carcinogens-mutagens-dir-2004-37

Carc and Muta Directive, Annex I - Substances, Mixtures & Processes

EU. Substances, Mixtures, Related Processes: Annex I & Art. 2, Dir 2004/37/EC (CMRD), as amended by Dir (EU) 2022/431, 16 March 2022

This list contains a non-exhaustive inventory of substances based on Art. 2 carcinogen, mutagen and reprotoxin (CMR) definitions and Annex I of the Carcinogens, Mutagens and Reprotoxins Directive (CMRD). Category 1A and 1B CMRs are derived from the CLP Regulation's Table 3 of Annex VI (1272/2008/EC). Employers are obligated to minimize worker exposure to these agents as far as possible, and must arrange for medical surveillance of workers exposed to these substances.

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Last updated 24 April 2024. Database contains 1292 unique substances/entries.
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Substance Name
EC No.
CAS No.
 
1,2-dibromoethane
203-444-5
106-93-4
 Details
1,2-dichloroethane; ethylene dichloride
203-458-1
107-06-2
 Details
1,2-dichloropropane; propylene dichloride
201-152-2
78-87-5
 Details
1,2-diethoxyethane
211-076-1
629-14-1
 Details
1,2-dihydroxybenzene; pyrocatechol
204-427-5
120-80-9
 Details
1,2-dimethoxyethane; ethylene glycol dimethyl ether; EGDME
203-794-9
110-71-4
 Details
1,2-dimethylhydrazine
-
540-73-8
 Details
1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione; TGIC
219-514-3
2451-62-9
 Details
1,3,5-tris-[(2S and 2R)-2,3-epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione
TEPIC-H
423-400-0
59653-74-6
 Details
1,3-butadiene; buta-1,3-diene
203-450-8
106-99-0
 Details
1,3-dichloro-2-propanol
202-491-9
96-23-1
 Details
1,3-propanesultone; 1,2-oxathiolane 2,2-dioxide
214-317-9
1120-71-4
 Details
1,4,5,8-tetraaminoanthra; quinone; C.I. Disperse Blue 1
219-603-7
2475-45-8
 Details
1,4-Benzenediamine, N,N’-mixed Ph and tolyl derivs.
273-227-8
68953-84-4
 Details
1,4-dichlorobut-2-ene
212-121-8
764-41-0
 Details
1,4-dioxane
204-661-8
123-91-1
 Details
1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride [containing ≥ 0,1 % 4-chloroaniline (EC No 203-401-0)]
433-580-2
214353-17-0
 Details
1-bromopropane; n-propyl bromide
203-445-0
106-94-5
 Details
1-chloro-2,3-epoxypropane; epichlorhydrin
203-439-8
106-89-8
 Details
1-methyl-3-nitro-1-nitrosoguanidine
200-730-1
70-25-7
 Details
1-vinylimidazole
214-012-0
1072-63-5
 Details
2,2',6,6'-tetrabromo–4,4'-isopropylidenediphenol; tetrabromobisphenol-A
201-236-9
79-94-7
 Details
2,2'-(nitrosoimino)bisethanol
214-237-4
1116-54-7
 Details
2,2'-bioxirane; 1,2:3,4-diepoxybutane
215-979-1
1464-53-5
 Details
2,2'-dichloro-4,4'-methylenedianiline; 4,4'-methylene bis(2-chloroaniline)
202-918-9
101-14-4
 Details
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