Brief Profile

Data platform availability banner - brief profile

Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
231-113-5
CAS no.:
7440-03-1
Index number:
Molecular formula:
Nb
SMILES:
[Nb]
InChI:
InChI=1S/Nb
Type of substance:
Mono constituent substance
Origin:
Element
Registered compositions:
30
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the classification provided by companies to ECHA in REACH registrations this substance is a flammable solid.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance catches fire spontaneously if exposed to air.

Breakdown of all 491 C&L notifications submitted to ECHA

Not Classified
Flam. Sol. 1 H228
Pyr. Sol. 1 H250
Eye Irrit. 2 H319
Skin Irrit. 2 H315
Flam. Sol. 2 H228
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa-term.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa-term.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa-term.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 56 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: metals, welding & soldering products and metal surface treatment products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), hot work operations with metals (e.g. welding, soldering, gouging, brazing, flame cutting), potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), open transfer and processing with minerals/metals at elevated temperature and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting). Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and vehicles. This substance can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery).

This substance is used in the following products: metals, welding & soldering products, laboratory chemicals and semiconductors.

This substance is used in the following areas: building & construction work. This substance is used for the manufacture of: fabricated metal products, machinery and vehicles, metals and electrical, electronic and optical equipment.

This substance is used in the following activities or processes at workplace: hot work operations with metals (e.g. welding, soldering, gouging, brazing, flame cutting), open transfer and processing with minerals/metals at elevated temperature, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), the low energy manipulation of substances bound in materials or articles, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding) and mixing in open batch processes.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: metals, welding & soldering products and laboratory chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers and open transfer and processing with minerals/metals at elevated temperature.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: metals, welding & soldering products, metal surface treatment products and laboratory chemicals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: scientific research and development and formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: metals, fabricated metal products, machinery and vehicles and electrical, electronic and optical equipment.

This substance is used in the following activities or processes at workplace: transfer of chemicals, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), hot work operations with metals (e.g. welding, soldering, gouging, brazing, flame cutting) and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: in the production of articles, of substances in closed systems with minimal release and in processing aids at industrial sites.

This substance is used in the following activities or processes at workplace: potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), transfer of chemicals, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes and hot work operations with metals (e.g. welding, soldering, gouging, brazing, flame cutting).

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; ground and bond container and receiving equipment; use explosion-proof equipment (electrical/ventilating/lighting/etc.); wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: In case of fire: follow instructions specified by manufacturer/supplier.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • AFFILIPS NV, Biezenstraat 26-31 3300 Tienen Belgium
  • AFT-HUNGARY Kft, Ipari Park 5 2651 Rétság Hungary
  • Arcam AB, Designvägen 2 43533 Mölnlycke Sweden
  • B-Lands Consulting (8111119-1), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • B-Lands Consulting (811569-4), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811570-8), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811738-2), BP 1516 5 Place Robert Schuman 38025 Grenoble France France
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Belmet Handelsgesellschaft m.b.H., Gruberstraße 2-4 4020 Linz Austria
  • Bruker EAS GmbH, Ehrichstrasse 10 63450 Hanau Germany
  • Buss & Buss Spezialmetalle GmbH, Sassnitzer Strasse 10 18551 Sagard Germany
  • CBMM Europe BV, Zuidplein 96 1077 XV Amsterdam Netherlands
  • Chementors Oy, Raisionkaari 55 21200 Raisio Finland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland
  • Chemservice GmbH - (P0UT), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • CRONIMET Raw Materials GmbH, Südbeckenstraße 22 76189 Karlsruhe Germany
  • Electro Optical Systems Finland Oy, Lemminkäisenkatu 36 20520 Turku Finland
  • EVOCHEM Advanced Materials GmbH, Heinrich-Krumm-Strasse 20 63073 Offenbach am Main Germany
  • ExponentOR18I, Block 1, Blanchardstown Corporate Park Ballycoolin Road, Blanchardstown D15 AKK1 Dublin Ireland
  • Forgital Italy S.p.A., Via Spezzapria 1 36010 Seghe di Velo d'Astico VI Italy
  • FRAMATOME, 291, Route de l’Electro-Chimie 38560 JARRIE France
  • GE Avio S.r.l., via I Maggio 99 10040 Rivalta di Torino (TO) Italy
  • GfE Metalle & Materialien GmbH, Höfener Str. 45 90431 Nürnberg Germany
  • GfE Metalle und Materialien GmbH, Hoefener Str. 45 90431 Nuernberg Bavaria Germany
  • GfE-MIR GmbH, Berliner Allee 51-53 D-40212 Düsseldorf Nordrhein-Westfalen Germany
  • Grondmet GmbH & Co. KG, Luegallee 79 40545 Düsseldorf Germany
  • Grondmet Verwaltungs GmbH, Luegallee 79 40545 Düsseldorf Germany
  • H.C.Starck Hermsdorf GmbH, Robert-Friese-Strasse 4 D-07629 Hermsdorf Germany
  • HOWMET SAS, 68/78 rue du moulin de cage 92230 Gennevilliers France
  • INTERTEK FRANCE, ZI ECOPARC II 27400 HEUDEBOUVILLE France
  • Lipmann Walton Ireland Limited, c/o Crowleys DFK Unlimited Company 16/17 College Green D02 V078 Dublin Ireland
  • Magnequench GmbH, Österbergstraße 9 D - 72074 Tübingen Germany
  • MBR Metals, Vabaõhumuuseumi tee 1 13522 Tallinn Estonia
  • Metherma KG, Arnheimer Strasse 109 40489 Düsseldorf Germany
  • MINERALS & METALS ITALIA SPA, via Leopardi n. 26 24060 ROGNO BERGAMO Italy
  • Niobec GmbH, Kaiserswerther Straße 135 40474 Düsseldorf Germany
  • Nordmet, Tartu mnt. 10 10145 Tallinn Estonia
  • NPM Silmet OÜ, Kesk tn. 2 40231 Sillamäe Ida- Virumaa Estonia
  • PLANSEE SE, Metallwerk-Plansee-Str. 71 A-6600 Reutte Tyrol Austria
  • Praxair Surface Technologies GmbH, Am Muehlbach 13 87487 Wiggensbach Germany
  • REACH Advice GmbH OR9, Dechant-Wolfgarten-Str. 7 53925 Kall Germany
  • Sinter srl, Via Dossi 19 25050 Pian Camuno - Brescia Italy
  • SPS International Ltd (OR to Cannon-Muskegon Corporation), Bays 122-125 Shannon Industrial Estate V14 TP27 Shannon Co. Clare Ireland
  • SPS International Ltd (OR to Huntington Alloys Corporation), Bays 122-125 Shannon Industrial Estate V14 TP27 Shannon Co. Clare Ireland
  • SPS International Ltd (OR to Special Metals New Hartford), Bays 122-125 Shannon Industrial Estate V14 TP27 Shannon Co. Clare Ireland
  • SPS International Ltd (OR to Timet Inc), Bays 122-125 Shannon Industrial Estate V14 TP27 Shannon Co. Clare Ireland
  • SPS International Ltd (OR to Western Australian Specialty Alloys Pty. Ltd), Bays 122-125 Shannon Industrial Estate V14 TP27 Shannon Co. Clare Ireland
  • TANIOBIS GmbH, lm Schleeke 78-91 38642 Goslar Germany
  • TANIOBIS Smelting GmbH & Co. KG, Im Schleeke 78 -91 38642 Goslar Germany
  • TiFast srl, Zona Industriale San Liberato 05035 Narni Italy
  • Traxys Europe SA, 19-21 Route Arlon same L-8009 Strassen Luxembourg Luxembourg
  • Umicore Thin Film Products AG, Alte Landstrasse 8 FL-9496 Balzers Liechtenstein
  • VDM Metals International GmbH, Plettenberger Str. 2 58791 Werdohl Germany
  • Yordas GmbH, Äußere Nürnberger Str. 6 91301 Forchheim Germany
  • Zensho Europe GmbH, Steinstr. 27 40210 Duesseldorf N/A Germany
  • [Confidential], [Confidential]
  • Avon Specialty Metals Ltd, Empire Way GL2 5HY Gloucester United Kingdom
  • COMETAL, S.A., José Lázaro Galdiano 4, 4ª Planta 28036 Madrid Spain
  • DHI, Agern Allé 5 DK-2970 Hoersholm Denmark
  • Sovereign International Alloys & Metals Ltd., 3-4 Bower Terrace ME16 8RY Maidstone, KENT United Kingdom

Substance names and other identifiers

Niobium
EC Inventory, REACH pre-registration
Niobium
REACH pre-registration, Other
Columbium
C&L Inventory
Columbium/Niobium
C&L Inventory
Elemental niob use of alloys in powder form.
Registration dossier
Nb
C&L Inventory
niob
C&L Inventory
Niobium
C&L Inventory, Registration dossier, Other
Niobium
C&L Inventory, Registration dossier, Other
niobium (2+)
Registration dossier
Niobium (Nb)
Registration dossier
Niobium in alloys
Registration dossier
Niobium Metal
Registration dossier
niobium(2+)
C&L Inventory, Registration dossier
niubium
C&L Inventory
noibium
C&L Inventory
Columbium
Registration dossier
Ferro Niobium Tantalum Alloy
Registration dossier
Niob
Registration dossier
Niobium
Registration dossier
Niobium metal
Registration dossier
NiobNiobiumFeNbFerroniobFerroniobium
Registration dossier
26842-13-7
CAS number
Other
7440-03-1
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 4 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [2]
C Form
Compact (50%), Powder (50%) [2]
C Odour
Odourless (100%) [1]
C Substance type
Inorganic (100%) [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 2 studies processed
R Melting / freezing point
2 477 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Melting / freezing point at 101 325 Pa
2 477 °C

Boiling point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 3 studies submitted
  • 2 studies processed
R Density
8.57 g/cm³ @ 20 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Relative density at 20°C
8.57

Vapour pressure

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 8 studies submitted
  • 5 studies processed
R Water solubility (mass/vol.)
10 - 15 000 ng/L @ 20 - 21.5 °C and pH 5.5 - 8 [12]

Type of Study provided
Studies with data
Key study 7
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Water solubility
1 µg/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 5
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 11 studies submitted
  • 5 studies processed
C Interpretation of results
Non flammable (60%), Not classified based on GHS criteria (20%), Highly flammable (20%) [5]

Type of Study provided
Studies with data
Key study 5
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 6
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
C Summaries
  • 2 summaries submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 3
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (2)
Intermittent releases (freshwater) No hazard identified (2)
Marine water No hazard identified (2)
Intermittent releases (marine water) No hazard identified (2)
Sewage treatment plant (STP) No hazard identified (2)
Sediment (freshwater) No hazard identified (2)
Sediment (marine water) No hazard identified (2)
Hazard for Air
Air No hazard identified (2)
Hazard for Terrestrial Organism
Soil No hazard identified (2)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (2)

Short–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
NOEC (21 days) 10 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 100 mg/L [1]
NOEC (72 h) 10 mg/L [1]
EC10 (72 h) 16.1 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (3 h) 1 g/L [1]
NOEC (3 h) 1 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 23.5 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 3.3 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 5.8 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.67 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.67 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2 1 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 3 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Other [1]

Type of Study provided
oral
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
inhalation
  • 4 studies submitted
  • 1 study processed
P/RResults
LC50 (4 h) 5.45 mg/L air (rat) [1]
M/CInterpretations of results
Other [1]

inhalation
Studies with data
Key study 1 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
dermal
  • 2 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [2]
M/CInterpretations of results
Not classified [1]

dermal
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 2 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 5 mg/L air
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 5 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 1 000 mg/kg bw (total dose) [1]

Type of Study provided
Study data: oral
Studies with data
Key study 1 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Study data: inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oral route - systemic effects:
No adverse effect observed NOAEL 1 000 mg/kg bw/day (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Study results
Study data: reproduction
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 1 000 mg/kg bw/day (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant