EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1
EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1
Active Implantable Medical Devices Directive - Hazardous Substances
EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007
This list contains hazardous substances for purposes of Directive 90/385/EEC on active implantable medical devices, particularly as regards Article 3 and Annex I (Essential Requirements). This non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Please note that Regulation (EU) 2017/745 on medical devices has repealed Directive 90/385/EEC and begun to apply from 26 May 2021. Nevertheless, Article 120 of the Regulation provides for a transitional period allowing medical devices, under specified conditions (e.g., placed on the market prior to 26 May 2021), to continue to comply with the Directive. In accordance with the fourth paragraph of Article 120, this period ends 26 May 2025.
Last updated 22 September 2023. Database contains 4753 unique substances/entries.
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Benzenamine, 4,4'-carbonimidoylbis[N,N-dimethyl-, monohydrochloride, 2-hydroxyethanesulfonate
EC / List no:
-
| CAS no:
86157-51-9
Benzenesulfonic acid, 4-dodecyl-, compd. with 4,4'-carbonimidoylbis(N,N-dimethylbenzenamine) (1:1)
EC / List no:
-
| CAS no:
63589-43-5
4,4'-bis[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo][1,1'-biphenyl]-2,2'-disulphonic acid, compound with 4,4'-carbonimidoylbis[N,N-dimethylphenylamine] (1:2)
EC / List no:
277-106-0
| CAS no:
72939-51-6
Benzenamine, 4,4'-carbonimidoylbis[N,N-dimethyl-, monohydrochloride, (2-methoxyethoxy)acetate
EC / List no:
-
| CAS no:
82941-28-4
Decyl hydrogen sulphate, compound with 4,4'-carbonimidoylbis[N,N-dimethylaniline] (1:1)
EC / List no:
281-828-1
| CAS no:
84030-53-5
Benzenamine, 4,4'-carbonimidoylbis[N,N-dimethyl-, mono(dodecylbenzenesulfonate)
EC / List no:
-
| CAS no:
82794-01-2
4,4'-carbonimidoylbis(N,N-dimethylaniline) monohydrochloride
EC / List no:
219-567-2
| CAS no:
2465-27-2
Methanaminium, N-(4-(amino(4-(dimethylamino)phenyl)methylene)-2,5-cyclohexadien-1-ylidene)-N-methyl-, dodecyl(sulfophenoxy)benzenesulfonate (2:1)
EC / List no:
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| CAS no:
63428-09-1
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Carc. 2; Acute Tox. 4; Eye Irrit. 2 |
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265-294-7
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64969-36-4
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Carc. 1B; Acute Tox. 4 |
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277-985-0
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74753-18-7
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Carc. 1B; Acute Tox. 4 |
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210-322-5
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612-82-8
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Carc. 1B; Acute Tox. 4 |
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[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethoxy-, bis(2-hydroxy-3,5-dinitrobenzoate)
EC / List no:
-
| CAS no:
92415-49-1
[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethoxy-, bis(3,5-dinitrobenzoate)
EC / List no:
-
| CAS no:
92415-38-8
(1,1'-Biphenyl)-4,4'-diamine, 3,3'-dimethoxy-, monohydrochloride
EC / List no:
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| CAS no:
111984-09-9
[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethoxy-, mono(3,5-dinitrobenzoate)
EC / List no:
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| CAS no:
92415-53-7
[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethoxy-, mono(2-hydroxy-3,5-dinitrobenzoate)
EC / List no:
-
| CAS no:
92415-48-0
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Carc. 1B; Acute Tox. 4 |
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Carc. 1B; Acute Tox. 4; Skin Sens. 1 |
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210-313-6
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612-52-2
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Carc. 1A; Acute Tox. 4 |
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209-030-0
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553-00-4
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Carc. 1A; Acute Tox. 4 |
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Acute Tox. 4; Eye Dam. 1 |
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Tris(2-hydroxyethyl)ammonium (o,p-dichlorophenoxy)acetate
EC / List no:
219-911-1
| CAS no:
2569-01-9
Acetic acid, (2,4-dichlorophenoxy)-, compd. with 2-[2-[2-(octadecylamino)ethoxy]ethoxy]ethanol(1:1)
EC / List no:
-
| CAS no:
37937-04-5
1-[bis(2-hydroxypropyl)amino]propan-2-ol;2-(2,4-dichlorophenoxy)acetic acid
EC / List no:
639-766-1
| CAS no:
18584-79-7
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Acute Tox. 4; Eye Dam. 1; Skin Sens. 1 |
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yes |
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Carc. 1B; Acute Tox. 4 |
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Acute Tox. 4 |
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Acute Tox. 4 |
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Repr. 1B; Acute Tox. 2; Acute Tox. 3 |
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2-sec-butyl-4,6-dinitrophenol, compound with 2,2',2''-nitrilotriethanol (1:1)
EC / List no:
229-166-4
| CAS no:
6420-47-9
2-sec-butyl-4,6-dinitrophenol, compound with 2,2'-iminodiethanol (1:1)
EC / List no:
258-532-6
| CAS no:
53404-43-6
2-sec-butyl-4,6-dinitrophenol, compound with 1-aminopropan-2-ol (1:1)
EC / List no:
275-931-0
| CAS no:
71735-19-8
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Repr. 1B; Acute Tox. 3; Eye Irrit. 2 |
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Acute Tox. 3 |
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Acute Tox. 3 |
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Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2 |
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425-210-3
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169939-84-8
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Skin Sens. 1 |
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200-712-3
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69-72-7
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Repr. 2; Acute Tox. 4; Eye Dam. 1 |
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202-345-4
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94-59-7
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Carc. 1B; Muta. 2; Acute Tox. 4 |
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617-100-0
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8051-02-3
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Eye Irrit. 2; STOT SE 3; Skin Irrit. 2 |
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618-004-1
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87392-12-9
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Skin Sens. 1 |
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243-193-9
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19622-19-6
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Acute Tox. 4 |
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249-013-5
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28434-00-6
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Acute Tox. 4 |
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2635-50-9
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Acute Tox. 3 |
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2703-37-9
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Acute Tox. 2; Acute Tox. 1 |
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953-17-3
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Acute Tox. 3 |
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ALKYL ISOCYANATE SILANE SCD 617
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402-290-8
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85702-90-5
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Flam. Liq. 3; Resp. Sens. 1; Skin Sens. 1 |
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436-690-9
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220727-26-4
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Skin Sens. 1 |
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R-GLYCIDOL
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404-660-4
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57044-25-4
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Self-react. C; Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 3; Acute Tox. 4; Skin Corr. 1B |
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277-299-1
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73138-82-6
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Skin Sens. 1 |
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A complex combination derived from tall oil. Composed primarily of tricyclic monocarboxylic acids, mainly abietic and dehydroabietic acids. Includes tall-oil rosin stabilized by catalytic disproportionation.
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232-484-6
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8052-10-6
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Skin Sens. 1 |
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A complex combination derived from wood, especially pine wood. Composed primarily of resin acids and modified resin acids such as dimers and decarboxylated resin acids. Includes rosin stabilized by catalytic disproportionation.
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232-475-7
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8050-09-7
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Skin Sens. 1 |
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203-585-2
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108-46-3
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Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2 |
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233-940-7
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10453-86-8
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Acute Tox. 4 |
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A complex combination of hydrocarbons produced as the residual fraction from the distillation of heavy coker gas oil and vacuum gas oil. It predominantly consists of hydrocarbons having carbon numbers predominantly greater than C13 and boiling above approximately 230°C (446°F).
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270-796-4
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68478-17-1
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Carc. 1B |
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A complex combination of hydrocarbons obtained by the treatment and distillation of raw steam-cracked naphtha. It consists predominantly of unsaturated hydrocarbons boiling in the range above approximately 180°C (356°F).
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308-733-0
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98219-64-8
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Carc. 1B |
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A complex residuum from the vacuum distillation of the residuum from the atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly greater than C13 and boiling above approximately 230°C (446°F).
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270-984-6
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68512-62-9
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Carc. 1B |
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A very complex combination of hydrocarbons produced as the residual fraction from the distillation of vacuum residuum and the products from a thermal cracking process. It consists predominantly of hydrocarbons having carbon numbers predominantly greater than C20 and boiling above approximately 350°C (662°F). This stream is likely to contain 5 wt. % or more of 4- to 6-membered condensed ring aromatic hydrocarbons.
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272-187-9
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68783-13-1
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Carc. 1B |
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A complex residuum from the vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists predominantly of hydrocarbons having carbon numbers predominantly greater than C24 and boiling above approximately 390°C (734°F).
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292-658-2
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90669-76-4
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Carc. 1B |
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A low-sulfur complex combination of hydrocarbons produced as the residual fraction from the topping plant distillation of crude oil. It is the residuum after the straight-run gasoline cut, kerosene cut and gas oil cut have been removed.
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271-763-7
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68607-30-7
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Carc. 1B |
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A complex combination of hydrocarbons produced as the residual fraction from distillation of the product from a thermal cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly greater than C20 and boiling above approximately 350°C (662°F). This stream is likely to contain 5 wt. % or more of 4- to 6-membered condensed ring aromatic hydrocarbons.
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265-081-9
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64741-80-6
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Carc. 1B |
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A complex combination of hydrocarbons obtained as the residual fraction from the distillation of the products of a steam cracking process (including steam cracking to produce ethylene). It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly greater than C14 and boiling above approximately 260°C (500°F). This stream is likely to contain 5 wt. % or more of 4- to 6-membered condensed ring aromatic hydrocarbons.
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265-193-8
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64742-90-1
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Carc. 1B |
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A complex residuum from the distillation of steam-cracked petroleum residues.
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273-272-3
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68955-36-2
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Carc. 1B |
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A complex combination of hydrocarbons obtained during the production of refined petroleum tar by the distillation of steam cracked tar. It consists predominantly of aromatic and other hydrocarbons and organic sulfur compounds.
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292-657-7
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90669-75-3
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Carc. 1B |
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A complex combination of hydrocarbons obtained as a column bottom from the separation of effluents from steam cracking naphtha at a high temperature. It boils in the range of approximately 147°C to 300°C (297°F to 572°F) and produces a finished oil having a viscosity of 18cSt at 50°C.
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295-517-3
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92062-04-9
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Carc. 1B |
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A complex residuum from the distillation of the products from a steam-cracking process. It consists predominantly of aromatic and unsaturated hydrocarbons having carbon numbers greater than C7 and boiling in the range of approximately 101°C to 555°C (214°F to 1030°F).
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271-013-9
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68513-69-9
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Carc. 1B |
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A complex combination of hydrocarbons obtained by the distillation of the products of steam cracking or similar processes after taking off the very light products resulting in a residue starting with hydrocarbons having carbon numbers greater than C5. It consists predominantly of aromatic hydrocarbons having carbon numbers greater than C5 and boiling above approximately 40°C (104°F).
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310-057-6
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102110-55-4
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Carc. 1B; Muta. 1B; Asp. Tox. 1 |
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