cosmetics-prohibited-subs

cosmetics-prohibited-subs

Cosmetic Products Regulation, Annex II - Prohibited Substances

EU. Prohibited Substances: Annex II, Regulation 1223/2009/EC on Cosmetic Products, as amended by Regulation (EU) 2023/1490, OJ L 183, 20 July 2023

This list contains substances which are banned from use in any cosmetic products marketed for sale or use in the European Union.

Last updated 19 April 2024. Database contains 2528 unique substances/entries.

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Substance Name	EC No.	CAS No.	Ref No.	Product type, body parts	Maximum Threshold	Restriction(s)
Nickel dilactate	-	16039-61-5	1433	All cosmetic products	0 %		Details
Nickel potassium fluoride	-	11132-10-8	1435	All cosmetic products	0 %		Details
Nitrite(1-)	-	14797-65-0	248	All cosmetic products	0 %		Details
Nitrocresols	-	12167-20-3	250	All cosmetic products	0 %		Details
Nitroderivatives of carbazole	-	-	72	All cosmetic products	0 %		Details
Nitrosamines	-	-	410	All cosmetic products	0 %		Details
Nitrostilbenes, their homologues and their derivatives	-	-	256	All cosmetic products	0 %		Details
Normal salts, complexes and hydrofluorides of hydrofluoric acid	-	-	191	All cosmetic products	0 %	Not permitted except for those given in Annex III	Details
O,O'-Diacetyl-N-allyl-N-normorphine	-	2748-74-5	117	All cosmetic products	0 %		Details
o-Dianisidine based azo dyes show/hide 3,3'-dihydroxy-N,N'-(3,3'-dimethoxybiphenyl-4,4'-diyl)di-2-naphthamide EC / List no: 202-108-5 \| CAS no: 91-92-9 Disodium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis(4-hydroxynaphthalene-1-sulphonate) EC / List no: 219-382-7 \| CAS no: 2429-71-2 Tetrasodium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonate] EC / List no: 219-385-3 \| CAS no: 2429-74-5 1-Naphthalenesulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(4-hydroxy-, lithium salt (1:2) EC / List no: - \| CAS no: 75673-34-6 3,3'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[2,5-bis(p-nitrophenyl)-2H-tetrazolium] dichloride EC / List no: 214-665-1 \| CAS no: 1184-43-6 Tetrasodium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4,5-dihydroxynaphthalene-2,7-disulphonate] EC / List no: 224-091-3 \| CAS no: 4198-19-0 Tetrasodium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-(acetylamino)-4-hydroxynaphthalene-2,7-disulphonate] EC / List no: 267-711-8 \| CAS no: 67906-44-9 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one] EC / List no: 229-389-7 \| CAS no: 6505-29-9 Tetralithium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonate] EC / List no: 275-603-7 \| CAS no: 71550-22-6 3,3'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[5-[4-(aminothioxomethyl)phenyl]-2-(p-nitrophenyl)-2H-tetrazolium] dichloride EC / List no: 253-257-8 \| CAS no: 36889-43-7 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)diazo]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, sodium salt EC / List no: 273-439-0 \| CAS no: 68966-50-7 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)diazo]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, sodium salt, compound with 2,2'-iminodiethanol EC / List no: 273-433-8 \| CAS no: 68966-43-8 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-hydroxy-N-phenylnaphthalene-2-carboxamide] EC / List no: 233-354-1 \| CAS no: 10127-03-4 Tetrasodium 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[azo(2-amino-5-hydroxy-7-sulphonato-6,1-naphthylene)azo]]bis[5-nitrobenzoate] EC / List no: 274-429-9 \| CAS no: 70210-33-2 2-Naphthalenecarboxamide, N,N'-(3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(3-hydroxy-, disodium salt EC / List no: - \| CAS no: 52735-88-3 Copper, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-2,7-naphthalenedisulfonate) morpholine ammonium lithium sodium complexes EC / List no: - \| CAS no: 96591-22-9 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[2,4-dihydro-5-methyl-2-(p-tolyl)-3H-pyrazol-3-one] EC / List no: 229-986-2 \| CAS no: 6883-91-6 5,5'-(3,3'-Dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(1-(4-nitrophenyl)-3-phenylformazan) EC / List no: - \| CAS no: 63469-14-7 1-Naphthalenesulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(4-hydroxy-, lithium sodium salt (1:1:1) EC / List no: - \| CAS no: 75673-35-7 N,N'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[3-oxobutyramide] EC / List no: 223-873-1 \| CAS no: 4104-12-5 Disodium 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[iminocarbonyl(2-hydroxy-4,1-phenylene)azo]]bis(3-hydroxynaphthalene-1-sulphonate) EC / List no: 274-498-5 \| CAS no: 70247-69-7 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-oxo-N-phenylbutyramide] EC / List no: 229-388-1 \| CAS no: 6505-28-8 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2-methylphenyl)-3-oxobutyramide] EC / List no: 230-458-9 \| CAS no: 7147-42-4 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-, lithium sodium salt (1:2:2) EC / List no: - \| CAS no: 75659-73-3 5,5'-diphenyl-3,3'-bis(4-nitrophenyl)-2,2'-(3,3'-dimethoxybiphenyl-4,4'-ylene)ditetrazolium dichloride EC / List no: 206-067-4 \| CAS no: 298-83-9 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-hydroxy-N-(2-methoxyphenyl)naphthalene-2-carboxamide] EC / List no: 226-614-0 \| CAS no: 5437-88-7 Benzoic acid, 4,4'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl(2-acetyl-1-oxo-2,1-ethanediyl)imino))bis-, 1,1'-dibutyl ester EC / List no: - \| CAS no: 820212-95-1 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chlorophenyl)-3-oxobutyramide] EC / List no: 241-469-3 \| CAS no: 17453-73-5 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-, lithium sodium salt (1:1:3) EC / List no: - \| CAS no: 75659-72-2 Tetrasodium 6,6'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxynaphthalene-1,3-disulphonate] EC / List no: 220-026-8 \| CAS no: 2610-05-1 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2,4-dimethylphenyl)-3-oxobutyramide] EC / List no: 229-920-2 \| CAS no: 6837-37-2 3,3'-(3,3'-dimethoxy-4,4'-biphenylene)bis(2,5-diphenyl-2H-tetrazolium) chloride EC / List no: 217-488-8 \| CAS no: 1871-22-3 Disodium 2,2'-[(3,3'-dimethoxy-4,4'-biphenylylene)bis[azo(methylimino)]]di(ethanesulphonate) EC / List no: 241-085-6 \| CAS no: 17011-51-7 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-, lithium sodium salt (1:3:1) EC / List no: - \| CAS no: 75752-17-9 Butanamide, 2,2'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(N-(chlorophenyl)-3-oxo- EC / List no: - \| CAS no: 72845-99-9 Tetrasodium 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-hydroxynaphthalene-2,7-disulphonate] EC / List no: 265-533-5 \| CAS no: 65151-33-9 6,6'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxynaphthalene-1,3-disulphonic] acid EC / List no: 223-333-5 \| CAS no: 3841-14-3	-	-	711	All cosmetic products	0 %		Details

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