carcinogens-mutagens-dir-2004-37

Carc and Muta Directive, Annex I - Substances, Mixtures & Processes

EU. Substances, Mixtures, Related Processes: Annex I & Art. 2, Dir 2004/37/EC (CMRD), as amended by Dir (EU) 2022/431, 16 March 2022

This list contains a non-exhaustive inventory of substances based on Art. 2 carcinogen, mutagen and reprotoxin (CMR) definitions and Annex I of the Carcinogens, Mutagens and Reprotoxins Directive (CMRD). Category 1A and 1B CMRs are derived from the CLP Regulation's Table 3 of Annex VI (1272/2008/EC). Employers are obligated to minimize worker exposure to these agents as far as possible, and must arrange for medical surveillance of workers exposed to these substances.

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Last updated 08 December 2023. Database contains 1277 unique substances/entries.
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Substance Name
EC No.
CAS No.
 
2-ethylhexanoic acid, nickel salt
231-480-1
7580-31-6
 Details
2-ethylhexanoic acid and its salts, with the exception of those specified elsewhere in this Annex
-
-
 Details
2-ethylhexanoato-O)(neodecanoato-O)nickel
285-698-7
85135-77-9
 Details
2-ethoxyethyl acetate; ethylglycol acetate
203-839-2
111-15-9
 Details
2-ethoxyethanol; ethylene glycol monoethyl ether
203-804-1
110-80-5
 Details
2-chloro-6-fluoro-phenol
433-890-8
2040-90-6
 Details
2-butyryl-3-hydroxy-5-thiocyclohexan-3-yl-cyclohex-2-en-1-one
425-150-8
94723-86-1
 Details
2-bromopropane
200-855-1
75-26-3
 Details
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
CG 25-369; IRGACURE 369; TK 11-319
404-360-3
119313-12-1
 Details
2-[2-hydroxy-3-(2-chlorophenyl)carbamoyl-1-naphthylazo]-7-[2-hydroxy-3-(3-methylphenyl)carbamoyl-1-naphthylazo]fluoren-9-one
P-964
420-580-2
151798-26-4
 Details
2-(4-tert-butylbenzyl)propionaldehyde
201-289-8
80-54-6
 Details
2-(2-methoxyethoxy)ethanol; diethylene glycol monomethyl ether
203-906-6
111-77-3
 Details
2-(2-aminoethylamino)ethanol; (AEEA)
203-867-5
111-41-1
 Details
2,7-naphthalenedisulfonic acid, nickel(II) salt
-
72319-19-8
 Details
2,6-dinitrotoluene
210-106-0
606-20-2
 Details
2,5-dinitrotoluene
210-581-4
619-15-8
 Details
2,4-dinitrotoluene
204-450-0
121-14-2
 Details
2,4-diaminoanisole; 4-methoxy-m-phenylenediamine
210-406-1
615-05-4
 Details
2,4-diaminoanisole sulphate
254-323-9
39156-41-7
 Details
2,4,6-tri-tert-butylphenol
211-989-5
732-26-3
 Details
2,4,5-trimethylaniline hydrochloride
-
21436-97-5
 Details
2,4,5-trimethylaniline
205-282-0
137-17-7
 Details
2,3-epoxypropyltrimethylammonium chloride ... %; glycidyl trimethylammonium chloride ... %
221-221-0
3033-77-0
 Details
2,3-epoxypropyl methacrylate; glycidyl methacrylate
203-441-9
106-91-2
 Details
2,3-epoxypropan-1-ol; glycidol; oxiranemethanol
209-128-3
556-52-5
 Details
2,3-dinitrotoluene
210-013-5
602-01-7
 Details
2,3-dibromopropan-1-ol; 2,3-dibromo-1-propanol
202-480-9
96-13-9
 Details
2,2-dimethylpropan-1-ol, tribromo derivative
253-057-0
36483-57-5
 Details
2,2-bis(bromomethyl)propane-1,3-diol
221-967-7
3296-90-0
 Details
2,2'-dichloro-4,4'-methylenedianiline; 4,4'-methylene bis(2-chloroaniline)
202-918-9
101-14-4
 Details
2,2'-bioxirane; 1,2:3,4-diepoxybutane
215-979-1
1464-53-5
 Details
2,2'-(nitrosoimino)bisethanol
214-237-4
1116-54-7
 Details
1-vinylimidazole
214-012-0
1072-63-5
 Details
1-methyl-3-nitro-1-nitrosoguanidine
200-730-1
70-25-7
 Details
1-chloro-2,3-epoxypropane; epichlorhydrin
203-439-8
106-89-8
 Details
1-bromopropane; n-propyl bromide
203-445-0
106-94-5
 Details
1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride [containing ≥ 0,1 % 4-chloroaniline (EC No 203-401-0)]
433-580-2
214353-17-0
 Details
1,4-dioxane
204-661-8
123-91-1
 Details
1,4-dichlorobut-2-ene
212-121-8
764-41-0
 Details
1,4,5,8-tetraaminoanthra; quinone; C.I. Disperse Blue 1
219-603-7
2475-45-8
 Details
1,3-propanesultone; 1,2-oxathiolane 2,2-dioxide
214-317-9
1120-71-4
 Details
1,3-dichloro-2-propanol
202-491-9
96-23-1
 Details
1,3-butadiene; buta-1,3-diene
203-450-8
106-99-0
 Details
1,3,5-tris-[(2S and 2R)-2,3-epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione
TEPIC-H
423-400-0
59653-74-6
 Details
1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione; TGIC
219-514-3
2451-62-9
 Details
1,2-dimethylhydrazine
-
540-73-8
 Details
1,2-dimethoxyethane; ethylene glycol dimethyl ether; EGDME
203-794-9
110-71-4
 Details
1,2-dihydroxybenzene; pyrocatechol
204-427-5
120-80-9
 Details
1,2-diethoxyethane
211-076-1
629-14-1
 Details
1,2-dichloropropane; propylene dichloride
201-152-2
78-87-5
 Details
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