carcinogens-mutagens-dir-2004-37

Carc and Muta Directive, Annex I - Substances, Mixtures & Processes

EU. Substances, Mixtures, Related Processes: Annex I & Art. 2, Dir 2004/37/EC (CMRD), as amended by Dir (EU) 2022/431, 16 March 2022

This list contains a non-exhaustive inventory of substances based on Art. 2 carcinogen, mutagen and reprotoxin (CMR) definitions and Annex I of the Carcinogens, Mutagens and Reprotoxins Directive (CMRD). Category 1A and 1B CMRs are derived from the CLP Regulation's Table 3 of Annex VI (1272/2008/EC). Employers are obligated to minimize worker exposure to these agents as far as possible, and must arrange for medical surveillance of workers exposed to these substances.

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Last updated 01 June 2023. Database contains 1275 unique substances/entries.
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Substance Name
EC No.
CAS No.
 
(1R,2S,5R)-2-[(4-chlorophenyl)methyl]-5-propan-2-yl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol
-
115850-69-6
 Details
(1R,2S,5S)-2-[(4-chlorophenyl)methyl]-5-propan-2-yl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol
-
115937-89-8
 Details
(2-chloroethyl)(3-hydroxypropyl)ammonium chloride
CLETOPROPAMINHYDROCHLORID
429-740-6
40722-80-3
 Details
(2-ethylhexanoato-O)(isodecanoato-O)nickel
284-351-7
84852-39-1
 Details
(2-ethylhexanoato-O)(isononanoato-O)nickel
287-470-2
85508-45-8
 Details
(3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)diammonium bis(hydrogen sulphate)
265-294-7
64969-36-4
 Details
(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane
SILANEOPHAN
405-020-7
105024-66-6
 Details
(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate
2691; CARTASOL BRILLANT SCHARLACH K-2GL KONZ.; CARTASOL BRILLANTSCHARLACH K-2GL FLÜSSIG (ZUBEREITUNG); CARTASOL BRILLANTSCHARLACH K-2GL GRANULAT (ZUBEREITUNG); CARTASOL BRILLIANT SCARLET K-2GL; CARTASOL BRILLIANT SCARLET K-2GL CONC.
402-060-7
108225-03-2
 Details
(E)-3-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
CP-166,221
428-010-4
82413-20-5
 Details
(isodecanoato-O)(isononanoato-O)nickel
284-348-0
84852-36-8
 Details
(isodecanoato-O)(isooctanoato-O)nickel
285-909-2
85166-19-4
 Details
(isononanoato-O)(isooctanoato-O)nickel
287-471-8
85508-46-9
 Details
(isononanoato-O)(neodecanoato-O)nickel
287-592-6
85551-28-6
 Details
(isooctanoato-O)(neodecanoato-O)nickel
284-347-5
84852-35-7
 Details
(methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'dipyridinium dichloride dihydrochloride
CARTASOL GEEL M-GL CONC.; CARTASOL GELB M-GL FLÜSSIG (ZUBEREITUNG); CARTASOL GELB M-GL KONZ.; CARTASOL YELLOW M-GL CONC.; HM 2580
401-500-5
118658-99-4
 Details
(R)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
226-908-9
5543-58-8
 Details
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
226-907-3
5543-57-7
 Details
1,2,3-trichloropropane
202-486-1
96-18-4
 Details
1,2,4-triazole
206-022-9
288-88-0
 Details
1,2-benzenedicarboxylic acid, dihexyl ester, branched and linear
271-093-5
68515-50-4
 Details
1,2-benzenedicarboxylic acid, dipentylester, branched and linear
284-032-2
84777-06-0
 Details
1,2-benzenedicarboxylic acid; di-C6-8-branched alkylesters, C7-rich
276-158-1
71888-89-6
 Details
1,2-benzenedicarboxylic acid; di-C7-11-branched and linear alkylesters
271-084-6
68515-42-4
 Details
1,2-bis(2-methoxyethoxy)ethane; TEGDME; triethylene glycol dimethyl ether; triglyme
203-977-3
112-49-2
 Details
1,2-dibromo-3-chloropropane
202-479-3
96-12-8
 Details
1,2-dibromoethane
203-444-5
106-93-4
 Details
1,2-dichloroethane; ethylene dichloride
203-458-1
107-06-2
 Details
1,2-dichloropropane; propylene dichloride
201-152-2
78-87-5
 Details
1,2-diethoxyethane
211-076-1
629-14-1
 Details
1,2-dimethoxyethane; ethylene glycol dimethyl ether; EGDME
203-794-9
110-71-4
 Details
1,2-dimethylhydrazine
-
540-73-8
 Details
1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione; TGIC
219-514-3
2451-62-9
 Details
1,3,5-tris-[(2S and 2R)-2,3-epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione
TEPIC-H
423-400-0
59653-74-6
 Details
1,3-butadiene; buta-1,3-diene
203-450-8
106-99-0
 Details
1,3-dichloro-2-propanol
202-491-9
96-23-1
 Details
1,3-propanesultone; 1,2-oxathiolane 2,2-dioxide
214-317-9
1120-71-4
 Details
1,4,5,8-tetraaminoanthra; quinone; C.I. Disperse Blue 1
219-603-7
2475-45-8
 Details
1,4-dichlorobut-2-ene
212-121-8
764-41-0
 Details
1,4-dioxane
204-661-8
123-91-1
 Details
1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride [containing ≥ 0,1 % 4-chloroaniline (EC No 203-401-0)]
433-580-2
214353-17-0
 Details
1-bromopropane; n-propyl bromide
203-445-0
106-94-5
 Details
1-chloro-2,3-epoxypropane; epichlorhydrin
203-439-8
106-89-8
 Details
1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. residues
The complex combination of products produced by the distillation of products from a 2-ethyl-1-hexanol manufacturing process. It consists predominantly of organic compounds such as alcohols, aldehydes, esters, carboxylic acids and acetals having carbon numbers predominantly in the range of C4 through C16 and boiling in the range of 150°C to 308°C (302°F to 586°F).
271-832-1
68609-68-7
 Details
1-methyl-3-nitro-1-nitrosoguanidine
200-730-1
70-25-7
 Details
1-vinylimidazole
214-012-0
1072-63-5
 Details
2,2'-(nitrosoimino)bisethanol
214-237-4
1116-54-7
 Details
2,2'-bioxirane; 1,2:3,4-diepoxybutane
215-979-1
1464-53-5
 Details
2,2'-dichloro-4,4'-methylenedianiline; 4,4'-methylene bis(2-chloroaniline)
202-918-9
101-14-4
 Details
2,2-bis(bromomethyl)propane-1,3-diol
221-967-7
3296-90-0
 Details
2,2-dimethylpropan-1-ol, tribromo derivative
253-057-0
36483-57-5
 Details
2,3-dibromopropan-1-ol; 2,3-dibromo-1-propanol
202-480-9
96-13-9
 Details
2,3-dinitrotoluene
210-013-5
602-01-7
 Details
2,3-epoxypropan-1-ol; glycidol; oxiranemethanol
209-128-3
556-52-5
 Details
2,3-epoxypropyl methacrylate; glycidyl methacrylate
203-441-9
106-91-2
 Details
2,3-epoxypropyltrimethylammonium chloride ... %; glycidyl trimethylammonium chloride ... %
221-221-0
3033-77-0
 Details
2,4,5-trimethylaniline
205-282-0
137-17-7
 Details
2,4,5-trimethylaniline hydrochloride
-
21436-97-5
 Details
2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane
219-863-1
2554-06-5
 Details
2,4,6-tri-tert-butylphenol
211-989-5
732-26-3
 Details
2,4-diaminoanisole sulphate
254-323-9
39156-41-7
 Details
2,4-diaminoanisole; 4-methoxy-m-phenylenediamine
210-406-1
615-05-4
 Details
2,4-dinitrotoluene
204-450-0
121-14-2
 Details
2,5-dinitrotoluene
210-581-4
619-15-8
 Details
2,6-dinitrotoluene
210-106-0
606-20-2
 Details
2,7-naphthalenedisulfonic acid, nickel(II) salt
-
72319-19-8
 Details
2-(2-aminoethylamino)ethanol; (AEEA)
203-867-5
111-41-1
 Details
2-(2-methoxyethoxy)ethanol; diethylene glycol monomethyl ether
203-906-6
111-77-3
 Details
2-(4-tert-butylbenzyl)propionaldehyde
201-289-8
80-54-6
 Details
2-[2-hydroxy-3-(2-chlorophenyl)carbamoyl-1-naphthylazo]-7-[2-hydroxy-3-(3-methylphenyl)carbamoyl-1-naphthylazo]fluoren-9-one
P-964
420-580-2
151798-26-4
 Details
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
CG 25-369; IRGACURE 369; TK 11-319
404-360-3
119313-12-1
 Details
2-bromopropane
200-855-1
75-26-3
 Details
2-butyryl-3-hydroxy-5-thiocyclohexan-3-yl-cyclohex-2-en-1-one
425-150-8
94723-86-1
 Details
2-chloro-6-fluoro-phenol
433-890-8
2040-90-6
 Details
2-ethoxyethanol; ethylene glycol monoethyl ether
203-804-1
110-80-5
 Details
2-ethoxyethyl acetate; ethylglycol acetate
203-839-2
111-15-9
 Details
2-ethylhexanoato-O)(neodecanoato-O)nickel
285-698-7
85135-77-9
 Details
2-ethylhexanoic acid and its salts, with the exception of those specified elsewhere in this Annex
-
-
 Details
2-ethylhexanoic acid, nickel salt
231-480-1
7580-31-6
 Details
2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate; [DOTE]
239-622-4
15571-58-1
 Details
2-ethylhexyl[[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]thio]acetate
279-452-8
80387-97-9
 Details
2-methoxyaniline; o-anisidine
201-963-1
90-04-0
 Details
2-methoxyethanol; ethylene glycol monomethyl ether
203-713-7
109-86-4
 Details
2-methoxyethyl acetate; methylglycol acetate
203-772-9
110-49-6
 Details
2-methoxypropanol
216-455-5
1589-47-5
 Details
2-methoxypropyl acetate
274-724-2
70657-70-4
 Details
2-methyl-1-(4-methylthiophenyl)-2-morpholinopropan-1-one
ACETOCURE 97; GENOCURE*PMP; IGM 4817; IRGACURE 907; SPEEDCURE 97
400-600-6
71868-10-5
 Details
2-methylaziridine; propyleneimine
200-878-7
75-55-8
 Details
2-methylimidazole
211-765-7
693-98-1
 Details
2-naphthylamine
202-080-4
91-59-8
 Details
2-Naphthylammonium chloride
210-313-6
612-52-2
 Details
2-nitroanisole
202-052-1
91-23-6
 Details
2-nitronaphthalene
209-474-5
581-89-5
 Details
2-nitropropane
201-209-1
79-46-9
 Details
2-nitrotoluene
201-853-3
88-72-2
 Details
3,3'-dichlorobenzidine; 3,3'-dichlorobiphenyl-4,4'-ylenediamine
202-109-0
91-94-1
 Details
3,3'-dimethoxybenzidine; o-dianisidine
204-355-4
119-90-4
 Details
3,4-dinitrotoluene
210-222-1
610-39-9
 Details
3,5-dinitrotoluene
210-566-2
618-85-9
 Details
3,7-dimethylocta-2,6-dienenitrile
225-918-0
5146-66-7
 Details
3-(3-biphenyl-4-yl-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxycoumarin; difenacoum
259-978-4
56073-07-5
 Details
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