cosmetics-restricted-subs

Cosmetic Products Regulation, Annex III - Restricted Substances

EU. Restricted Substances: Annex III, Regulation 1223/2009/EC on Cosmetic Products, as amended by Regulation (EU) 2022/2195, OJ L 292, 11 November 2022

This list contains substances whose use in cosmetic products in the European Union is banned, except under certain conditions as indicated in Annex III. The list specifies the field of application or use, maximum allowable concentration limits in finished products, and any additional limitations.

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Last updated 02 June 2023. Database contains 651 unique substances/entries.
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Showing 351 - 400 of 651 results.
Substance Name
EC No.
CAS No.
Ref No.
Restrictions  
Product type, body parts
Maximum Threshold
Restriction(s)
Pyridinium, 1-methyl-4-[(methylphenylhydrazono)methyl]-, methyl sulfate
269-503-2
68259-00-7
275
Hair dye substance in oxidative hair dye products
1 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.0 %
 Details
2-[(4-Aminophenyl)azo]-1,3-dimethyl-1H-imidazolium chloride
306-764-4
97404-02-9
276
Hair dye substance in oxidative hair dye products
0.5 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5 %
 Details
2-[(4-Aminophenyl)azo]-1,3-dimethyl-1H-imidazolium chloride
306-764-4
97404-02-9
276
Hair dye substance in non-oxidative hair dye products
1 %
Details
2,6-Pyridinediamine, 3-(3-pyridinylazo)
AZOGELB
421-430-9
28365-08-4
277
Hair dye substance in oxidative hair dye products
0.25 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.25 %
 Details
2,6-Pyridinediamine, 3-(3-pyridinylazo)
AZOGELB
421-430-9
28365-08-4
277
Hair dye substance in non-oxidative hair dye products
0.25 %
Details
4-((4-Amino-3-methylphenyl)(4-imino-3-methyl-2,5-cyclohexadien-1-ylidene)methyl)-2-methylphenylamine monohydrochloride;CI 42520
221-831-7
3248-91-7
278
Hair dye substance in oxidative hair dye products
1 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.0 %
 Details
4-((4-Amino-3-methylphenyl)(4-imino-3-methyl-2,5-cyclohexadien-1-ylidene)methyl)-2-methylphenylamine monohydrochloride;CI 42520
221-831-7
3248-91-7
278
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
2,3-Diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]Pyrazol-1-one dimethanesulfonate
469-500-8
857035-95-1
279
Hair dye substance in oxidative hair dye products
2 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2.0 %
 Details
Dipotassium fluorophosphate
237-957-0
14104-28-0
28
Oral products
0.15 %
When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0.15 %
 Details
2-Amino-4,6-dinitrophenol
202-544-6
96-91-3
280
Hair dye substance in oxidative hair dye products
0.6 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.6 %
 Details
2-Amino-4,6-dinitrophenol
202-544-6
96-91-3
280
Hair dye substance in non-oxidative hair dye products
0.6 %
Details
2-Amino-4,6-dinitrophenol, sodium salt
212-603-8
831-52-7
280
Hair dye substance in non-oxidative hair dye products
0.6 %
Details
2-Amino-4,6-dinitrophenol, sodium salt
212-603-8
831-52-7
280
Hair dye substance in oxidative hair dye products
0.6 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.6 %
 Details
1-Methylamino-2-nitro-5-(2,3-dihydroxy-propyloxy)-benzene
279-383-3
80062-31-3
281
Hair dye substance in oxidative hair dye products
0.8 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.8 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
1-Methylamino-2-nitro-5-(2,3-dihydroxy-propyloxy)-benzene
279-383-3
80062-31-3
281
Hair dye substance in non-oxidative hair dye products
1 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
1-Propanaminium, 3-[[9,10-dihydro-4-(methylamino)-9,10-dioxo-1-anthracenyl]amino]-N,N-dimethyl-N-propyl-, bromide
481-170-7
502453-61-4
282
Hair dye substance in non-oxidative hair dye products
3 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
3-Amino-2-chloro-6-methylphenol
283-144-9
84540-50-1
283
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
3-Amino-2-chloro-6-methylphenol
283-144-9
84540-50-1
283
Hair dye substance in oxidative hair dye products
1 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.0 %
 Details
3-Amino-4-chloro-6-methylphenol HCl
-
80419-48-3
283
Hair dye substance in oxidative hair dye products
1 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.0 %
 Details
3-Amino-4-chloro-6-methylphenol HCl
-
80419-48-3
283
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
2,2'-Methylenebis(4-aminophenol)
-
63969-46-0
284
Hair dye substance in oxidative hair dye products
1 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.0 %
 Details
2,2'-Methylenebis(4-aminophenol)
-
63969-46-0
284
Hair dye substance in non-oxidative hair dye products
1 %
Details
Phenol, 2,2'-methylenebis[4-amino-], dihydrochloride
440-850-3
27311-52-0
284
Hair dye substance in non-oxidative hair dye products
1 %
Details
Phenol, 2,2'-methylenebis[4-amino-], dihydrochloride
440-850-3
27311-52-0
284
Hair dye substance in oxidative hair dye products
1 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.0 %
 Details
Pyridine-2,6-diyldiamine
205-507-2
141-86-6
285
Professional use cosmetic products for coloring eyelashes
0.15 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.15 %
For professional use only
 Details
Pyridine-2,6-diyldiamine
205-507-2
141-86-6
285
Hair dye substance in oxidative hair dye products
0.15 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.15 %
 Details
C16-alkyltrimethylammonium chloride
203-928-6
112-02-7
286
Rinse-off hair products
2.5 %
For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product
 Details
C16-alkyltrimethylammonium chloride
203-928-6
112-02-7
286
Leave-on face products
0.5 %
For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product
 Details
C18-alkyltrimethylammonium chloride
203-929-1
112-03-8
286
Leave-on face products
0.5 %
For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product
 Details
C18-alkyltrimethylammonium chloride
203-929-1
112-03-8
286
Rinse-off hair products
2.5 %
For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product
 Details
C22-alkyltrimethylammonium chloride
241-327-0
17301-53-0
287
Leave-on hair products
3 %
For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product
 Details
C22-alkyltrimethylammonium chloride
241-327-0
17301-53-0
287
Leave-on face products
3 %
For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product
 Details
C22-alkyltrimethylammonium chloride
241-327-0
17301-53-0
287
Rinse-off hair products
5 %
For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product
 Details
3-[(4-amino-3-methyl-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-N,N,N-trimethylpropan-1-aminium, methylsulfate salt
605-392-2
16517-75-2
288
Hair dye substance in non-oxidative hair dye products
2 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
3-[(4-amino-3-methyl-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-N,N,N-trimethylpropan-1-aminium, methylsulfate salt
605-392-2
16517-75-2
288
Hair dye substance in oxidative hair dye products
2 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2.0 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
Phosphoric acid compound with 4-[(2,6-dichlorophenyl) (4-imino-3,5-dimethyl-2,5-cyclohexadien-1-ylidene) methyl]-2,6-dimethylaniline (1:1)
277-929-5
74578-10-2
289
Hair dye substance in oxidative hair dye products
0.2 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.2 %
 Details
Phosphoric acid compound with 4-[(2,6-dichlorophenyl) (4-imino-3,5-dimethyl-2,5-cyclohexadien-1-ylidene) methyl]-2,6-dimethylaniline (1:1)
277-929-5
74578-10-2
289
Hair dye substance in non-oxidative hair dye products
0.2 %
Details
Calcium fluorophosphate
232-187-1
7789-74-4
29
Oral products
0.15 %
When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0.15 %
 Details
Disodium 2,2'-(9,10-dioxoanthracene-1,4-diyldiimino)bis(5-methylsulphonate)
224-546-6
4403-90-1
290
Hair dye substance in non-oxidative hair dye products
0.3 %
Details
Sodium, 4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]toluene-3-sulphonate
224-618-7
4430-18-6
291
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
1,4-Benzenediamine, 2-(methoxymethyl)
679-526-3
337906-36-2
292
Hair dye substance in oxidative hair dye products
1.8 %
After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1.8 % (calculated as free base)
 Details
1,4-Benzenediamine, 2-(methoxymethyl)
679-526-3
337906-36-2
292
Products intended for colouring eyelashes
1.8 %
After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1.8 % (calculated as free base). Professional use
 Details
1,4-Benzenediamine, 2-(methoxymethyl)-, sulfate
638-749-6
337906-37-3
292
Products intended for colouring eyelashes
1.8 %
After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1.8 % (calculated as free base). Professional use
 Details
1,4-Benzenediamine, 2-(methoxymethyl)-, sulfate
638-749-6
337906-37-3
292
Hair dye substance in oxidative hair dye products
1.8 %
After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1.8 % (calculated as free base)
 Details
1-N-Methylmorpholiniumpropylamino-4-hydroxyanthraquinone, methyl sulfate
254-161-9
38866-20-5
293
Hair dye substance in non-oxidative hair dye products
0.5 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
Ethanol, 2,2'-[[3-methyl-4-[(E)-(4-nitrophenyl)azo]phenyl]imino]bis-
221-665-5
3179-89-3
294
Hair dye substance in non-oxidative hair dye products
0.2 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
Ethanol, 2,2'-[[3-methyl-4-[(E)-(4-nitrophenyl)azo]phenyl]imino]bis-
221-665-5
3179-89-3
294
Hair dye substance in oxidative hair dye products
2 %
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2.0 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
4-Amino-5-hydroxy-3-(4-nitrophenylazo)-6-(phenylazo)-2,7-naphthalenedisulfonic acid, disodium salt
213-903-1
1064-48-8
295
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
Disodium 3-hydroxy-4-[(E)-(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate
227-497-9
5858-81-1
296
Hair dye substance in non-oxidative hair dye products
0.4 %
Details
2-(2-Ethoxyethoxy)ethanol;DEGEE;Diethylene Glycol Monoethyl Ether
203-919-7
111-90-0
297
The following spray products: fine fragrances, hair sprays, anti-perspirants and deodorants
2.6 %
The level of ethylene glycol impurity in Ethoxydiglycol must be ≤ 0.1%
Not to be used in eye products and oral products
 Details
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