Domain Chemical legislation

Definition A substance, man-made or natural, which can interfere with the hormone systems of humans and wildlife, with potentially adverse effects, for example, on fertility and neural development.
Definition Ref. Institute for Health and Consumer Protection (IHCP), Joint Research Centre, URL:


endocrine disrupter
Term Ref. ECHA General Report 2011, URL:
Context The priority areas in 2011 were genotoxicity, in vitro tests (e.g. for skin and eye irritation/corrosion and sensitisation), reproductive toxicity, especially the Extended One-Generation Reproductive Toxicity study, endocrine disrupters, ecotoxicity (aquatic, sediment, soil), and bioaccumulation.
Context Ref. ECHA General Report 2011, URL: