entries.

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Showing 301 - 350 of 4,753 results.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)
dipotassium hexachloroplatinate	240-979-3	16921-30-5	Acute Tox. 3; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
disodium hexachloroplatinate	240-983-5	16923-58-3	Acute Tox. 3; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
hexachloroplatinates with the exception of those specified elsewhere in this Annex show/hide Dipotassium hexachloroplatinate EC / List no: 240-979-3 \| CAS no: 16921-30-5 Platinate(2-), hexachloro-, (OC-6-11)-, dihydrogen, reaction products with 2,4,6,8-tetraethenyl-2,4,6,8-tetramethylcyclotetrasiloxane EC / List no: 271-555-6 \| CAS no: 68585-32-0 Diammonium hexachloroplatinate EC / List no: 240-973-0 \| CAS no: 16919-58-7 Dicesium hexachloroplatinate EC / List no: 240-945-8 \| CAS no: 16902-25-3 Dihydrogen hexachloroplatinate, compound with 1,1,3,3-tetramethyl-1,3-divinyldisiloxane EC / List no: 258-092-5 \| CAS no: 52672-74-9 Bis(benzyltrimethylammonium) hexachloroplatinate(2-) EC / List no: 255-585-7 \| CAS no: 41909-89-1 Chloroplatinic acid hexahydrate EC / List no: 629-612-1 \| CAS no: 18497-13-7 Hexachloroplatinic acid EC / List no: 241-010-7 \| CAS no: 16941-12-1 Platinate(2-), hexachloro-, dihydrogen, (OC-6-11)-, reaction products with palladium EC / List no: - \| CAS no: 68516-04-1 Platinate(2-), hexachloro-, (OC-6-11)-, dihydrogen, reaction products with tributylphosphine hydrochloride and N-(3-(trimethoxysilyl)propyl)-1,2-ethanediamine EC / List no: - \| CAS no: 67924-25-8 Natriumchloroplatinat EC / List no: 626-326-9 \| CAS no: 19583-77-8 Hexachloroplatinate(2-) EC / List no: - \| CAS no: 16871-54-8 Disodium hexachloroplatinate EC / List no: 240-983-5 \| CAS no: 16923-58-3	-	-	Acute Tox. 3; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
tetrachloroplatinates with the exception of those specified elsewhere in this Annex show/hide Platinate(2-), tetrachloro-, dihydrogen, (SP-4-1) EC / List no: - \| CAS no: 17083-70-4 Dirubidium tetrachloroplatinate EC / List no: 237-503-1 \| CAS no: 13820-56-9 Diammonium tetrachloroplatinate EC / List no: 237-499-1 \| CAS no: 13820-41-2 Dipotassium tetrachloroplatinate EC / List no: 233-050-9 \| CAS no: 10025-99-7 Tetraammineplatinum tetrachloroplatinate EC / List no: 237-501-0 \| CAS no: 13820-46-7 Diamminetetrachloroplatinum EC / List no: 240-930-6 \| CAS no: 16893-05-3 Disodium tetrachloroplatinate EC / List no: 233-051-4 \| CAS no: 10026-00-3	-	-	Acute Tox. 3; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
(S)-α-hydroxy-3-phenoxy-benzeneacetonitrile	441-070-6	61826-76-4	Acute Tox. 3; Eye Dam. 1; Skin Sens. 1
2,3,5,6-tetrahydro-2-methyl-2H-cyclopenta[d]-1,2-thiazol-3-one CIN 10096132; MTI	407-630-9	82633-79-2	Acute Tox. 3; Eye Dam. 1; Skin Sens. 1
2,4-dichloro-3-ethyl-6-nitrophenol 2,4-DICHLORO-3-ETHYL-6-NITROPHENOL	420-740-1	99817-36-4	Acute Tox. 3; Eye Dam. 1; Skin Sens. 1
3,4-dichloroaniline	202-448-4	95-76-1	Acute Tox. 3; Eye Dam. 1; Skin Sens. 1
(2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen-6-one, rotenone	201-501-9	83-79-4	Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
p-benzoquinone; quinone	203-405-2	106-51-4	Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
2,2,4-trimethylhexamethylene-1,6-di-isocyanate	241-001-8	16938-22-0	Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
2,4,4-trimethylhexamethylene-1,6-di-isocyanate	239-714-4	15646-96-5	Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate; isophorone di-isocyanate	223-861-6	4098-71-9	Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
4,4'-methylenedi(cyclohexyl isocyanate); dicyclohexylmethane-4,4'-di-isocyanate	225-863-2	5124-30-1	Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
hexamethylene-di-isocyanate	212-485-8	822-06-0	Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
2,3,4,6-tetrachlorophenol	200-402-8	58-90-2	Acute Tox. 3; Eye Irrit. 2; Skin Irrit. 2
chloral hydrate; 2,2,2-trichloroethane-1,1-diol	206-117-5	302-17-0	Acute Tox. 3; Eye Irrit. 2; Skin Irrit. 2
sodium fluoride	231-667-8	7681-49-4	Acute Tox. 3; Eye Irrit. 2; Skin Irrit. 2
2,2'-oxydiethyl diacrylate; diethylene glycol diacrylate	223-791-6	4074-88-8	Acute Tox. 3; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
2,2-dimethyltrimethylene diacrylate; neopentyl glycol diacrylate	218-741-5	2223-82-7	Acute Tox. 3; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
benzene-1,4-diamine dihydrochloride; p-phenylenediamine dihydrochloride	210-834-9	624-18-0	Acute Tox. 3; Eye Irrit. 2; Skin Sens. 1
N5,N5-diethyltoluene-2,5-diamine monohydrochloride; 4-diethylamino-2-methylaniline monohydrochloride	218-130-3	2051-79-8	Acute Tox. 3; Eye Irrit. 2; Skin Sens. 1
p-phenylenediamine	203-404-7	106-50-3	Acute Tox. 3; Eye Irrit. 2; Skin Sens. 1
coumafuryl (ISO); fumarin; (RS)-3-(1-(2-furyl)-3-oxobutyl)4-hydroxycoumarin; 4-hydroxy-3-[3-oxo-1-(2-furyl)butyl]coumarin	204-195-5	117-52-2	Acute Tox. 3; STOT RE 1
fipronil (ISO); (±)-5-amino-1-(2,6-dichloro-α,α,α-trifluoro-para-tolyl)-4-trifluoromethylsulfinyl-pyrazole-3-carbonitrile	424-610-5	120068-37-3	Acute Tox. 3; STOT RE 1
pindone (ISO); 2-pivaloylindan-1,3-dione	201-462-8	83-26-1	Acute Tox. 3; STOT RE 1
sodium 4-(2,4,4-trimethylpentylcarbonyloxy)benzenesulfonate ACTIZONE; PG 85; PHENOLESTER C; PHENOLESTER C/S	400-030-8	94612-91-6	Acute Tox. 3; STOT RE 1; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Sens. 1
fluquinconazole (ISO);3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4-(3H)-one FLUQUINCONAZOLE	411-960-9	136426-54-5	Acute Tox. 3; STOT RE 1; Acute Tox. 4; Skin Irrit. 2
chloroacetyl chloride	201-171-6	79-04-9	Acute Tox. 3; STOT RE 1; Skin Corr. 1A
2-chloro-3-trifluoromethylpyridine	424-520-6	65753-47-1	Acute Tox. 3; STOT RE 1; Skin Corr. 1B
2-methoxyethylmercury chloride	204-659-7	123-88-6	Acute Tox. 3; STOT RE 1; Skin Corr. 1B
basic phenylmercury nitrate	620-403-0	8003-05-2	Acute Tox. 3; STOT RE 1; Skin Corr. 1B
phenylmercury acetate	200-532-5	62-38-4	Acute Tox. 3; STOT RE 1; Skin Corr. 1B
phenylmercury hydroxide	202-866-7	100-57-2	Acute Tox. 3; STOT RE 1; Skin Corr. 1B
phenylmercury nitrate	200-242-9	55-68-5	Acute Tox. 3; STOT RE 1; Skin Corr. 1B
ethyl 2-(3-benzoylphenyl)propanoate	414-920-9	60658-04-0	Acute Tox. 3; STOT RE 1; Skin Sens. 1
1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride DOXAZOSIN 4; DOXAZOSIN STEP 4	415-660-9	70918-74-0	Acute Tox. 3; STOT RE 2
2,3-dinitrophenol	200-628-7	66-56-8	Acute Tox. 3; STOT RE 2
2,4(or 2,6)-dinitrophenol	275-732-9	71629-74-8	Acute Tox. 3; STOT RE 2
2,5-dinitrophenol	206-348-1	329-71-5	Acute Tox. 3; STOT RE 2
2,6-dinitrophenol	209-357-9	573-56-8	Acute Tox. 3; STOT RE 2
2-ethoxyaniline; o-phenetidine	202-356-4	94-70-2	Acute Tox. 3; STOT RE 2
3,4-dinitrophenol	209-415-3	577-71-9	Acute Tox. 3; STOT RE 2
4-nitrotoluene	202-808-0	99-99-0	Acute Tox. 3; STOT RE 2
chloroanilines (with exception of those specified elsewhere in this Annex)	-	-	Acute Tox. 3; STOT RE 2
chlorodinitrobenzene	247-109-1	25567-67-3	Acute Tox. 3; STOT RE 2
digitoxin	200-760-5	71-63-6	Acute Tox. 3; STOT RE 2
dinitrophenol (reaction mass of isomers)	247-096-2	25550-58-7	Acute Tox. 3; STOT RE 2
diphenylamine	204-539-4	122-39-4	Acute Tox. 3; STOT RE 2
m-nitroaniline	202-729-1	99-09-2	Acute Tox. 3; STOT RE 2

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EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1

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Active Implantable Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007

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Last updated 23 April 2024. Database contains 4753 unique substances/entries.

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