cosmetics-prohibited-subs

cosmetics-prohibited-subs

Cosmetic Products Regulation, Annex II - Prohibited Substances

EU. Prohibited Substances: Annex II, Regulation 1223/2009/EC on Cosmetic Products, as amended by Regulation (EU) 2023/1490, OJ L 183, 20 July 2023

This list contains substances which are banned from use in any cosmetic products marketed for sale or use in the European Union.

Last updated 18 April 2024. Database contains 2528 unique substances/entries.

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Showing 1,751 - 1,800 of 2,528 results.

Substance Name	EC No.	CAS No.	Ref No.	Product type, body parts	Maximum Threshold	Restriction(s)
Nickel(II) neodecanoate	287-469-7	85508-44-7	1460	All cosmetic products	0 %		Details
Nickel(II) neononanoate	300-094-6	93920-10-6	1460	All cosmetic products	0 %		Details
Nickel(II) neoundecanoate	300-093-0	93920-09-3	1460	All cosmetic products	0 %		Details
Nickel(II) octanoate	225-656-7	4995-91-9	1434	All cosmetic products	0 %		Details
Nickel(II) palmitate	237-138-8	13654-40-5	1460	All cosmetic products	0 %		Details
Nickel(II) propionate	222-102-6	3349-08-4	1460	All cosmetic products	0 %		Details
Nickel(II) selenite	233-263-7	10101-96-9	1454	All cosmetic products	0 %		Details
Nickel(II) silicate	244-578-4	21784-78-1	1442	All cosmetic products	0 %		Details
Nickel(II) stearate	218-744-1	2223-95-2	1432	All cosmetic products	0 %		Details
Nickel(II) sulfite	231-827-7	7757-95-1	1461	All cosmetic products	0 %		Details
Nickel(II) trifluoroacetate	240-235-8	16083-14-0	1460	All cosmetic products	0 %		Details
Nicotine	200-193-3	54-11-5	246	All cosmetic products	0 %		Details
Nigrosine	616-852-7	8005-03-6	1359	Hair dye products	0 %		Details
Nigrosine spirit soluble	601-023-4	11099-03-9	1274	Hair dye products	0 %		Details
Nitric acid, nickel salt	238-076-4	14216-75-2	1420	All cosmetic products	0 %		Details
Nitrite(1-)	-	14797-65-0	248	All cosmetic products	0 %		Details
Nitrobenzene	202-716-0	98-95-3	249	All cosmetic products	0 %		Details
Nitrocresols	-	12167-20-3	250	All cosmetic products	0 %		Details
Nitroderivatives of carbazole	-	-	72	All cosmetic products	0 %		Details
Nitrofen	217-406-0	1836-75-5	697	All cosmetic products	0 %		Details
Nitrofurantoin	200-646-5	67-20-9	251	All cosmetic products	0 %		Details
Nitrosamines	-	-	410	All cosmetic products	0 %		Details
Nitrosodipropylamine	210-698-0	621-64-7	410	All cosmetic products	0 %		Details
Nitrostilbenes, their homologues and their derivatives	-	-	256	All cosmetic products	0 %		Details
Nitroxoline	223-662-4	4008-48-4	209	All cosmetic products	0 %		Details
Nonadecafluorodecanoic acid	206-400-3	335-76-2	1604	All cosmetic products	0 %		Details
Nonylphenol	246-672-0	25154-52-3	1168	All cosmetic products	0 %		Details
Noradrenaline	200-096-6	51-41-2	257	All cosmetic products	0 %		Details
Normal salts, complexes and hydrofluorides of hydrofluoric acid	-	-	191	All cosmetic products	0 %	Not permitted except for those given in Annex III	Details
Noscapine	204-899-2	128-62-1	258	All cosmetic products	0 %		Details
O,O'-(Ethenylmethylsilylene) di[(4-methylpentan-2-one) oxime] ASIL-322; OS-5200	421-870-1	156145-66-3	1185	All cosmetic products	0 %		Details
O,O'-Diacetyl-N-allyl-N-normorphine	-	2748-74-5	117	All cosmetic products	0 %		Details
O,O'-Diethyl-O-4-nitrophenyl phosphorothioate	200-271-7	56-38-2	131	All cosmetic products	0 %		Details
o-(p-Isocyanatobenzyl)phenyl isocyanate	227-534-9	5873-54-1	1533	All cosmetic products	0 %		Details
o-Aminophenol sulphate	267-335-4	67845-79-8	1372	All cosmetic products	0 %		Details
o-Anisidine	201-963-1	90-04-0	708	All cosmetic products	0 %		Details
o-Dianisidine based azo dyes show/hide Tetrasodium 6,6'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxynaphthalene-1,3-disulphonate] EC / List no: 220-026-8 \| CAS no: 2610-05-1 Disodium 2,2'-[(3,3'-dimethoxy-4,4'-biphenylylene)bis[azo(methylimino)]]di(ethanesulphonate) EC / List no: 241-085-6 \| CAS no: 17011-51-7 Tetrasodium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-(acetylamino)-4-hydroxynaphthalene-2,7-disulphonate] EC / List no: 267-711-8 \| CAS no: 67906-44-9 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-hydroxy-N-phenylnaphthalene-2-carboxamide] EC / List no: 233-354-1 \| CAS no: 10127-03-4 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[2,4-dihydro-5-methyl-2-(p-tolyl)-3H-pyrazol-3-one] EC / List no: 229-986-2 \| CAS no: 6883-91-6 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2,4-dimethylphenyl)-3-oxobutyramide] EC / List no: 229-920-2 \| CAS no: 6837-37-2 1-Naphthalenesulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(4-hydroxy-, lithium sodium salt (1:1:1) EC / List no: - \| CAS no: 75673-35-7 3,3'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[5-[4-(aminothioxomethyl)phenyl]-2-(p-nitrophenyl)-2H-tetrazolium] dichloride EC / List no: 253-257-8 \| CAS no: 36889-43-7 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2-methylphenyl)-3-oxobutyramide] EC / List no: 230-458-9 \| CAS no: 7147-42-4 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one] EC / List no: 229-389-7 \| CAS no: 6505-29-9 Benzoic acid, 4,4'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl(2-acetyl-1-oxo-2,1-ethanediyl)imino))bis-, 1,1'-dibutyl ester EC / List no: - \| CAS no: 820212-95-1 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-oxo-N-phenylbutyramide] EC / List no: 229-388-1 \| CAS no: 6505-28-8 3,3'-(3,3'-dimethoxy-4,4'-biphenylene)bis(2,5-diphenyl-2H-tetrazolium) chloride EC / List no: 217-488-8 \| CAS no: 1871-22-3 N,N'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[3-oxobutyramide] EC / List no: 223-873-1 \| CAS no: 4104-12-5 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)diazo]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, sodium salt, compound with 2,2'-iminodiethanol EC / List no: 273-433-8 \| CAS no: 68966-43-8 Copper, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-2,7-naphthalenedisulfonate) morpholine ammonium lithium sodium complexes EC / List no: - \| CAS no: 96591-22-9 3,3'-dihydroxy-N,N'-(3,3'-dimethoxybiphenyl-4,4'-diyl)di-2-naphthamide EC / List no: 202-108-5 \| CAS no: 91-92-9 Tetralithium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonate] EC / List no: 275-603-7 \| CAS no: 71550-22-6 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chlorophenyl)-3-oxobutyramide] EC / List no: 241-469-3 \| CAS no: 17453-73-5 Tetrasodium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonate] EC / List no: 219-385-3 \| CAS no: 2429-74-5 6,6'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxynaphthalene-1,3-disulphonic] acid EC / List no: 223-333-5 \| CAS no: 3841-14-3 5,5'-diphenyl-3,3'-bis(4-nitrophenyl)-2,2'-(3,3'-dimethoxybiphenyl-4,4'-ylene)ditetrazolium dichloride EC / List no: 206-067-4 \| CAS no: 298-83-9 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-, lithium sodium salt (1:3:1) EC / List no: - \| CAS no: 75752-17-9 Tetrasodium 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-hydroxynaphthalene-2,7-disulphonate] EC / List no: 265-533-5 \| CAS no: 65151-33-9 Tetrasodium 2,2'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[azo(2-amino-5-hydroxy-7-sulphonato-6,1-naphthylene)azo]]bis[5-nitrobenzoate] EC / List no: 274-429-9 \| CAS no: 70210-33-2 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-, lithium sodium salt (1:2:2) EC / List no: - \| CAS no: 75659-73-3 1-Naphthalenesulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(4-hydroxy-, lithium salt (1:2) EC / List no: - \| CAS no: 75673-34-6 Butanamide, 2,2'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(N-(chlorophenyl)-3-oxo- EC / List no: - \| CAS no: 72845-99-9 Disodium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis(4-hydroxynaphthalene-1-sulphonate) EC / List no: 219-382-7 \| CAS no: 2429-71-2 2-Naphthalenecarboxamide, N,N'-(3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(3-hydroxy-, disodium salt EC / List no: - \| CAS no: 52735-88-3 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-hydroxy-N-(2-methoxyphenyl)naphthalene-2-carboxamide] EC / List no: 226-614-0 \| CAS no: 5437-88-7 Tetrasodium 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4,5-dihydroxynaphthalene-2,7-disulphonate] EC / List no: 224-091-3 \| CAS no: 4198-19-0 3,3'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[2,5-bis(p-nitrophenyl)-2H-tetrazolium] dichloride EC / List no: 214-665-1 \| CAS no: 1184-43-6 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-, lithium sodium salt (1:1:3) EC / List no: - \| CAS no: 75659-72-2 5,5'-(3,3'-Dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(1-(4-nitrophenyl)-3-phenylformazan) EC / List no: - \| CAS no: 63469-14-7 3,3'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)diazo]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, sodium salt EC / List no: 273-439-0 \| CAS no: 68966-50-7 Disodium 4,4'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[iminocarbonyl(2-hydroxy-4,1-phenylene)azo]]bis(3-hydroxynaphthalene-1-sulphonate) EC / List no: 274-498-5 \| CAS no: 70247-69-7	-	-	711	All cosmetic products	0 %		Details
O-Hexyl-N-ethoxycarbonylthiocarbamate	432-750-3	109202-58-6	1407	All cosmetic products	0 %		Details
O-Isobutyl-N-ethoxy carbonylthiocarbamate	434-350-4	103122-66-3	1405	All cosmetic products	0 %		Details
o-Phenylenediamine	202-430-6	95-54-5	363	All cosmetic products	0 %		Details
o-Tolidine based dyes show/hide Tetrasodium 6,6'-((3,3'-dimethyl-(1,1'-biphenyl-4,4'diyl)bis(azo)bis(4-amino-5-hydroxy-1,3-naphthalenedisulphonate) EC / List no: 206-242-5 \| CAS no: 314-13-6 N,N'-(3,3'-dimethylbiphenyl-4,4'-ylene)di(acetoacetamide) EC / List no: 202-111-1 \| CAS no: 91-96-3 N,N'-(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide] EC / List no: 227-783-3 \| CAS no: 5979-28-2 Tetrasodium 3,3'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonate] EC / List no: 200-786-7 \| CAS no: 72-57-1 N,N'-(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[3-oxobutyramide], disodium salt EC / List no: 271-328-1 \| CAS no: 68540-94-3 N,N'-(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(3-hydroxynaphthalene-2-carboxamide) EC / List no: 223-007-2 \| CAS no: 3692-05-5 Disodium 3,3'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[2,4-diamino-5-methylbenzenesulphonate] EC / List no: 229-024-1 \| CAS no: 6405-94-3 2,2'-[(3,3'-dimethyl-4,4'-biphenylylene)bis(azo)]bis[4-(1,1,3,3-tetramethylbutyl)phenol] EC / List no: 230-616-7 \| CAS no: 7218-82-8 Disodium 3,3'-((3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(azo)bis(4-aminonaphthalene-1-sulphonate) EC / List no: 213-594-3 \| CAS no: 992-59-6 Benzamide, 3,3'-((3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(imino(1-acetyl-2-oxo-2,1-ethanediyl)-2,1-diazenediyl))bis(4-methyl- EC / List no: - \| CAS no: 64441-14-1 Tetrasodium 3,3'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4,5-dihydroxynaphthalene-2,7-disulphonate] EC / List no: 218-432-5 \| CAS no: 2150-54-1 2,2'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-oxo-N-phenylbutyramide] EC / List no: 228-789-9 \| CAS no: 6358-88-9 2,2'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-nonylphenol] EC / List no: 268-048-7 \| CAS no: 67990-27-6 3,3'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[imino(1-acetyl-2-oxoethane-1,2-diyl)azo]]bis[bis(3-aminopropyl)(p-methoxybenzyl)methylammonium] dichloride EC / List no: 255-154-3 \| CAS no: 40948-42-3	-	-	725	All cosmetic products	0 %		Details
Octaborates	-	-	1396	All cosmetic products	0 %		Details
Octamethylcyclotetrasiloxane	209-136-7	556-67-2	1388	All cosmetic products	0 %		Details
Octamoxin	-	4684-87-1	202	All cosmetic products	0 %		Details
Octamylamine	207-947-0	502-59-0	267	All cosmetic products	0 %		Details
Octodrine	208-851-1	543-82-8	28	All cosmetic products	0 %		Details
Oestrogens	-	-	260	All cosmetic products	0 %		Details
Oil from the seeds of Laurus nobilis L. Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Laurus nobilis, Lauraceae.	283-272-5	84603-73-6	359	All cosmetic products	0 %		Details
Oleandrin	207-361-5	465-16-7	261	All cosmetic products	0 %		Details
Olivine, nickel green An inorganic pigment that is the reaction product of high temperature calcination in which nickel (II) oxide and silicon oxide in varying amounts are homogeneously and ionically interdiffused to form a crystalline matrix of olivine. Its composition may include any one or a combination of the modifiers alkali or alkaline earth halides.	271-112-7	68515-84-4	1463	All cosmetic products	0 %		Details

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