carcinogens-mutagens-dir-2004-37

Carc and Muta Directive, Annex I - Substances, Mixtures & Processes

EU. Substances, Mixtures, Related Processes: Annex I & Art. 2, Dir 2004/37/EC (CMRD), as amended by Dir (EU) 2022/431, 16 March 2022

This list contains a non-exhaustive inventory of substances based on Art. 2 carcinogen, mutagen and reprotoxin (CMR) definitions and Annex I of the Carcinogens, Mutagens and Reprotoxins Directive (CMRD). Category 1A and 1B CMRs are derived from the CLP Regulation's Table 3 of Annex VI (1272/2008/EC). Employers are obligated to minimize worker exposure to these agents as far as possible, and must arrange for medical surveillance of workers exposed to these substances.

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Last updated 19 April 2024. Database contains 1292 unique substances/entries.
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Substance Name
EC No.
CAS No.
 
(1R,2S,5R)-2-[(4-chlorophenyl)methyl]-5-propan-2-yl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol
-
115850-69-6
 Details
(1R,2S,5S)-2-[(4-chlorophenyl)methyl]-5-propan-2-yl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol
-
115937-89-8
 Details
(2-chloroethyl)(3-hydroxypropyl)ammonium chloride
CLETOPROPAMINHYDROCHLORID
429-740-6
40722-80-3
 Details
(2-ethylhexanoato-O)(isodecanoato-O)nickel
284-351-7
84852-39-1
 Details
(2-ethylhexanoato-O)(isononanoato-O)nickel
287-470-2
85508-45-8
 Details
(3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)diammonium bis(hydrogen sulphate)
265-294-7
64969-36-4
 Details
(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane
SILANEOPHAN
405-020-7
105024-66-6
 Details
(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate
2691; CARTASOL BRILLANT SCHARLACH K-2GL KONZ.; CARTASOL BRILLANTSCHARLACH K-2GL FLÜSSIG (ZUBEREITUNG); CARTASOL BRILLANTSCHARLACH K-2GL GRANULAT (ZUBEREITUNG); CARTASOL BRILLIANT SCARLET K-2GL; CARTASOL BRILLIANT SCARLET K-2GL CONC.
402-060-7
108225-03-2
 Details
(E)-3-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
CP-166,221
428-010-4
82413-20-5
 Details
(isodecanoato-O)(isononanoato-O)nickel
284-348-0
84852-36-8
 Details
(isodecanoato-O)(isooctanoato-O)nickel
285-909-2
85166-19-4
 Details
(isononanoato-O)(isooctanoato-O)nickel
287-471-8
85508-46-9
 Details
(isononanoato-O)(neodecanoato-O)nickel
287-592-6
85551-28-6
 Details
(isooctanoato-O)(neodecanoato-O)nickel
284-347-5
84852-35-7
 Details
(methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'dipyridinium dichloride dihydrochloride
CARTASOL GEEL M-GL CONC.; CARTASOL GELB M-GL FLÜSSIG (ZUBEREITUNG); CARTASOL GELB M-GL KONZ.; CARTASOL YELLOW M-GL CONC.; HM 2580
401-500-5
118658-99-4
 Details
(R)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
226-908-9
5543-58-8
 Details
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
226-907-3
5543-57-7
 Details
1,2,3-trichloropropane
202-486-1
96-18-4
 Details
1,2,4-triazole
206-022-9
288-88-0
 Details
1,2-benzenedicarboxylic acid, dihexyl ester, branched and linear
271-093-5
68515-50-4
 Details
1,2-benzenedicarboxylic acid, dipentylester, branched and linear
284-032-2
84777-06-0
 Details
1,2-benzenedicarboxylic acid; di-C6-8-branched alkylesters, C7-rich
276-158-1
71888-89-6
 Details
1,2-benzenedicarboxylic acid; di-C7-11-branched and linear alkylesters
271-084-6
68515-42-4
 Details
1,2-bis(2-methoxyethoxy)ethane; TEGDME; triethylene glycol dimethyl ether; triglyme
203-977-3
112-49-2
 Details
1,2-dibromo-3-chloropropane
202-479-3
96-12-8
 Details
1,2-dibromoethane
203-444-5
106-93-4
 Details
1,2-dichloroethane; ethylene dichloride
203-458-1
107-06-2
 Details
1,2-dichloropropane; propylene dichloride
201-152-2
78-87-5
 Details
1,2-diethoxyethane
211-076-1
629-14-1
 Details
1,2-dihydroxybenzene; pyrocatechol
204-427-5
120-80-9
 Details
1,2-dimethoxyethane; ethylene glycol dimethyl ether; EGDME
203-794-9
110-71-4
 Details
1,2-dimethylhydrazine
-
540-73-8
 Details
1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione; TGIC
219-514-3
2451-62-9
 Details
1,3,5-tris-[(2S and 2R)-2,3-epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione
TEPIC-H
423-400-0
59653-74-6
 Details
1,3-butadiene; buta-1,3-diene
203-450-8
106-99-0
 Details
1,3-dichloro-2-propanol
202-491-9
96-23-1
 Details
1,3-propanesultone; 1,2-oxathiolane 2,2-dioxide
214-317-9
1120-71-4
 Details
1,4,5,8-tetraaminoanthra; quinone; C.I. Disperse Blue 1
219-603-7
2475-45-8
 Details
1,4-Benzenediamine, N,N’-mixed Ph and tolyl derivs.
273-227-8
68953-84-4
 Details
1,4-dichlorobut-2-ene
212-121-8
764-41-0
 Details
1,4-dioxane
204-661-8
123-91-1
 Details
1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride [containing ≥ 0,1 % 4-chloroaniline (EC No 203-401-0)]
433-580-2
214353-17-0
 Details
1-bromopropane; n-propyl bromide
203-445-0
106-94-5
 Details
1-chloro-2,3-epoxypropane; epichlorhydrin
203-439-8
106-89-8
 Details
1-methyl-3-nitro-1-nitrosoguanidine
200-730-1
70-25-7
 Details
1-vinylimidazole
214-012-0
1072-63-5
 Details
2,2',6,6'-tetrabromo–4,4'-isopropylidenediphenol; tetrabromobisphenol-A
201-236-9
79-94-7
 Details
2,2'-(nitrosoimino)bisethanol
214-237-4
1116-54-7
 Details
2,2'-bioxirane; 1,2:3,4-diepoxybutane
215-979-1
1464-53-5
 Details
2,2'-dichloro-4,4'-methylenedianiline; 4,4'-methylene bis(2-chloroaniline)
202-918-9
101-14-4
 Details
2,2-bis(bromomethyl)propane-1,3-diol
221-967-7
3296-90-0
 Details
2,2-dimethylpropan-1-ol, tribromo derivative
253-057-0
36483-57-5
 Details
2,3-dibromopropan-1-ol; 2,3-dibromo-1-propanol
202-480-9
96-13-9
 Details
2,3-dinitrotoluene
210-013-5
602-01-7
 Details
2,3-epoxypropan-1-ol; glycidol; oxiranemethanol
209-128-3
556-52-5
 Details
2,3-epoxypropyl methacrylate; glycidyl methacrylate
203-441-9
106-91-2
 Details
2,3-epoxypropyltrimethylammonium chloride ... %; glycidyl trimethylammonium chloride ... %
221-221-0
3033-77-0
 Details
2,4,5-trimethylaniline
205-282-0
137-17-7
 Details
2,4,5-trimethylaniline hydrochloride
-
21436-97-5
 Details
2,4,6-tri-tert-butylphenol
211-989-5
732-26-3
 Details
2,4-diaminoanisole sulphate
254-323-9
39156-41-7
 Details
2,4-diaminoanisole; 4-methoxy-m-phenylenediamine
210-406-1
615-05-4
 Details
2,4-dinitrotoluene
204-450-0
121-14-2
 Details
2,5-dinitrotoluene
210-581-4
619-15-8
 Details
2,6-dinitrotoluene
210-106-0
606-20-2
 Details
2,7-naphthalenedisulfonic acid, nickel(II) salt
-
72319-19-8
 Details
2-(2-aminoethylamino)ethanol; (AEEA)
203-867-5
111-41-1
 Details
2-(2-methoxyethoxy)ethanol; diethylene glycol monomethyl ether
203-906-6
111-77-3
 Details
2-(4-tert-butylbenzyl)propionaldehyde
201-289-8
80-54-6
 Details
2-[2-hydroxy-3-(2-chlorophenyl)carbamoyl-1-naphthylazo]-7-[2-hydroxy-3-(3-methylphenyl)carbamoyl-1-naphthylazo]fluoren-9-one
P-964
420-580-2
151798-26-4
 Details
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
CG 25-369; IRGACURE 369; TK 11-319
404-360-3
119313-12-1
 Details
2-bromopropane
200-855-1
75-26-3
 Details
2-butyryl-3-hydroxy-5-thiocyclohexan-3-yl-cyclohex-2-en-1-one
425-150-8
94723-86-1
 Details
2-chloro-6-fluoro-phenol
433-890-8
2040-90-6
 Details
2-ethoxyethanol; ethylene glycol monoethyl ether
203-804-1
110-80-5
 Details
2-ethoxyethyl acetate; ethylglycol acetate
203-839-2
111-15-9
 Details
2-ethylhexanoato-O)(neodecanoato-O)nickel
285-698-7
85135-77-9
 Details
2-ethylhexanoic acid and its salts, with the exception of those specified elsewhere in this Annex
show/hide
2-ethylhexanoic acid EC / List no: 205-743-6 | CAS no: 149-57-5
Metal salts of 2-ethylhexanoic acid EC / List no: - | CAS no: -
-
-
 Details
2-ethylhexanoic acid, nickel salt
231-480-1
7580-31-6
 Details
2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate; [DOTE]
239-622-4
15571-58-1
 Details
2-ethylhexyl[[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]thio]acetate
279-452-8
80387-97-9
 Details
2-methoxyaniline; o-anisidine
201-963-1
90-04-0
 Details
2-methoxyethanol; ethylene glycol monomethyl ether
203-713-7
109-86-4
 Details
2-methoxyethyl acetate; methylglycol acetate
203-772-9
110-49-6
 Details
2-methoxyethyl acrylate
221-499-3
3121-61-7
 Details
2-methoxypropanol
216-455-5
1589-47-5
 Details
2-methoxypropyl acetate
274-724-2
70657-70-4
 Details
2-methyl-1-(4-methylthiophenyl)-2-morpholinopropan-1-one
ACETOCURE 97; GENOCURE*PMP; IGM 4817; IRGACURE 907; SPEEDCURE 97
400-600-6
71868-10-5
 Details
2-methylaziridine; propyleneimine
200-878-7
75-55-8
 Details
2-methylimidazole
211-765-7
693-98-1
 Details
2-naphthylamine
202-080-4
91-59-8
 Details
2-Naphthylammonium chloride
210-313-6
612-52-2
 Details
2-nitroanisole
202-052-1
91-23-6
 Details
2-nitronaphthalene
209-474-5
581-89-5
 Details
2-nitropropane
201-209-1
79-46-9
 Details
2-nitrotoluene
201-853-3
88-72-2
 Details
3,3'-dichlorobenzidine; 3,3'-dichlorobiphenyl-4,4'-ylenediamine
202-109-0
91-94-1
 Details
3,3'-dimethoxybenzidine; o-dianisidine
204-355-4
119-90-4
 Details
3,4-dinitrotoluene
210-222-1
610-39-9
 Details
3,5-dinitrotoluene
210-566-2
618-85-9
 Details
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