cosmetics-restricted-subs

Cosmetic Products Regulation, Annex III - Restricted Substances

EU. Restricted Substances: Annex III, Regulation 1223/2009/EC on Cosmetic Products, as amended by Regulation (EU) 2022/2195, OJ L 292, 11 November 2022

This list contains substances whose use in cosmetic products in the European Union is banned, except under certain conditions as indicated in Annex III. The list specifies the field of application or use, maximum allowable concentration limits in finished products, and any additional limitations.

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Last updated 09 June 2023. Database contains 651 unique substances/entries.
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Showing 251 - 300 of 651 results.
Substance Name
EC No.
CAS No.
Ref No.
Restrictions  
Product type, body parts
Maximum Threshold
Restriction(s)
2-[(2-methoxy-4-nitrophenyl)amino]ethanol
266-138-0
66095-81-6
236
Hair dye substance in non-oxidative hair dye products
0.2 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
2-[(2-Nitrophenyl)amino]ethanol
225-555-8
4926-55-0
255
Hair dye substance in non-oxidative hair dye products
1 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
2-[(4-Aminophenyl)azo]-1,3-dimethyl-1H-imidazolium chloride
306-764-4
97404-02-9
276
Hair dye substance in non-oxidative hair dye products
1 %
Details
2-[3-(methylamino)-4-nitrophenoxy]ethanol
261-940-7
59820-63-2
235
Hair dye substance in non-oxidative hair dye products
0.15 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
2-[[4-(Dimethylamino)phenyl]azo]-1,3-dimethyl-1H-imidazolium chloride
278-601-4
77061-58-6
268
Hair dye substance in non-oxidative hair dye products
1 %
Details
2-[bis(2-Hydroxyethyl)amino]-5-nitrophenol
HC YELLOW NO. 4
428-840-7
59820-43-8
253
Hair dye substance in non-oxidative hair dye products
1.5 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
2-Amino-4,6-dinitrophenol
202-544-6
96-91-3
280
Hair dye substance in non-oxidative hair dye products
0.6 %
Details
2-Amino-4,6-dinitrophenol, sodium salt
212-603-8
831-52-7
280
Hair dye substance in non-oxidative hair dye products
0.6 %
Details
2-Amino-6-chloro-4-nitrophenol
228-762-1
6358-09-4
252
Hair dye substance in non-oxidative hair dye products
2 %
Details
2-Naphthalenaminium, 8-[(4-amino-3-nitrophenyl)azo]-7-hydroxy-N,N,N-trimethyl-, chloride
269-944-0
68391-32-2
304
Hair dye substance in non-oxidative hair dye products
2 %
Details
2-Nitro-N1-phenylbenzene-1,4-diamine
220-494-3
2784-89-6
258
Hair dye substance in non-oxidative hair dye products
1 %
Details
3-[(4-amino-3-methyl-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-N,N,N-trimethylpropan-1-aminium, methylsulfate salt
605-392-2
16517-75-2
288
Hair dye substance in non-oxidative hair dye products
2 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
3-Amino-2,4-dichlorophenol
262-909-0
61693-42-3
227
Hair dye substance in non-oxidative hair dye products
1.5 %
Details
3-Amino-2,4-dichlorophenol HCl
612-192-9
61693-43-4
227
Hair dye substance in non-oxidative hair dye products
1.5 %
Details
3-Amino-2-chloro-6-methylphenol
283-144-9
84540-50-1
283
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
3-Amino-4-chloro-6-methylphenol HCl
-
80419-48-3
283
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
3-Amino-7-(dimethylamino)-2-methoxyphenoxazin-5-ium chloride
267-370-5
67846-56-4
305
Hair dye substance in non-oxidative hair dye products
0.5 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
4,4'-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine
279-845-4
81892-72-0
226
Hair dye substance in non-oxidative hair dye products
1.8 %
Details
4,4'-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine
279-845-4
81892-72-0
226
Hair dye substance in non-oxidative hair dye products
1.2 %
Details
4,4'-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine tetrahydrochloride salt
278-022-7
74918-21-1
226
Hair dye substance in non-oxidative hair dye products
1.2 %
Details
4,4'-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine tetrahydrochloride salt
278-022-7
74918-21-1
226
Hair dye substance in non-oxidative hair dye products
1.8 %
Details
4-((4-Amino-3-methylphenyl)(4-imino-3-methyl-2,5-cyclohexadien-1-ylidene)methyl)-2-methylphenylamine monohydrochloride;CI 42520
221-831-7
3248-91-7
278
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
4-[(2-Hydroxyethyl)amino]-3-nitrophenol
265-648-0
65235-31-6
248
Hair dye substance in non-oxidative hair dye products
1.85 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
4-[(2-Nitrophenyl)amino]phenol
259-132-4
54381-08-7
256
Hair dye substance in non-oxidative hair dye products
1 %
Details
4-Amino-3-nitrophenol
210-236-8
610-81-1
215
Hair dye substance in non-oxidative hair dye products
1 %
Details
4-Amino-5-hydroxy-3-(4-nitrophenylazo)-6-(phenylazo)-2,7-naphthalenedisulfonic acid, disodium salt
213-903-1
1064-48-8
295
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
6-Methoxy-N2-methyl-2,3-pyridinediamine dihydrochloride salt
280-622-9
83732-72-3
203
Hair dye substance in non-oxidative hair dye products
0.68 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
6-Methoxy-N2-methyl-2,3-pyridinediamine dihydrochloride salt
280-622-9
83732-72-3
203
Hair dye substance in non-oxidative hair dye products
1 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
6-Methoxy-N2-methyl-2,3-pyridinediamine hydrochloride salt
620-557-9
90817-34-8
203
Hair dye substance in non-oxidative hair dye products
1 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
6-Methoxy-N2-methyl-2,3-pyridinediamine hydrochloride salt
620-557-9
90817-34-8
203
Hair dye substance in non-oxidative hair dye products
0.68 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
9,10-Anthracenedione, 1,4-bis[(2,3-dihydroxypropyl)amino]-
421-470-7
99788-75-7
264
Hair dye substance in non-oxidative hair dye products
0.3 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
[7-Hydroxy-8-[(2-methoxyphenyl)azo]-2-naphthyl]trimethylammonium chloride
269-941-4
68391-30-0
267
Hair dye substance in non-oxidative hair dye products
2 %
Details
Benzenaminium, 3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo]-N,N,Ntrimethyl-, chloride
269-943-5
68391-31-1
262
Hair dye substance in non-oxidative hair dye products
2 %
Details
Benzenemethanaminium, N-ethyl-N-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(2-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, hydroxide, inner salt, aluminum salt
272-939-6
68921-42-6
190
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
Benzenemethanaminium, N-ethyl-N-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(2-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, hydroxide, inner salt, diammonium salt;CI 42090
220-168-0
2650-18-2
190
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
Benzenemethanaminium, N-ethyl-N-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(2-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, hydroxide, inner salt, disodium salt
223-339-8
3844-45-9
190
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
CI 10316;Disodium 5,7-dinitro-8-oxido-2-naphthalenesulfonate
212-690-2
846-70-8
214
Hair dye substance in non-oxidative hair dye products
0.2 %
Details
CI 16035;Disodium 6-hydroxy-5-[(2-methoxy-4-sulphonato-m-tolyl)azo]naphthalene-2-sulphonate
247-368-0
25956-17-6
191
Hair dye substance in non-oxidative hair dye products
0.4 %
Details
CI 16255;Trisodium 1-(1-naphthylazo)-2-hydroxynaphthalene-4',6,8-trisulphonate
220-036-2
2611-82-7
192
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
CI 17200;Disodium 5-amino-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonate
222-656-9
3567-66-6
254
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
CI 19140;Trisodium 5-hydroxy-1-(4-sulphophenyl)-4-(4-sulphophenylazo)pyrazole-3-carboxylate and aluminium lake
217-699-5
1934-21-0
189
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
CI 45100;Hydrogen 3,6-bis(diethylamino)-9-(2,4-disulphonatophenyl)xanthylium, sodium salt
222-529-8
3520-42-1
193
Hair dye substance in non-oxidative hair dye products
0.6 %
Details
CI 45410;Fluorescein, 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-, disodium salt
242-355-6
18472-87-2
270
Hair dye substance in non-oxidative hair dye products
0.4 %
Details
CI 62045;Sodium 1-amino-4-(cyclohexylamino)-9,10-dihydro-9,10-dioxoanthracene-2-sulphonate
224-460-9
4368-56-3
195
Hair dye substance in non-oxidative hair dye products
0.5 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
Di-[2-[(E)-2-[4-[bis(2-hydroxyethyl)aminophenyl]vinyl]pyridin-1-ium]-ethyl]disulphide dimethanesulfonate
-
1449653-83-1
317
Hair dye substance in non-oxidative hair dye products
0.5 %
As from 3 June 2021: 0.5 % (maximum concentration in ready use preparation). Methanesulfonates impurities, in particular ethyl methanesulfonate shall not be present
 Details
Di[2-[4-[(E)-2-[2,4,5-trimethoxyphenyl]vinyl] pyridinin-1-ium] butanoyl]aminoethyl]disulfanyl dichloride
805-402-7
1450801-55-4
299
Hair dye substance in non-oxidative hair dye products
0.5 %
Details
Di[2-[4-[(E)-2-[4-[bis(2-hydroxyethyl)aminophenyl]vinyl]pyridin-1-ium] butanoyl]aminoethyl] di-sulfanyl dichloride
805-105-2
1449471-67-3
298
Hair dye substance in non-oxidative hair dye products
0.5 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg /kg
Keep in nitrite-free containers
 Details
Disodium 2,2'-(9,10-dioxoanthracene-1,4-diyldiimino)bis(5-methylsulphonate)
224-546-6
4403-90-1
290
Hair dye substance in non-oxidative hair dye products
0.3 %
Details
Disodium 3-hydroxy-4-[(E)-(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate
227-497-9
5858-81-1
296
Hair dye substance in non-oxidative hair dye products
0.4 %
Details
Ethanol, 2,2'-[(2-nitro-1,4-phenylene)diimino]bis-(9CI)
281-856-4
84041-77-0
8c
Hair dye substance in non-oxidative hair dye products
1.5 %
Do not use with nitrosating agents
Maximum nitrosamine content: 50 μg/kg
Keep in nitrite-free containers
 Details
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